Simplified Murine 3D Neuronal Cultures for Investigating Neuronal Activity and Neurodegeneration

3D compartmented model to study the neurite-related toxicity of Aβ aggregates included in collagen gels of adaptable porosity

(2016) Marie-Noëlle Labour et al.   Acta Biomaterialia

Clinical Trials in a Dish: The Potential of Pluripotent Stem Cells to Develop Therapies for Neurodegenerative Diseases

(2016) Kelly M. Haston et al.   Annual Review of Pharmacology and Toxicology

Novel scalable 3D cell based model for in vitro neurotoxicity testing: Combining human differentiated neurospheres with gene expression and functional endpoints

(2015) Ana Paula Terrasso et al.   JOURNAL OF BIOTECHNOLOGY

Differentiation of neuroepithelial stem cells into functional dopaminergic neurons in 3D microfluidic cell culture

(2015) Edinson Lucumi Moreno et al.   LAB ON A CHIP

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

(2015) Anca M Paşca et al.   NATURE METHODS

From 2D to 3D: novel nanostructured scaffolds to investigate signalling in reconstructed neuronal networks

(2015) Susanna Bosi et al.   Scientific Reports

The prion protein regulates beta-amyloid-mediated self-renewal of neural stem cells in vitro

(2015) Steven J Collins et al.   Stem Cell Research & Therapy

MEK1 transduces the prion protein N2 fragment antioxidant effects

(2014) C. L. Haigh et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A three-dimensional human neural cell culture model of Alzheimer’s disease

(2014) Se Hoon Choi et al.   NATURE

Generation of cerebral organoids from human pluripotent stem cells

(2014) Madeline A Lancaster et al.   Nature Protocols

Astrocyte-Secreted Matricellular Proteins in CNS Remodelling during Development and Disease

(2014) Emma V. Jones et al.   NEURAL PLASTICITY

Cytosolic caspases mediate mislocalised SOD2 depletion in an in vitro model of chronic prion infection

(2013) L. Sinclair et al.   Disease Models & Mechanisms

Scalable alignment of three-dimensional cellular constructs in a microfluidic chip

(2013) Chukwuemeka George Anene-Nzelu et al.   LAB ON A CHIP

Efficient neuronal differentiation and maturation of human pluripotent stem cells encapsulated in 3D microfibrous scaffolds

(2012) Hong Fang Lu et al.   BIOMATERIALS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Three Dimensional Neuronal Cell Cultures More Accurately Model Voltage Gated Calcium Channel Functionality in Freshly Dissected Nerve Tissue

(2012) Yinzhi Lai et al.   PLoS One

Induced Tauopathy in a Novel 3D-Culture Model Mediates Neurodegenerative Processes: A Real-Time Study on Biochips

(2012) Diana Seidel et al.   PLoS One

Acute exposure to prion infection induces transient oxidative stress progressing to be cumulatively deleterious with chronic propagation in vitro

(2011) Cathryn L. Haigh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Optical Imaging Detects Apoptosis in the Brain and Peripheral Organs of Prion-Infected Mice

(2011) Simon C. Drew et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Concise Review: Quiescent and Active States of Endogenous Adult Neural Stem Cells: Identification and Characterization

(2011) Ya-Zhou Wang et al.   STEM CELLS

Near-Infrared Fluorescence Imaging of Apoptotic Neuronal Cell Death in a Live Animal Model of Prion Disease

(2010) Victoria A. Lawson et al.   ACS Chemical Neuroscience

Quiescent and Active Hippocampal Neural Stem Cells with Distinct Morphologies Respond Selectively to Physiological and Pathological Stimuli and Aging

(2010) Sebastian Lugert et al.   Cell Stem Cell

Prion infection of differentiated neurospheres

(2010) Maria Eugenia Herva et al.   JOURNAL OF NEUROSCIENCE METHODS

3D cell culture opens new dimensions in cell-based assays

(2008) Bradley A. Justice et al.   DRUG DISCOVERY TODAY

Mouse-adapted sporadic human Creutzfeldt–Jakob disease prions propagate in cell culture

(2008) Victoria A. Lawson et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY