Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia
出版年份 2015 全文链接
标题
Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia
作者
关键词
-
出版物
Science Translational Medicine
Volume 7, Issue 299, Pages 299ra121-299ra121
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2015-08-06
DOI
10.1126/scitranslmed.aaa9853
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke
- (2014) Jens Neumann et al. ACTA NEUROPATHOLOGICA
- Increasing value and reducing waste in research design, conduct, and analysis
- (2014) John P A Ioannidis et al. LANCET
- Preclinical research: Make mouse studies work
- (2014) Steve Perrin NATURE
- Journals unite for reproducibility
- (2014) M. McNutt SCIENCE
- Changing the Mindset in Life Sciences Toward Translation: A Consensus
- (2014) G. N. Duda et al. Science Translational Medicine
- Are We Ready to Translate T-Cell Transmigration in Stroke?
- (2014) Wolf-Rüdiger Schäbitz et al. STROKE
- Blocking of α4 Integrin Does Not Protect From Acute Ischemic Stroke in Mice
- (2014) Friederike Langhauser et al. STROKE
- Distinguishing between Exploratory and Confirmatory Preclinical Research Will Improve Translation
- (2014) Jonathan Kimmelman et al. PLOS BIOLOGY
- Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery
- (2014) Gemma Llovera et al. Jove-Journal of Visualized Experiments
- Immune Cell Infiltration in Malignant Middle Cerebral Artery Infarction: Comparison with Transient Cerebral Ischemia
- (2013) Hannah X Chu et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Bringing rigour to translational medicine
- (2013) David W. Howells et al. Nature Reviews Neurology
- Power failure: why small sample size undermines the reliability of neuroscience
- (2013) Katherine S. Button et al. NATURE REVIEWS NEUROSCIENCE
- Genomic responses in mouse models poorly mimic human inflammatory diseases
- (2013) Junhee Seok et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Concerted Appeal for International Cooperation in Preclinical Stroke Research
- (2013) Ulrich Dirnagl et al. STROKE
- Guidelines for the Early Management of Patients With Acute Ischemic Stroke
- (2013) Edward C. Jauch et al. STROKE
- Evaluation of Excess Significance Bias in Animal Studies of Neurological Diseases
- (2013) Konstantinos K. Tsilidis et al. PLOS BIOLOGY
- Postischemic Brain Infiltration of Leukocyte Subpopulations Differs among Murine Permanent and Transient Focal Cerebral Ischemia Models
- (2012) Wei Zhou et al. BRAIN PATHOLOGY
- Targeting Mannose-Binding Lectin Confers Long-Lasting Protection With a Surprisingly Wide Therapeutic Window in Cerebral Ischemia
- (2012) Franca Orsini et al. CIRCULATION
- Improving the Efficiency of the Development of Drugs for Stroke
- (2012) David W. Howells et al. International Journal of Stroke
- International, Multicenter Randomized Preclinical Trials in Translational Stroke Research: It's Time to Act
- (2012) Ulrich Dirnagl et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- The Two Pathophysiologies of Focal Brain Ischemia: Implications for Translational Stroke Research
- (2012) Konstantin-Alexander Hossmann JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Assessing Post-Stroke Behavior in Mouse Models of Focal Ischemia
- (2012) Mustafa Balkaya et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Raise standards for preclinical cancer research
- (2012) C. Glenn Begley et al. NATURE
- The immunology of acute stroke
- (2012) Ángel Chamorro et al. Nature Reviews Neurology
- Natalizumab
- (2012) Richard Rudick et al. JAMA Neurology
- Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke
- (2011) Arthur Liesz et al. BRAIN
- Development of an NIH Consortium for PreclinicAl AssESsment of CARdioprotective Therapies (CAESAR): A Paradigm Shift in Studies of Infarct Size Limitation
- (2011) David J. Lefer et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS
- Improving the efficacy of translational medicine by optimally integrating health care, academia and industry
- (2011) Stefan R Bornstein et al. NATURE MEDICINE
- Stroke research at a crossroad: asking the brain for directions
- (2011) Costantino Iadecola et al. NATURE NEUROSCIENCE
- Believe it or not: how much can we rely on published data on potential drug targets?
- (2011) Florian Prinz et al. NATURE REVIEWS DRUG DISCOVERY
- Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation
- (2010) C. Kleinschnitz et al. BLOOD
- Brain Protection: Maybe Yes, Maybe No
- (2010) M. A. Moskowitz STROKE
- Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research
- (2010) Carol Kilkenny et al. PLOS BIOLOGY
- Emulating Multicentre Clinical Stroke Trials: A New Paradigm for Studying Novel Interventions in Experimental Models of Stroke
- (2009) P. M. W. Bath et al. International Journal of Stroke
- Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury
- (2009) Takashi Shichita et al. NATURE MEDICINE
- The adhesive removal test: a sensitive method to assess sensorimotor deficits in mice
- (2009) Valentine Bouet et al. Nature Protocols
- The blood–brain and the blood–cerebrospinal fluid barriers: function and dysfunction
- (2009) Britta Engelhardt et al. Seminars in Immunopathology
- Improving Outcome after Stroke: Overcoming the Translational Roadblock
- (2008) Matthias Endres et al. CEREBROVASCULAR DISEASES
- Stroke
- (2008) Geoffrey A Donnan et al. LANCET
- Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke
- (2008) Werner Hacke et al. NEW ENGLAND JOURNAL OF MEDICINE
- Empirical Evidence of Bias in the Design of Experimental Stroke Studies
- (2008) Nicolas A. Crossley et al. STROKE
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started