High glucose-induced hyperosmolarity contributes to COX-2 expression and angiogenesis: implications for diabetic retinopathy

NA+/H+ Exchanger 1-and Aquaporin-1-Dependent Hyperosmolarity Changes Decrease Nitric Oxide Production and Induce VCAM-1 Expression in Endothelial Cells Exposed to High Glucose

(2017) R. Madonna et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Aflibercept, bevacizumab and ranibizumab prevent glucose-induced damage in human retinal pericytes in vitro, through a PLA2/COX-2/VEGF-A pathway

(2015) Giovanni Giurdanella et al.   BIOCHEMICAL PHARMACOLOGY

Plasma levels of matrix metalloproteinase-2, -3, -10, and tissue inhibitor of metalloproteinase-1 are associated with vascular complications in patients with type 1 diabetes: the EURODIAB Prospective Complications Study

(2015) Stijn A Peeters et al.   Cardiovascular Diabetology

Beneficial effects of fenofibric acid on overexpression of extracellular matrix components, COX-2, and impairment of endothelial permeability associated with diabetic retinopathy

(2015) Sumon Roy et al.   EXPERIMENTAL EYE RESEARCH

High glucose-induced hyperosmolarity impacts proliferation, cytoskeleton remodeling and migration of human induced pluripotent stem cells via aquaporin-1

(2014) Rosalinda Madonna et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Tonicity-responsive enhancer binding protein regulates the expression of aldose reductase and protein kinase C δ in a mouse model of diabetic retinopathy

(2014) Jeongsook Park et al.   EXPERIMENTAL EYE RESEARCH

Role of phospholipases A2 in diabetic retinopathy: In vitro and in vivo studies

(2013) Gabriella Lupo et al.   BIOCHEMICAL PHARMACOLOGY

Cellular and molecular mechanisms of vascular injury in diabetes — Part I: Pathways of vascular disease in diabetes

(2011) Rosalinda Madonna et al.   VASCULAR PHARMACOLOGY

CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response

(2010) Takeshi Maruyama et al.   EMBO JOURNAL

Hypertonicity-Induced Expression of Monocyte Chemoattractant Protein-1 through a Novel Cis-Acting Element and MAPK Signaling Pathways

(2010) R. Kojima et al.   JOURNAL OF IMMUNOLOGY

Non-viral siRNA delivery into the mouse retina in vivo

(2010) Andrey Turchinovich et al.   BMC Ophthalmology

Polyoma Virus-Induced Osteosarcomas in Inbred Strains of Mice: Host Determinants of Metastasis

(2010) Palanivel Velupillai et al.   PLoS Pathogens

Hypertonic induction of COX2 expression requires TonEBP/NFAT5 in renal epithelial cells

(2009) N.O. Favale et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Roles of a prostaglandin E-type receptor, EP3, in upregulation of matrix metalloproteinase-9 and vascular endothelial growth factor during enhancement of tumor metastasis

(2009) Hideki Amano et al.   CANCER SCIENCE

COX-2, VEGF and tumour angiogenesis

(2009) D.P. Toomey et al.   SURGEON-JOURNAL OF THE ROYAL COLLEGES OF SURGEONS OF EDINBURGH AND IRELAND

Aquaporin 1 is required for hypoxia-inducible angiogenesis in human retinal vascular endothelial cells

(2008) Kentaro Kaneko et al.   MICROVASCULAR RESEARCH

10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes

(2008) Rury R. Holman et al.   NEW ENGLAND JOURNAL OF MEDICINE