The prion protein regulates beta-amyloid-mediated self-renewal of neural stem cells in vitro

Temporal dynamics of hippocampal neurogenesis in chronic neurodegeneration

(2014) Diego Gomez-Nicola et al.   BRAIN

N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits

(2013) Yvonne Bouter et al.   ACTA NEUROPATHOLOGICA

Intrahippocampal injection of Aβ1-42inhibits neurogenesis and down-regulates IFN-γ and NF-κB expression in hippocampus of adult mouse brain

(2013) Meige Zheng et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Cytosolic caspases mediate mislocalised SOD2 depletion in an in vitro model of chronic prion infection

(2013) L. Sinclair et al.   Disease Models & Mechanisms

Prion Protein-mediated Toxicity of Amyloid-β Oligomers Requires Lipid Rafts and the Transmembrane LRP1

(2013) Jo V. Rushworth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proliferation, differentiation and amyloid-β production in neural progenitor cells isolated from TgCRND8 mice

(2013) S. Kanemoto et al.   NEUROSCIENCE

Prion Protein Is Decreased in Alzheimer's Brain and Inversely Correlates with BACE1 Activity, Amyloid-β Levels and Braak Stage

(2013) Isobel J. Whitehouse et al.   PLoS One

The Complex PrPc-Fyn Couples Human Oligomeric A  with Pathological Tau Changes in Alzheimer's Disease

(2012) M. Larson et al.   JOURNAL OF NEUROSCIENCE

Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β

(2012) Justin M. Nussbaum et al.   NATURE

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

(2012) Ji Won Um et al.   NATURE NEUROSCIENCE

A  neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptors

(2012) H. You et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overlapping profiles of Abeta peptides in the Alzheimer's disease and pathological aging brains

(2012) Brenda D Moore et al.   Alzheimers Research & Therapy

Acute exposure to prion infection induces transient oxidative stress progressing to be cumulatively deleterious with chronic propagation in vitro

(2011) Cathryn L. Haigh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer’s disease

(2010) Erik Portelius et al.   ACTA NEUROPATHOLOGICA

Expression and knockdown of cellular prion protein (PrPC) in differentiating mouse embryonic stem cells

(2010) Oscar A. Peralta et al.   DIFFERENTIATION

Treatment with normal prion protein delays differentiation and helps to maintain high proliferation activity in human embryonic stem cells

(2010) Young Jin Lee et al.   JOURNAL OF NEUROCHEMISTRY

Memory Impairment in Transgenic Alzheimer Mice Requires Cellular Prion Protein

(2010) D. A. Gimbel et al.   JOURNAL OF NEUROSCIENCE

PrPC-related signal transduction is influenced by copper, membrane integrity and the alpha cleavage site

(2009) Cathryn L Haigh et al.   CELL RESEARCH

Neurogenesis and Alzheimer's disease: At the crossroads

(2009) Orly Lazarov et al.   EXPERIMENTAL NEUROLOGY

The Caenorhabditis elegans Aβ1–42Model of Alzheimer Disease Predominantly Expresses Aβ3–42

(2009) Gawain McColl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior

(2008) Dennis J. Selkoe   BEHAVIOURAL BRAIN RESEARCH