Inferring the role of the microbiome on survival in patients treated with immune checkpoint inhibitors: causal modeling, timing, and classes of concomitant medications

Tim-3/galectin-9 pathway and mMDSC control primary and secondary resistances to PD-1 blockade in lung cancer patients

(2019) Emeric Limagne et al.   OncoImmunology

Antibiotics are associated with decreased progression-free survival of advanced melanoma patients treated with immune checkpoint inhibitors

(2019) Arielle Elkrief et al.   OncoImmunology

A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma

(2019) Alexander C. Huang et al.   NATURE MEDICINE

Antibiotics are associated with attenuated efficacy of anti-PD-1/PD-L1 therapies in Chinese patients with advanced non-small cell lung cancer

(2019) Sha Zhao et al.   LUNG CANCER

Association of Prior Antibiotic Treatment With Survival and Response to Immune Checkpoint Inhibitor Therapy in Patients With Cancer

(2019) David J. Pinato et al.   JAMA Oncology

The effect of antibiotics on clinical outcomes in immune-checkpoint blockade: a systematic review and meta-analysis of observational studies

(2019) Brooke E. Wilson et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Negative association of antibiotics on clinical activity of immune checkpoint inhibitors in patients with advanced renal cell and non-small-cell lung cancer

(2018) L Derosa et al.   ANNALS OF ONCOLOGY

Rheumatic manifestations among cancer patients treated with immune checkpoint inhibitors

(2018) Merav Lidar et al.   AUTOIMMUNITY REVIEWS

Chronic glucocorticoid treatment induced circadian clock disorder leads to lipid metabolism and gut microbiota alterations in rats

(2018) Tao Wu et al.   LIFE SCIENCES

The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients

(2018) Vyara Matson et al.   SCIENCE

Impact of Baseline Steroids on Efficacy of Programmed Cell Death-1 and Programmed Death-Ligand 1 Blockade in Patients With Non–Small-Cell Lung Cancer

(2018) Kathryn C. Arbour et al.   JOURNAL OF CLINICAL ONCOLOGY

Extensive impact of non-antibiotic drugs on human gut bacteria

(2018) Lisa Maier et al.   NATURE

DrugBank 5.0: a major update to the DrugBank database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

(2017) V. Gopalakrishnan et al.   SCIENCE

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

(2017) Bertrand Routy et al.   SCIENCE

The yin and yang of leukotriene B 4 mediated inflammation in cancer

(2017) Venkatakrishna R. Jala et al.   SEMINARS IN IMMUNOLOGY

Microbiome and Anticancer Immunosurveillance

(2016) Laurence Zitvogel et al.   CELL

The influence of non-steroidal anti-inflammatory drugs on the gut microbiome

(2016) M.A.M. Rogers et al.   CLINICAL MICROBIOLOGY AND INFECTION

Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade

(2016) P.-L. Chen et al.   Cancer Discovery

Recurrent antibiotic exposure may promote cancer formation – Another step in understanding the role of the human microbiota?

(2015) Ben Boursi et al.   EUROPEAN JOURNAL OF CANCER

Proton pump inhibitors affect the gut microbiome

(2015) Floris Imhann et al.   GUT

Proton pump inhibitors alter the composition of the gut microbiota

(2015) Matthew A Jackson et al.   GUT

Using Corticosteroids to Reshape the Gut Microbiome

(2015) Edmond Y. Huang et al.   INFLAMMATORY BOWEL DISEASES

Regularization Paths for Generalized Linear Models via Coordinate Descent

(2015) Jerome Friedman et al.   Journal of Statistical Software

Regularization Paths for Cox's Proportional Hazards Model via Coordinate Descent

(2015) Noah Simon et al.   Journal of Statistical Software

Gut Dysbiosis Promotes M2 Macrophage Polarization and Allergic Airway Inflammation via Fungi-Induced PGE2

(2014) Yun-Gi Kim et al.   Cell Host & Microbe

The impact of anti-inflammatory agents on the outcome of patients with colorectal cancer

(2013) J.H. Park et al.   CANCER TREATMENT REVIEWS

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

Gut microbiota disturbance during antibiotic therapy: a multi-omic approach

(2012) Ana Elena Pérez-Cobas et al.   GUT

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

Non-steroidal anti-inflammatory drugs, tumour immunity and immunotherapy

(2012) Muzammal Hussain et al.   PHARMACOLOGICAL RESEARCH

Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation

(2010) L. Dethlefsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Research electronic data capture (REDCap)—A metadata-driven methodology and workflow process for providing translational research informatics support

(2008) Paul A. Harris et al.   JOURNAL OF BIOMEDICAL INFORMATICS

The Charlson comorbidity index is adapted to predict costs of chronic disease in primary care patients

(2008) Mary E. Charlson et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY