Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia

标题
Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia
作者
关键词
acute myeloid leukemia, differentiation, HoxA9, high-throughput screen, phenotypic screen, leukemia-initiating cell, dihydroorotate dehydrogenase, brequinar, metabolic inhibitor
出版物
CELL
Volume 167, Issue 1, Pages 171-186.e15
出版商
Elsevier BV
发表日期
2016-09-16
DOI
10.1016/j.cell.2016.08.057

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