Sweet complementarity: the functional pairing of glycans with lectins

Network Monitoring of Adhesion/Growth-Regulatory Galectins: Localization of the Five Canonical Chicken Proteins in Embryonic and Maturing Bone and Cartilage and Their Introduction as Histochemical Tools

(2015) Herbert Kaltner et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Dissecting Molecular Aspects of Cell Interactions Using Glycodendrimersomes with Programmable Glycan Presentation and Engineered Human Lectins

(2015) Shaodong Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

X-ray reflectivity and grazing incidence diffraction studies of interaction between human adhesion/growth-regulatory galectin-1 and DPPE—GM1 lipid monolayer at an air/water interface

(2015) J. Majewski et al.   BIOCHEMISTRY-MOSCOW

A guide into glycosciences: How chemistry, biochemistry and biology cooperate to crack the sugar code

(2015) Dolores Solís et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Engineering a Therapeutic Lectin by Uncoupling Mitogenicity from Antiviral Activity

(2015) Michael D. Swanson et al.   CELL

Combining Crystallography and Hydrogen-Deuterium Exchange to Study Galectin-Ligand Complexes

(2015) Federico M. Ruiz et al.   CHEMISTRY-A EUROPEAN JOURNAL

Comparative lectinology: Delineating glycan-specificity profiles of the chicken galectins using neoglycoconjugates in a cell assay

(2015) E. M. Rapoport et al.   GLYCOBIOLOGY

Antibody recognition of carbohydrate epitopes

(2015) Omid Haji-Ghassemi et al.   GLYCOBIOLOGY

Merging carbohydrate chemistry with lectin histochemistry to study inhibition of lectin binding by glycoclusters in the natural tissue context

(2015) Sabine André et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Functional interplay between ganglioside GM1 and cross-linking galectin-1 induces axon-like neuritogenesis via integrin-based signaling and TRPC5-dependent Ca2+influx

(2015) Gusheng Wu et al.   JOURNAL OF NEUROCHEMISTRY

Glycodendrimersomes from Sequence-Defined Janus Glycodendrimers Reveal High Activity and Sensor Capacity for the Agglutination by Natural Variants of Human Lectins

(2015) Shaodong Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

3-O-sulfo-β-d-galactose moiety of endogenous sulfoglycolipids is a potential ligand for immunoglobulin-like receptor LMIR5

(2015) Vongsavanh Phongsisay et al.   MOLECULAR IMMUNOLOGY

Lectins: Getting Familiar with Translators of the Sugar Code

(2015) Sabine André et al.   MOLECULES

Recognition of microbial glycans by human intelectin-1

(2015) Darryl A Wesener et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Unraveling functional significance of natural variations of a human galectin by glycodendrimersomes with programmable glycan surface

(2015) Shaodong Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural significance of galectin design: impairment of homodimer stability by linker insertion and partial reversion by ligand presence

(2015) Sabine Vértesy et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Sugar coating: bacterial protein glycosylation and host–microbe interactions

(2015) Felicia Y.Y. Tan et al.   TRENDS IN BIOCHEMICAL SCIENCES

The magic of the sugar code

(2015) Hans-Joachim Gabius   TRENDS IN BIOCHEMICAL SCIENCES

The glycobiology of the CD system: a dictionary for translating marker designations into glycan/lectin structure and function

(2015) Hans-Joachim Gabius et al.   TRENDS IN BIOCHEMICAL SCIENCES

Axon glycoprotein routing in nerve polarity, function, and repair

(2015) José Abad-Rodríguez et al.   TRENDS IN BIOCHEMICAL SCIENCES

Glycan variation and evolution in the eukaryotes

(2015) Anthony P. Corfield et al.   TRENDS IN BIOCHEMICAL SCIENCES

Gangliosides: glycosphingolipids essential for normal neural development and function

