GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment
出版年份 2019 全文链接
标题
GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment
作者
关键词
-
出版物
Science Immunology
Volume 4, Issue 42, Pages eaax8189
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2019-12-14
DOI
10.1126/sciimmunol.aax8189
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer
- (2018) Wei Li et al. Cell Metabolism
- The Immune Landscape of Cancer
- (2018) Vésteinn Thorsson et al. IMMUNITY
- Integrating single-cell transcriptomic data across different conditions, technologies, and species
- (2018) Andrew Butler et al. NATURE BIOTECHNOLOGY
- Apoptotic cell–induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans
- (2018) Rahul Shinde et al. NATURE IMMUNOLOGY
- The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages
- (2018) Bence Daniel et al. NUCLEIC ACIDS RESEARCH
- PTPN2 Regulates Inflammasome Activation and Controls Onset of Intestinal Inflammation and Colon Cancer
- (2018) Marianne R. Spalinger et al. Cell Reports
- Inhibition of GCN2 sensitizes ASNS-low cancer cells to asparaginase by disrupting the amino acid response
- (2018) Akito Nakamura et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Macrophage Immunometabolism: Where Are We (Going)?
- (2017) Jan Van den Bossche et al. TRENDS IN IMMUNOLOGY
- Glycolysis regulates the expansion of myeloid-derived suppressor cells in tumor-bearing hosts through prevention of ROS-mediated apoptosis
- (2017) Shiou-Ling Jian et al. Cell Death & Disease
- Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade
- (2016) Joseph L. Benci et al. CELL
- The integrated stress response
- (2016) Karolina Pakos‐Zebrucka et al. EMBO REPORTS
- The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation
- (2016) Rajesh Ravindran et al. NATURE
- Regulation of the T Cell Response by CD39
- (2016) Maisa C. Takenaka et al. TRENDS IN IMMUNOLOGY
- Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards
- (2016) Vincenzo Bronte et al. Nature Communications
- Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis
- (2015) Jacob H. Levine et al. CELL
- Metabolic Reprogramming of Immune Cells in Cancer Progression
- (2015) Subhra K. Biswas IMMUNITY
- Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways
- (2015) Irene Mattiola et al. JOURNAL OF IMMUNOLOGY
- Robust enumeration of cell subsets from tissue expression profiles
- (2015) Aaron M Newman et al. NATURE METHODS
- The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity
- (2015) Buvana Ravishankar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stable inhibitory activity of regulatory T cells requires the transcription factor Helios
- (2015) H.-J. Kim et al. SCIENCE
- Tumor-Associated Macrophages: From Mechanisms to Therapy
- (2014) Roy Noy et al. IMMUNITY
- ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R–mediated apoptosis
- (2014) Thomas Condamine et al. JOURNAL OF CLINICAL INVESTIGATION
- Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
- (2014) Oscar R. Colegio et al. NATURE
- GCN2 regulates the CCAAT enhancer binding protein beta and hepatic gluconeogenesis
- (2013) Xu Xu et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
- (2013) Jaeseok Han et al. NATURE CELL BIOLOGY
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Amino acid catabolism: a pivotal regulator of innate and adaptive immunity
- (2012) Tracy L. McGaha et al. IMMUNOLOGICAL REVIEWS
- Differential oestrogen receptor binding is associated with clinical outcome in breast cancer
- (2012) Caryn S. Ross-Innes et al. NATURE
- Macrophage Expression of Hypoxia-Inducible Factor-1 Suppresses T-Cell Function and Promotes Tumor Progression
- (2010) A. L. Doedens et al. CANCER RESEARCH
- The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation
- (2010) Jiangbin Ye et al. EMBO JOURNAL
- Tumor-Induced Tolerance and Immune Suppression Depend on the C/EBPβ Transcription Factor
- (2010) Ilaria Marigo et al. IMMUNITY
- Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation
- (2010) Hongxia Z. Imtiyaz et al. JOURNAL OF CLINICAL INVESTIGATION
- HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
- (2010) Cesar A. Corzo et al. JOURNAL OF EXPERIMENTAL MEDICINE
- L-Arginine Deprivation Regulates Cyclin D3 mRNA Stability in Human T Cells by Controlling HuR Expression
- (2010) P. C. Rodriguez et al. JOURNAL OF IMMUNOLOGY
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- Tumor-Associated Macrophages and Survival in Classic Hodgkin's Lymphoma
- (2010) Christian Steidl et al. NEW ENGLAND JOURNAL OF MEDICINE
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
- (2009) Linda Madisen et al. NATURE NEUROSCIENCE
- Model-based Analysis of ChIP-Seq (MACS)
- (2008) Yong Zhang et al. GENOME BIOLOGY
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