Extracellular Vesicle-Mediated Delivery of CircSCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models

Loss of Super-Enhancer-Regulated circRNA Nfix Induces Cardiac Regeneration After Myocardial Infarction in Adult Mice

(2019) Senlin Huang et al.   CIRCULATION

Circular RNA TLK1 aggravates neuronal injury and neurological deficits after ischemic stroke via miR-335-3p/TIPARP

(2019) Fangfang Wu et al.   JOURNAL OF NEUROSCIENCE

Gene Therapy

(2019) Katherine A. High et al.   NEW ENGLAND JOURNAL OF MEDICINE

The biogenesis, biology and characterization of circular RNAs

(2019) Lasse S. Kristensen et al.   NATURE REVIEWS GENETICS

Circular RNA NF1-419 enhances autophagy to ameliorate senile dementia by binding Dynamin-1 and Adaptor protein 2 B1 in AD-like mice

(2019) Chen Diling et al.   Aging-US

Large animal models of stroke and traumatic brain injury as translational tools

(2018) Annabel Jain Sorby-Adams et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition

(2018) Li Yang et al.   Autophagy

Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke

(2018) Bing Han et al.   Autophagy

RSRC1 mutation affects intellect and behaviour through aberrant splicing and transcription, downregulating IGFBP3

(2018) Yonatan Perez et al.   BRAIN

Peripheral immune cells infiltrate into sites of secondary neurodegeneration after ischemic stroke

(2018) K.A. Jones et al.   BRAIN BEHAVIOR AND IMMUNITY

FACS isolation of endothelial cells and pericytes from mouse brain microregions

(2018) Elizabeth E Crouch et al.   Nature Protocols

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Circular RNA and its mechanisms in disease: From the bench to the clinic

(2018) Bing Han et al.   PHARMACOLOGY & THERAPEUTICS

CRMP2-binding compound, edonerpic maleate, accelerates motor function recovery from brain damage

(2018) Hiroki Abe et al.   SCIENCE

Exosome Therapy for Stroke

(2018) Jieli Chen et al.   STROKE

Recent advancements in the use of exosomes as drug delivery systems

(2018) Edwin J. Bunggulawa et al.   JOURNAL OF NANOBIOTECHNOLOGY

Anti-ACSA-2 defines a novel monoclonal antibody for prospective isolation of living neonatal and adult astrocytes

(2017) Christina G. Kantzer et al.   GLIA

Opening a New Time Window for Treatment of Stroke by Targeting HDAC2

(2017) Yu-Hui Lin et al.   JOURNAL OF NEUROSCIENCE

Role of primary motor cortex in the control of manual dexterity assessed via sequential bilateral lesion in the adult macaque monkey: A case study

(2017) Julie Savidan et al.   NEUROSCIENCE

TRRUST v2: an expanded reference database of human and mouse transcriptional regulatory interactions

(2017) Heonjong Han et al.   NUCLEIC ACIDS RESEARCH

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function

(2017) Monika Piwecka et al.   SCIENCE

MicroRNA-17–92 Cluster in Exosomes Enhance Neuroplasticity and Functional Recovery After Stroke in Rats

(2017) Hongqi Xin et al.   STROKE

A pilot study on transient ischemic stroke induced with endothelin-1 in the rhesus monkeys

(2017) PeiMin Dai et al.   Scientific Reports

Exosome Mediated Delivery of miR-124 Promotes Neurogenesis after Ischemia

(2017) Jialei Yang et al.   Molecular Therapy-Nucleic Acids

Exosomes in stroke pathogenesis and therapy

(2016) Zheng Gang Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

The next step in translational research: lessons learned from the first preclinical randomized controlled trial

(2016) Gemma Llovera et al.   JOURNAL OF NEUROCHEMISTRY

Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2

(2016) William W. Du et al.   NUCLEIC ACIDS RESEARCH

MECP2 disorders: from the clinic to mice and back

(2015) Laura Marie Lombardi et al.   JOURNAL OF CLINICAL INVESTIGATION

GDF10 is a signal for axonal sprouting and functional recovery after stroke

(2015) Songlin Li et al.   NATURE NEUROSCIENCE

Neuroprotection for ischaemic stroke: Current status and challenges

(2015) Antonio Moretti et al.   PHARMACOLOGY & THERAPEUTICS

Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia

(2015) Gemma Llovera et al.   Science Translational Medicine

Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery

(2014) Gemma Llovera et al.   Jove-Journal of Visualized Experiments

How to produce personality neuroscience research with high statistical power and low additional cost

(2013) Raymond A. Mar et al.   COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE

Creb1-Mecp2-mCpG Complex Transactivates Postnatal Murine Neuronal Glucose Transporter Isoform 3 Expression

(2013) Yongjun Chen et al.   ENDOCRINOLOGY

SMTP-7, a Novel Small-Molecule Thrombolytic for Ischemic Stroke: A Study in Rodents and Primates

(2013) Hironobu Sawada et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Inhibition of a SNARE-Sensitive Pathway in Astrocytes Attenuates Damage following Stroke

(2013) D. J. Hines et al.   JOURNAL OF NEUROSCIENCE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation

(2013) Yichuan Xiao et al.   NATURE MEDICINE

A New Non-Human Primate Model of Photochemically Induced Cerebral Infarction

(2013) Satoshi Ikeda et al.   PLoS One

MiR-133b Promotes Neural Plasticity and Functional Recovery After Treatment of Stroke with Multipotent Mesenchymal Stromal Cells in Rats Via Transfer of Exosome-Enriched Extracellular Particles

(2013) Hongqi Xin et al.   STEM CELLS

The Rett Syndrome Protein MeCP2 Regulates Synaptic Scaling

(2012) Z. Qiu et al.   JOURNAL OF NEUROSCIENCE

Systemically administered human bone marrow-derived mesenchymal stem home into peripheral organs but do not induce neuroprotective effects in the MCAo-mouse model for cerebral ischemia

(2012) Barbara Steiner et al.   NEUROSCIENCE LETTERS

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Neuroplasticity in the context of motor rehabilitation after stroke

(2011) Michael A. Dimyan et al.   Nature Reviews Neurology

Genome-Wide Activity-Dependent MeCP2 Phosphorylation Regulates Nervous System Development and Function

(2011) Sonia Cohen et al.   NEURON

Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke

(2010) Andrew N. Clarkson et al.   NATURE

Functional testing in a mouse stroke model induced by occlusion of the distal middle cerebral artery

(2009) Judith Lubjuhn et al.   JOURNAL OF NEUROSCIENCE METHODS

Plasticity during stroke recovery: from synapse to behaviour

(2009) Timothy H. Murphy et al.   NATURE REVIEWS NEUROSCIENCE

ABC/2 for rapid clinical estimate of infarct, perfusion, and mismatch volumes

(2009) J. R. Sims et al.   NEUROLOGY

Mecp2-Null Mice Provide New Neuronal Targets for Rett Syndrome

(2008) Rocio G. Urdinguio et al.   PLoS One