Mechanisms of site‐specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits

PP2A‐B56 binds to Apc1 and promotes Cdc20 association with the APC/C ubiquitin ligase in mitosis

(2019) Kazuyuki Fujimitsu et al.   EMBO REPORTS

A Consensus Binding Motif for the PP4 Protein Phosphatase

(2019) Yumi Ueki et al.   MOLECULAR CELL

ADAM17 is required for EGF-R–induced intestinal tumors via IL-6 trans-signaling

(2018) Stefanie Schmidt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Ebola Virus Nucleoprotein Recruits the Host PP2A-B56 Phosphatase to Activate Transcriptional Support Activity of VP30

(2018) Thomas Kruse et al.   MOLECULAR CELL

Homing in: Mechanisms of Substrate Targeting by Protein Kinases

(2018) Chad J. Miller et al.   TRENDS IN BIOCHEMICAL SCIENCES

Protein phosphatases in the regulation of mitosis

(2018) Jakob Nilsson   JOURNAL OF CELL BIOLOGY

The PP2AB56phosphatase promotes the association of Cdc20 with APC/C in mitosis

(2017) Sun Joo Lee et al.   JOURNAL OF CELL SCIENCE

PP2A Cdc55 Phosphatase Imposes Ordered Cell-Cycle Phosphorylation by Opposing Threonine Phosphorylation

(2017) Molly Godfrey et al.   MOLECULAR CELL

An Attachment-Independent Biochemical Timer of the Spindle Assembly Checkpoint

(2017) Junbin Qian et al.   MOLECULAR CELL

Distinct kinetics of serine and threonine dephosphorylation are essential for mitosis

(2017) Jamin B. Hein et al.   NATURE CELL BIOLOGY

Genome editing using FACS enrichment of nuclease-expressing cells and indel detection by amplicon analysis

(2017) Lindsey A Lonowski et al.   Nature Protocols

PP2A-B′ holoenzyme substrate recognition, regulation and role in cytokinesis

(2017) Cheng-Guo Wu et al.   Cell Discovery

PP2A as a master regulator of the cell cycle

(2016) Nathan Wlodarchak et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit

(2016) Michael J. Cundell et al.   JOURNAL OF CELL BIOLOGY

A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase

(2016) Emil Peter Thrane Hertz et al.   MOLECULAR CELL

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Expanding the PP2A Interactome by Defining a B56-Specific SLiM

(2016) Xinru Wang et al.   STRUCTURE

WGE: a CRISPR database for genome engineering: Fig. 1.

(2015) Alex Hodgkins et al.   BIOINFORMATICS

Optimized Sleeping Beauty transposons rapidly generate stable transgenic cell lines

(2015) Eric Kowarz et al.   Biotechnology Journal

Global Phosphoproteomic Mapping of Early Mitotic Exit in Human Cells Identifies Novel Substrate Dephosphorylation Motifs

(2015) Rachael A. McCloy et al.   MOLECULAR & CELLULAR PROTEOMICS

Optimized Sleeping Beauty transposons rapidly generate stable transgenic cell lines

(2015) Eric Kowarz et al.   Biotechnology Journal

MultiNotch MS3 Enables Accurate, Sensitive, and Multiplexed Detection of Differential Expression across Cancer Cell Line Proteomes

(2014) Graeme C. McAlister et al.   ANALYTICAL CHEMISTRY

A1 adenosine receptor–stimulated exocytosis in bladder umbrella cells requires phosphorylation of ADAM17 Ser-811 and EGF receptor transactivation

(2014) H. Sandeep Prakasam et al.   MOLECULAR BIOLOGY OF THE CELL

Novel Parallelized Quadrupole/Linear Ion Trap/Orbitrap Tribrid Mass Spectrometer Improving Proteome Coverage and Peptide Identification Rates

(2013) Michael W. Senko et al.   ANALYTICAL CHEMISTRY

Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression

(2013) T. Kruse et al.   JOURNAL OF CELL SCIENCE

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

EGF Receptor Is Required for KRAS-Induced Pancreatic Tumorigenesis

(2012) Christine M. Ardito et al.   CANCER CELL

Integration of Kinase and Phosphatase Activities by BUBR1 Ensures Formation of Stable Kinetochore-Microtubule Attachments

(2012) Saskia J.E. Suijkerbuijk et al.   DEVELOPMENTAL CELL

Comet: An open-source MS/MS sequence database search tool

(2012) Jimmy K. Eng et al.   PROTEOMICS

Rapid and Reproducible Single-Stage Phosphopeptide Enrichment of Complex Peptide Mixtures: Application to General and Phosphotyrosine-Specific Phosphoproteomics Experiments

(2011) Arminja N. Kettenbach et al.   ANALYTICAL CHEMISTRY

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase

(2011) Emily A. Foley et al.   NATURE CELL BIOLOGY

MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics

(2011) Lily Ting et al.   NATURE METHODS

MassChroQ: A versatile tool for mass spectrometry quantification

(2011) Benoît Valot et al.   PROTEOMICS

Protein Phosphatase 2A Reactivates FOXO3a through a Dynamic Interplay with 14-3-3 and AKT

(2010) Amrik Singh et al.   MOLECULAR BIOLOGY OF THE CELL

Direct Activation of TACE-Mediated Ectodomain Shedding by p38 MAP Kinase Regulates EGF Receptor-Dependent Cell Proliferation

(2010) Pinglong Xu et al.   MOLECULAR CELL

The Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A

(2010) A. Gharbi-Ayachi et al.   SCIENCE

Greatwall Phosphorylates an Inhibitor of Protein Phosphatase 2A That Is Essential for Mitosis

(2010) S. Mochida et al.   SCIENCE

Molecular Determinants for PP2A Substrate Specificity: Charged Residues Mediate Dephosphorylation of Tyrosine Hydroxylase by the PP2A/B′ Regulatory Subunit

(2009) Amit Saraf et al.   BIOCHEMISTRY

From Promiscuity to Precision: Protein Phosphatases Get a Makeover

(2009) David M. Virshup et al.   MOLECULAR CELL

Improved visualization of protein consensus sequences by iceLogo

(2009) Niklaas Colaert et al.   NATURE METHODS

Protein phosphatase 2A regulatory subunits and cancer

(2008) Pieter J.A. Eichhorn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Structure of a Protein Phosphatase 2A Holoenzyme: Insights into B55-Mediated Tau Dephosphorylation

(2008) Yanhui Xu et al.   MOLECULAR CELL

STRING 8--a global view on proteins and their functional interactions in 630 organisms

(2008) L. J. Jensen et al.   NUCLEIC ACIDS RESEARCH