WNK1-OSR1 kinase-mediated phospho-activation of Na+-K+-2Cl- cotransporter facilitates glioma migration

Inhibition of PI3K/AKT/mTOR Pathway Enhances Temozolomide-Induced Cytotoxicity in Pituitary Adenoma Cell Lines in Vitro and Xenografted Pituitary Adenoma in Female Nude Mice

(2013) Congxin Dai et al.   ENDOCRINOLOGY

Cellular distribution of NKCC2 in the gastric mucosa and its response to short-term osmotic shock

(2012) T. Ji et al.   CELL AND TISSUE RESEARCH

Inhibition of Na+-K+-2Cl–Cotransporter isoform 1 Accelerates Temozolomidemediated Apoptosis in Glioblastoma Cancer Cells

(2012) Jehad Algharabil et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Differential Expression of 2',3'-Cyclic-Nucleotide 3'-Phosphodiesterase and Neural Lineage Markers Correlate with Glioblastoma Xenograft Infiltration and Patient Survival

(2012) M. Zorniak et al.   CLINICAL CANCER RESEARCH

NF-κB is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug

(2012) Simona Caporali et al.   Journal of Translational Medicine

Regulation of Brain Tumor Dispersal by NKCC1 Through a Novel Role in Focal Adhesion Regulation

(2012) Tomas Garzon-Muvdi et al.   PLOS BIOLOGY

With-No-Lysine Kinase 3 (WNK3) stimulates glioma invasion by regulating cell volume

(2011) Brian R. Haas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Ion channels and tranporters in cancer. 2. Ion channels and the control of cancer cell migration

(2011) Vishnu Anand Cuddapah et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation

(2011) Jacob O. Thastrup et al.   BIOCHEMICAL JOURNAL

The WNKs: Atypical Protein Kinases With Pleiotropic Actions

(2011) James A. McCormick et al.   PHYSIOLOGICAL REVIEWS

WNK1 is required for mitosis and abscission

(2011) S.-w. Tu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging role for ERM proteins in cell adhesion and migration

(2011) Monique Arpin et al.   Cell Adhesion & Migration

Phosphoregulation of the Na–K–2Cl and K–Cl cotransporters by the WNK kinases

(2010) Kristopher T. Kahle et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Inhibition of the Sodium-Potassium-Chloride Cotransporter Isoform-1 Reduces Glioma Invasion

(2010) B. R. Haas et al.   CANCER RESEARCH

A key role for membrane transporter NKCC1 in mediating chondrocyte volume increase in the mammalian growth plate

(2010) Peter G Bush et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure

(2009) Akihito Ohta et al.   HUMAN MOLECULAR GENETICS

LINGO-1 Interacts with WNK1 to Regulate Nogo-induced Inhibition of Neurite Extension

(2009) Zhaohuan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA Repair and Resistance of Gliomas to Chemotherapy and Radiotherapy

(2009) G. Frosina   MOLECULAR CANCER RESEARCH

The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway

(2008) C. Richardson et al.   JOURNAL OF CELL SCIENCE

Na+,K+,2Cl− Cotransport and Intracellular Chloride Regulation in Rat Primary Sensory Neurons: Thermodynamic and Kinetic Aspects

(2008) Héctor I. Rocha-González et al.   JOURNAL OF NEUROPHYSIOLOGY

AKT Is Activated in an Ataxia-Telangiectasia and Rad3-Related-Dependent Manner in Response to Temozolomide and Confers Protection against Drug-Induced Cell Growth Inhibition

(2008) S. Caporali et al.   MOLECULAR PHARMACOLOGY

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE