Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer
出版年份 2016 全文链接
标题
Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer
作者
关键词
-
出版物
CARCINOGENESIS
Volume 38, Issue 1, Pages 2-11
出版商
Oxford University Press (OUP)
发表日期
2016-11-10
DOI
10.1093/carcin/bgw118
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- DNA Hypomethylation and Histone Variant macroH2A1 Synergistically Attenuate Chemotherapy-Induced Senescence to Promote Hepatocellular Carcinoma Progression
- (2016) M. Borghesan et al. CANCER RESEARCH
- Systemic Chromosome Instability Resulted in Colonic Transcriptomic Changes in Metabolic, Proliferation, and Stem Cell Regulators in Sgo1-/+ Mice
- (2016) C. V. Rao et al. CANCER RESEARCH
- Variable Intra-Tumor Genomic Heterogeneity of Multiple Lesions in Patients With Hepatocellular Carcinoma
- (2016) Ruidong Xue et al. GASTROENTEROLOGY
- Mutation of cancer driverMLL2results in transcription stress and genome instability
- (2016) Theodoros Kantidakis et al. GENES & DEVELOPMENT
- Genetic profiling of hepatocellular carcinoma using next-generation sequencing
- (2016) Kornelius Schulze et al. JOURNAL OF HEPATOLOGY
- High rates of chromosome missegregation suppress tumor progression but do not inhibit tumor initiation
- (2016) Lauren M. Zasadil et al. MOLECULAR BIOLOGY OF THE CELL
- Emerging links among Chromosome Instability (CIN), cancer, and aging
- (2016) Chinthalapally V. Rao et al. MOLECULAR CARCINOGENESIS
- Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor
- (2016) Adrien Decorsière et al. NATURE
- Replication fork stability confers chemoresistance in BRCA-deficient cells
- (2016) Arnab Ray Chaudhuri et al. NATURE
- NOTCH1 mediates a switch between two distinct secretomes during senescence
- (2016) Matthew Hoare et al. NATURE CELL BIOLOGY
- Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer
- (2016) Akihiro Fujimoto et al. NATURE GENETICS
- Current status and perspectives of immune-based therapies for hepatocellular carcinoma
- (2016) Maridi Aerts WORLD JOURNAL OF GASTROENTEROLOGY
- Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination
- (2016) Tongchao Li et al. PLoS Genetics
- Systemic chromosome instability in Shugoshin-1 mice resulted in compromised glutathione pathway, activation of Wnt signaling and defects in immune system in the lung
- (2016) H Y Yamada et al. Oncogenesis
- Tumor-promoting/progressing role of additional chromosome instability in hepatic carcinogenesis in Sgo1 (Shugoshin 1) haploinsufficient mice
- (2015) Hiroshi Y. Yamada et al. CARCINOGENESIS
- Temporal Trends of Nonalcoholic Fatty Liver Disease–Related Hepatocellular Carcinoma in the Veteran Affairs Population
- (2015) Sahil Mittal et al. Clinical Gastroenterology and Hepatology
- Hepatocellular Carcinoma From Epidemiology to Prevention: Translating Knowledge into Practice
- (2015) Amit G. Singal et al. Clinical Gastroenterology and Hepatology
- Heterogeneity of hepatocellular carcinoma contributes to cancer progression
- (2015) Kuo-Shyang Jeng et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Genetic Landscape and Biomarkers of Hepatocellular Carcinoma
- (2015) Jessica Zucman-Rossi et al. GASTROENTEROLOGY
- World-wide relative contribution of hepatitis B and C viruses in hepatocellular carcinoma
- (2015) Catherine de Martel et al. HEPATOLOGY
- Chromothripsis from DNA damage in micronuclei
- (2015) Cheng-Zhong Zhang et al. NATURE
- Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets
- (2015) Kornelius Schulze et al. NATURE GENETICS
- Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis
- (2015) Jiyuan Zhang et al. NATURE MEDICINE
- The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development
- (2015) Ana Ortega-Molina et al. NATURE MEDICINE
- Genetic and epigenetic aspects of initiation and progression of hepatocellular carcinoma
- (2015) Mitsuro Kanda WORLD JOURNAL OF GASTROENTEROLOGY
- Understanding the MIG6-EGFR Signaling Axis in Lung Tumorigenesis
- (2015) E. Izumchenko et al. Cancer Discovery
- Sgo1 is a potential therapeutic target for hepatocellular carcinoma
- (2015) Lyu-Han Wang et al. Oncotarget
- Hepatocyte-Specific Arid1a Deficiency Initiates Mouse Steatohepatitis and Hepatocellular Carcinoma
- (2015) Jia-Zhu Fang et al. PLoS One
- KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation
- (2015) Changcun Guo et al. Oncotarget
- The historical Coffin-Lowry syndrome family revisited: Identification of two novel mutations ofRPS6KA3in three male patients
- (2014) Hiromi Koso Nishimoto et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Senescent cells: SASPected drivers of age-related pathologies
- (2014) Yossi Ovadya et al. BIOGERONTOLOGY
- Exome sequencing reveals frequent inactivating mutations inARID1A, ARID1B, ARID2andARID4Ain microsatellite unstable colorectal cancer
- (2014) Tatiana Cajuso et al. INTERNATIONAL JOURNAL OF CANCER
- Hepatocyte senescence induced by radiation and partial hepatectomy in rat liver
- (2014) Maria Paola Serra et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Identification of prognostic biomarkers in hepatitis B virus-related hepatocellular carcinoma and stratification by integrative multi-omics analysis
- (2014) Ruoyu Miao et al. JOURNAL OF HEPATOLOGY
- A Role for H3K4 Monomethylation in Gene Repression and Partitioning of Chromatin Readers
- (2014) Jemmie Cheng et al. MOLECULAR CELL
- Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
- (2014) Marco Gerlinger et al. NATURE GENETICS
- DNA-Damage Response during Mitosis Induces Whole-Chromosome Missegregation
- (2014) S. F. Bakhoum et al. Cancer Discovery
- Does bromodomain flexibility influence histone recognition?
- (2013) Sandra Steiner et al. FEBS LETTERS
- Replication stress links structural and numerical cancer chromosomal instability
- (2013) Rebecca A. Burrell et al. NATURE
- The causes and consequences of genetic heterogeneity in cancer evolution
- (2013) Rebecca A. Burrell et al. NATURE
- Signatures of mutational processes in human cancer
- (2013) Ludmil B. Alexandrov et al. NATURE
- Genetics and epigenetics of liver cancer
- (2013) Cigdem Ozen et al. New Biotechnology
- Whole chromosome instability resulting from the synergistic effects of pRB and p53 inactivation
- (2013) A L Manning et al. ONCOGENE
- Ribosomal S6 Kinase 2 (RSK2) Maintains Genomic Stability by Activating the Atm/p53-Dependent DNA Damage Pathway
- (2013) Han Chi Lim et al. PLoS One
- -Catenin induces T-cell transformation by promoting genomic instability
- (2013) M. Dose et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors
- (2013) A. D. Silk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genomic Instability and Colon Carcinogenesis: From the Perspective of Genes
- (2013) Chinthalapally V. Rao et al. Frontiers in Oncology
- Next generation sequencing reveals genetic landscape of hepatocellular carcinomas
- (2012) Shuyu Li et al. CANCER LETTERS
- The DNA damage checkpoint protein ATM promotes hepatocellular apoptosis and fibrosis in a mouse model of non-alcoholic fatty liver disease
- (2012) Erin K. Daugherity et al. CELL CYCLE
- BMP, Wnt and FGF signals are integrated through evolutionarily conserved enhancers to achieve robust expression of Pax3 and Zic genes at the zebrafish neural plate border
- (2012) A. T. Garnett et al. DEVELOPMENT
- Nrf2 knockout enhances intestinal tumorigenesis inApcmin/+mice due to attenuation of anti-oxidative stress pathway while potentiates inflammation
- (2012) Ka Lung Cheung et al. MOLECULAR CARCINOGENESIS
- Exome sequencing of hepatitis B virus–associated hepatocellular carcinoma
- (2012) Jian Huang et al. NATURE GENETICS
- Genomic landscape of liver cancer
- (2012) Zemin Zhang NATURE GENETICS
- Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators
- (2012) Akihiro Fujimoto et al. NATURE GENETICS
- Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
- (2012) Marco Gerlinger et al. NEW ENGLAND JOURNAL OF MEDICINE
- Transcriptional consequences of aneuploidy
- (2012) J. M. Sheltzer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mad2 Is a Critical Mediator of the Chromosome Instability Observed upon Rb and p53 Pathway Inhibition
- (2011) Juan-Manuel Schvartzman et al. CANCER CELL
- Molecular classification of hepatocellular carcinoma anno 2011
- (2011) H. van Malenstein et al. EUROPEAN JOURNAL OF CANCER
- Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stability
- (2011) Cornelia Meisenberg et al. NUCLEIC ACIDS RESEARCH
- Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data
- (2011) Y. Tao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expression of ZIC family genes in meningiomas and other brain tumors
- (2010) Jun Aruga et al. BMC CANCER
- Proliferation of aneuploid human cells is limited by a p53-dependent mechanism
- (2010) Sarah L. Thompson et al. JOURNAL OF CELL BIOLOGY
- Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal
- (2010) Rocio Sotillo et al. NATURE
- The p16INK4A tumor suppressor regulates cellular oxidative stress
- (2010) N C Jenkins et al. ONCOGENE
- Enhanced genomic instabilities caused by deregulated microtubule dynamics and chromosome segregation: a perspective from genetic studies in mice
- (2009) C. V. Rao et al. CARCINOGENESIS
- Increased chromosome instability dramatically disrupts neural genome integrity and mediates cerebellar degeneration in the ataxia-telangiectasia brain
- (2009) Ivan Y. Iourov et al. HUMAN MOLECULAR GENETICS
- A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4
- (2009) J. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Studying chromosome instability in the mouse
- (2008) Floris Foijer et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Sonic Hedgehog signaling impairs ionizing radiation–induced checkpoint activation and induces genomic instability
- (2008) Jennifer M. Leonard et al. JOURNAL OF CELL BIOLOGY
- HBV X protein targets hBubR1, which induces dysregulation of the mitotic checkpoint
- (2008) S Kim et al. ONCOGENE
- Whole chromosome instability and cancer: a complex relationship
- (2008) Robin M. Ricke et al. TRENDS IN GENETICS
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