(2015) Cara-Lynne Schengrund   TRENDS IN BIOCHEMICAL SCIENCES

Congenital disorders of glycosylation: a concise chart of glycocalyx dysfunction

(2015) Thierry Hennet et al.   TRENDS IN BIOCHEMICAL SCIENCES

Recognition of microbial glycans by human intelectin-1

(2015) Darryl A Wesener et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Galectin-3 leads to attenuation of apoptosis through Bax heterodimerization in human thyroid carcinoma cells

(2015) Yosuke Harazono et al.   Oncotarget

Dual Roles of Gastric Gland Mucin-specific O-glycans in Prevention of Gastric Cancer

(2014) Jun Nakayama   ACTA HISTOCHEMICA ET CYTOCHEMICA

Human chimera-type galectin-3: Defining the critical tail length for high-affinity glycoprotein/cell surface binding and functional competition with galectin-1 in neuroblastoma cell growth regulation

(2014) Jürgen Kopitz et al.   BIOCHIMIE

Natural single amino acid polymorphism (F19Y) in human galectin-8: detection of structural alterations and increased growth-regulatory activity on tumor cells

(2014) Federico M. Ruiz et al.   FEBS Journal

Defining the conformation of human mincle that interacts with mycobacterial trehalose dimycolate

(2014) Sabine A F Jégouzo et al.   GLYCOBIOLOGY

Human osteoarthritic knee cartilage: fingerprinting of adhesion/growth-regulatory galectins in vitro and in situ indicates differential upregulation in severe degeneration

(2014) Stefan Toegel et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Neu3 Sialidase-Mediated Ganglioside Conversion Is Necessary for Axon Regeneration and Is Blocked in CNS Axons

(2014) S. Kappagantula et al.   JOURNAL OF NEUROSCIENCE

N-Linked Glycosylation in Archaea: a Structural, Functional, and Genetic Analysis

(2014) Ken F. Jarrell et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The Sweet Tooth of Bacteria: Common Themes in Bacterial Glycoconjugates

(2014) H. L. P. Tytgat et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling

(2014) Renata Grozovsky et al.   NATURE MEDICINE

Structural Basis for Selective Recognition of Endogenous and Microbial Polysaccharides by Macrophage Receptor SIGN-R1

(2014) Noella Silva-Martín et al.   STRUCTURE

Desialylation of surface receptors as a new dimension in cell signaling

(2013) A. V. Pshezhetsky et al.   BIOCHEMISTRY-MOSCOW

Context-dependent multifunctionality of galectin-1: a challenge for defining the lectin as therapeutic target

(2013) Karel Smetana et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Copy-number variation of functional galectin genes: Studying animal galectin-7 (p53-induced gene 1 in man) and tandem-repeat-type galectins-4 and -9

(2013) Herbert Kaltner et al.   GLYCOBIOLOGY

Complex N-glycans: the story of the “yellow brick road”

(2013) Harry Schachter   GLYCOCONJUGATE JOURNAL

DC-SIGN, DC-SIGNR and LSECtin: C-Type Lectins for Infection

(2013) Feng Zhang et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Common Polymorphisms in Human Langerin Change Specificity for Glycan Ligands

(2013) Hadar Feinberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuronal Galectin-4 is required for axon growth and for the organization of axonal membrane L1 delivery and clustering

(2013) Silvia Velasco et al.   JOURNAL OF NEUROCHEMISTRY

Modular Synthesis of Amphiphilic Janus Glycodendrimers and Their Self-Assembly into Glycodendrimersomes and Other Complex Architectures with Bioactivity to Biomedically Relevant Lectins

(2013) Virgil Percec et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL

(2013) A. Furukawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beyond glycoproteins as galectin counterreceptors: tumor-effector T cell growth control via ganglioside GM1

(2012) Robert W. Ledeen et al.   Annals of the New York Academy of Sciences

Non-synonymous single nucleotide polymorphisms in genes for immunoregulatory galectins: Association of galectin-8 (F19Y) occurrence with autoimmune diseases in a Caucasian population

(2012) Zsuzsanna Pál et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Host sialoglycans and bacterial sialidases: a mucosal perspective

(2012) Amanda L. Lewis et al.   CELLULAR MICROBIOLOGY

Tumour suppressor p16INK4a- anoikis-favouring decrease in N/O-glycan/cell surface sialylation by down-regulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model

(2012) Maho Amano et al.   FEBS Journal

Mammalian sialidases: Physiological and pathological roles in cellular functions

(2012) T. Miyagi et al.   GLYCOBIOLOGY

Adhesion/growth-regulatory galectins in the human eye: localization profiles and tissue reactivities as a standard to detect disease-associated alterations

(2012) Ursula Schlötzer-Schrehardt et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Structure and function of collectin liver 1 (CL-L1) and collectin 11 (CL-11, CL-K1)

(2012) Lana Selman et al.   IMMUNOBIOLOGY

Molecular Basis for Protein-specific Transfer ofN-Acetylgalactosamine toN-Linked Glycans by the Glycosyltransferases β1,4-N-Acetylgalactosaminyl Transferase 3 (β4GalNAc-T3) and β4GalNAc-T4

(2012) Dorothy Fiete et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of sulfatide in normal and pathological cells and tissues

(2012) Tadanobu Takahashi et al.   JOURNAL OF LIPID RESEARCH

Ganglioside GM1/Galectin-Dependent Growth Regulation in Human Neuroblastoma Cells: Special Properties of Bivalent Galectin-4 and Significance of Linker Length for Ligand Selection

(2012) Jürgen Kopitz et al.   NEUROCHEMICAL RESEARCH

Functional Analysis of ^|^beta;1,3-N-Acetylglucosaminyltransferases and Regulation of Immunological Function by Polylactosamine

(2012) Akira Togayachi et al.   TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY

Molecular and Structural Basis for Sugar Recognition by Mannose 6-Phosphate Receptor Homology Domain-Containing Lectins and Proteins

(2012) Tadashi Satoh   TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY

Distribution of Sialidase Activity and the Role of Sialidase in the Brain

(2012) Akira Minami et al.   TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY

Toward Comprehensive Analysis of the Galectin Network in Chicken: Unique Diversity of Galectin-3 and Comparison of its Localization Profile in Organs of Adult Animals to the Other Four Members of this Lectin Family

(2011) Herbert Kaltner et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Ribozymes: Flexible molecular devices at work

(2011) Giulia Talini et al.   BIOCHIMIE

Ganglioside GM1 Deficiency in Effector T Cells From NOD Mice Induces Resistance to Regulatory T-Cell Suppression

(2011) G. Wu et al.   DIABETES

Mouse LSECtin as a model for a human Ebola virus receptor

(2011) Z. Pipirou et al.   GLYCOBIOLOGY

Structure and binding analysis of Polyporus squamosus lectin in complex with the Neu5Acα2-6Galβ1-4GlcNAc human-type influenza receptor

(2011) Renuka Kadirvelraj et al.   GLYCOBIOLOGY

Fucose, placental evolution and the glycocode

(2011) J. D. Aplin et al.   GLYCOBIOLOGY

Lectins for histochemical demonstration of glycans

(2011) Jürgen Roth   HISTOCHEMISTRY AND CELL BIOLOGY

Quantitative immunohistochemical fingerprinting of adhesion/growth-regulatory galectins in salivary gland tumours: divergent profiles with diagnostic potential

(2011) Myriam Remmelink et al.   HISTOPATHOLOGY

Human C-type Lectin Domain Family 4, Member C (CLEC4C/BDCA-2/CD303) Is a Receptor for Asialo-galactosyl-oligosaccharides

(2011) Elena Riboldi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome

(2011) Caroline Rooryck et al.   NATURE GENETICS

Comprehensive Analysis of Cellular Galectin-3 Reveals No Consistent Oncogenic Function in Pancreatic Cancer Cells

(2011) Alexander Hann et al.   PLoS One

Comparative analysis reveals selective recognition of glycans by the dendritic cell receptors DC-SIGN and Langerin

(2011) Andrea Holla et al.   PROTEIN ENGINEERING DESIGN & SELECTION

From lectin structure to functional glycomics: principles of the sugar code

(2011) Hans-Joachim Gabius et al.   TRENDS IN BIOCHEMICAL SCIENCES

Functional Diversity of Mammalian Sialyltransferases

(2011) Shou Takashima et al.   TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY

Analysis of SM4 sulfatide as a P-selectin ligand using model membranes

(2010) Dirk Simonis et al.   BIOPHYSICAL CHEMISTRY

Hydrodynamic Properties of Human Adhesion/Growth-Regulatory Galectins Studied by Fluorescence Correlation Spectroscopy

(2010) Antonia Göhler et al.   BIOPHYSICAL JOURNAL

The DC-SIGN family member LSECtin is a novel ligand of CD44 on activated T cells

(2010) Li Tang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tumor suppressor p16INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model

(2010) Hugo Sanchez-Ruderisch et al.   FEBS Journal

SR proteins and galectins: what's in a name?

(2010) K. C. Haudek et al.   GLYCOBIOLOGY

Ganglioside DSGb5, preferred ligand for Siglec-7, inhibits NK cell cytotoxicity against renal cell carcinoma cells

(2010) Y. Kawasaki et al.   GLYCOBIOLOGY

Evolution of CD33-related siglecs: regulating host immune functions and escaping pathogen exploitation?

(2010) Huan Cao et al.   IMMUNOLOGY

How adhesion/growth-regulatory galectins-1 and -3 attain cell specificity: Case study defining their target on neuroblastoma cells (SK-N-MC) and marked affinity regulation by affecting microdomain organization of the membrane

(2010) Jürgen Kopitz et al.   IUBMB LIFE

Protein Flexibility and Conformational Entropy in Ligand Design Targeting the Carbohydrate Recognition Domain of Galectin-3

(2010) Carl Diehl et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dectin-1: a role in antifungal defense and consequences of genetic polymorphisms in humans

(2010) Mohlopheni J. Marakalala et al.   MAMMALIAN GENOME

C-type lectin Langerin is a β-glucan receptor on human Langerhans cells that recognizes opportunistic and pathogenic fungi

(2010) Marein A.W.P. de Jong et al.   MOLECULAR IMMUNOLOGY

Ficolins and FIBCD1: Soluble and membrane bound pattern recognition molecules with acetyl group selectivity

(2010) Theresa Thomsen et al.   MOLECULAR IMMUNOLOGY

The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis

(2010) Emma C Nilsson et al.   NATURE MEDICINE

Molecular basis for peptidoglycan recognition by a bactericidal lectin

(2010) Rebecca E. Lehotzky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recognition of Endogenous Ligands by C-Type Lectins:Interaction of Serum Mannan-binding Protein with Tumor-associated Oligosaccharide Epitopes

(2010) Nobuko Kawasaki et al.   TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY

Two Roles of Mucin Sulfation

(2010) Hiroto Kawashima   TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY

Mammalian Sialidases and Their Functions

(2010) Taeko Miyagi   TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY

Towards Functional Glycomics by Lectin Histochemistry: Strategic Probe Selection to Monitor Core and Branch-end Substitutions and Detection of Cell-type and Regional Selectivity in Adult Mouse Testis and Epididymis

(2010) M. Lohr et al.   ANATOMIA HISTOLOGIA EMBRYOLOGIA

Unique Chicken Tandem-Repeat-Type Galectin: Implications of Alternative Splicing and a Distinct Expression Profile Compared to Those of the Three Proto-Type Proteins

