Structural and functional properties of proteins interacting with small heat shock proteins

Cellular Handling of Protein Aggregates by Disaggregation Machines

(2018) Axel Mogk et al.   MOLECULAR CELL

Identification of proteins interacting with the mitochondrial small heat shock protein Hsp22 of Drosophila melanogaster: Implication in mitochondrial homeostasis

(2018) Afrooz Dabbaghizadeh et al.   PLoS One

It takes a dimer to tango: Oligomeric small heat shock proteins dissociate to capture substrate

(2018) Indu Santhanagopalan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recombinant small heat shock protein from Acholeplasma laidlawii increases the Escherichia coli viability in thermal stress by selective protein rescue

(2017) A. R. Kayumov et al.   MOLECULAR BIOLOGY

Substrates of the chloroplast small heat shock proteins 22E/F point to thermolability as a regulative switch for heat acclimation in Chlamydomonas reinhardtii

(2017) Mark Rütgers et al.   PLANT MOLECULAR BIOLOGY

Changes in Drosophila mitochondrial proteins following chaperone-mediated lifespan extension confirm a role of Hsp22 in mitochondrial UPR and reveal a mitochondrial localization for cathepsin D

(2016) Geneviève Morrow et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding

(2016) Sophia Ungelenk et al.   Nature Communications

The Interplay Between Respiratory Supercomplexes and ROS in Aging

(2015) Maria Luisa Genova et al.   ANTIOXIDANTS & REDOX SIGNALING

Drosophila melanogaster mitochondrial Hsp22: a role in resistance to oxidative stress, aging and the mitochondrial unfolding protein response

(2015) Geneviève Morrow et al.   BIOGERONTOLOGY

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

(2015) Dirk M. Walther et al.   CELL

Medical implications of understanding the functions of human small heat shock proteins

(2015) Evgeny V Mymrikov et al.   Expert Review of Proteomics

A First Line of Stress Defense: Small Heat Shock Proteins and Their Function in Protein Homeostasis

(2015) Martin Haslbeck et al.   JOURNAL OF MOLECULAR BIOLOGY

Protein sHSP26 improves chloroplast performance under heat stress by interacting with specific chloroplast proteins in maize (Zea mays)

(2015) Xiuli Hu et al.   Journal of Proteomics

The Chaperone Activity of the Developmental Small Heat Shock Protein Sip1 Is Regulated by pH-Dependent Conformational Changes

(2015) Tilly Fleckenstein et al.   MOLECULAR CELL

A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis

(2015) Margit Fuchs et al.   PLoS Genetics

Heat Shock Protein 22 (Hsp22) Regulates Oxidative Phosphorylation upon Its Mitochondrial Translocation with the Inducible Nitric Oxide Synthase in Mammalian Heart

(2015) Eman Rashed et al.   PLoS One

Chaperone-independent mitochondrial translocation and protection by αB-crystallin in RPE cells

(2013) Rebecca S. McGreal et al.   EXPERIMENTAL EYE RESEARCH

One size does not fit all: The oligomeric states of αB crystallin

(2013) Scott P. Delbecq et al.   FEBS LETTERS

Phenotype of Cardiomyopathy in Cardiac-specific Heat Shock Protein B8 K141N Transgenic Mouse

(2013) Atsushi Sanbe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small Heat Shock Protein IbpB Acts as a Robust Chaperone in Living Cells by Hierarchically Activating Its Multi-type Substrate-binding Residues

(2013) Xinmiao Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In VivoSubstrate Diversity and Preference of Small Heat Shock Protein IbpB as Revealed by Using a Genetically Incorporated Photo-cross-linker

(2013) Xinmiao Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Different anti-aggregation and pro-degradative functions of the members of the mammalian sHSP family in neurological disorders

(2013) S. Carra et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Analysis and Phylogeny of Small Heat Shock Proteins from Marine Viruses and Their Cyanobacteria Host

(2013) Halim Maaroufi et al.   PLoS One

Multilevel structural characteristics for the natural substrate proteins of bacterial small heat shock proteins

(2013) Xinmiao Fu et al.   PROTEIN SCIENCE

Apoptosis of osteosarcoma cultures by the combination of the cyclin-dependent kinase inhibitor SCH727965 and a heat shock protein 90 inhibitor

(2013) W Fu et al.   Cell Death & Disease

Regulation of Lifespan by the Mitochondrial Electron Transport Chain: Reactive Oxygen Species-Dependent and Reactive Oxygen Species-Independent Mechanisms

(2012) Filippo Scialo et al.   ANTIOXIDANTS & REDOX SIGNALING

αB-crystallin/sHSP protects cytochrome c and mitochondrial function against oxidative stress in lens and retinal cells

(2012) Rebecca S. McGreal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Alternative bacterial two-component small heat shock protein systems

(2012) A. Bepperling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H11 Kinase/Heat Shock Protein 22 Deletion Impairs Both Nuclear and Mitochondrial Functions of STAT3 and Accelerates the Transition Into Heart Failure on Cardiac Overload

(2011) Hongyu Qiu et al.   CIRCULATION

Small Heat-Shock Protein HSPB1 Mutants Stabilize Microtubules in Charcot-Marie-Tooth Neuropathy

(2011) L. Almeida-Souza et al.   JOURNAL OF NEUROSCIENCE

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

Small heat shock proteins and α-crystallins: dynamic proteins with flexible functions

(2011) Eman Basha et al.   TRENDS IN BIOCHEMICAL SCIENCES

Independent evolution of the core domain and its flanking sequences in small heat shock proteins

(2010) Thomas Kriehuber et al.   FASEB JOURNAL

The Heat Shock Response: Life on the Verge of Death

(2010) Klaus Richter et al.   MOLECULAR CELL

Cellular strategies for controlling protein aggregation

(2010) Jens Tyedmers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Biological and Chemical Approaches to Diseases of Proteostasis Deficiency

(2009) Evan T. Powers et al.   Annual Review of Biochemistry

Identification of the key structural motifs involved in HspB8/HspB6–Bag3 interaction

(2009) Margit Fuchs et al.   BIOCHEMICAL JOURNAL

Substrate binding site flexibility of the small heat shock protein molecular chaperones

(2009) N. Jaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein misfolding and disease: from the test tube to the organism

(2008) Leila M Luheshi et al.   CURRENT OPINION IN CHEMICAL BIOLOGY