(2009) Herbert Kaltner et al.   BIOCHEMISTRY

From structural to functional glycomics: core substitutions as molecular switches for shape and lectin affinity of N-glycans

(2009) Sabine André et al.   BIOLOGICAL CHEMISTRY

Gangliosides in cell recognition and membrane protein regulation

(2009) Pablo HH Lopez et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Identification of a porcine DC-SIGN-related C-type lectin, porcine CLEC4G (LSECtin), and its order of intron removal during splicing: Comparative genomic analyses of the cluster of genes CD23/CLEC4G/DC-SIGN among mammalian species

(2009) Y.W. Huang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Mannose phosphorylation in health and disease

(2009) Katrin Kollmann et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Fine tuning of cell functions through remodeling of glycosphingolipids by plasma membrane-associated glycohydrolases

(2009) Sandro Sonnino et al.   FEBS LETTERS

Highly fucosylated N-glycan ligands for mannan-binding protein expressed specifically on CD26 (DPPVI) isolated from a human colorectal carcinoma cell line, SW1116

(2009) N. Kawasaki et al.   GLYCOBIOLOGY

The second bovine  -galactoside- 2,6-sialyltransferase (ST6Gal II): genomic organization and stimulation of its in vitro expression by IL-6 in bovine mammary epithelial cells

(2009) B. Laporte et al.   GLYCOBIOLOGY

Tyrosine Kinase Activity of Epidermal Growth Factor Receptor Is Regulated by GM3 Binding through Carbohydrate to Carbohydrate Interactions

(2009) Nagako Kawashima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational entropy changes upon lactose binding to the carbohydrate recognition domain of galectin-3

(2009) Carl Diehl et al.   JOURNAL OF BIOMOLECULAR NMR

Mincle is a long sought receptor for mycobacterial cord factor

(2009) Isamu Matsunaga et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

(2009) Eri Ishikawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cross-Linking of GM1 Ganglioside by Galectin-1 Mediates Regulatory T Cell Activity Involving TRPC5 Channel Activation: Possible Role in Suppressing Experimental Autoimmune Encephalomyelitis

(2009) J. Wang et al.   JOURNAL OF IMMUNOLOGY

Galectin-4-Regulated Delivery of Glycoproteins to the Brush Border Membrane of Enterocyte-Like Cells

(2009) Laurence Stechly et al.   TRAFFIC

Tracing the development of Structural Elucidation of N-glycans

(2009) Lee Yuan Chuan   TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY

Prototype chicken galectins revisited: characterization of a third protein with distinctive hydrodynamic behaviour and expression pattern in organs of adult animals

(2008) Herbert Kaltner et al.   BIOCHEMICAL JOURNAL

Glycosphingolipid behaviour in complex membranes

(2008) Alessandro Prinetti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The Asn19Lys Substitution in the Osteoclast Inhibitory Lectin (OCIL) Gene is Associated with a Reduction of Bone Mineral Density in Postmenopausal Women

(2008) Begoña Pineda et al.   CALCIFIED TISSUE INTERNATIONAL

Porcine DC-SIGN: Molecular cloning, gene structure, tissue distribution and binding characteristics

(2008) Y.W. Huang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Lgals6, a 2-Million-Year-Old Gene in Mice: A Case of Positive Darwinian Selection and Presence/Absence Polymorphism

(2008) D. Houzelstein et al.   GENETICS

A discontinuous hammerhead ribozyme embedded in a mammalian messenger RNA

(2008) Monika Martick et al.   NATURE

The Ashwell receptor mitigates the lethal coagulopathy of sepsis

(2008) Prabhjit K Grewal et al.   NATURE MEDICINE

Identification of a receptor required for the anti-inflammatory activity of IVIG

(2008) R. M. Anthony et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Implications of Siglec-5-Mediated Sialoglycan Recognition

(2007) Marina A. Zhuravleva et al.   JOURNAL OF MOLECULAR BIOLOGY