The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation

The Varieties of Immunological Experience: Of Pathogens, Stress, and Dendritic Cells

(2015) Bali Pulendran   Annual Review of Immunology

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

(2015) Jennifer Martinez et al.   NATURE CELL BIOLOGY

Phosphorylation of eIF2α Is Dispensable for Differentiation but Required at a Posttranscriptional Level for Paneth Cell Function and Intestinal Homeostasis in Mice

(2014) Stewart S. Cao et al.   INFLAMMATORY BOWEL DISEASES

The eIF2α kinases: their structures and functions

(2013) Neysan Donnelly et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Vaccine Activation of the Nutrient Sensor GCN2 in Dendritic Cells Enhances Antigen Presentation

(2013) R. Ravindran et al.   SCIENCE

Amino Acid Starvation Induced by Invasive Bacterial Pathogens Triggers an Innate Host Defense Program

(2012) Ivan Tattoli et al.   Cell Host & Microbe

Surgical Stress Resistance Induced by Single Amino Acid Deprivation Requires Gcn2 in Mice

(2012) W. Peng et al.   Science Translational Medicine

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Human nutrition, the gut microbiome and the immune system

(2011) Andrew L. Kau et al.   NATURE

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Translation Attenuation through eIF2α Phosphorylation Prevents Oxidative Stress and Maintains the Differentiated State in β Cells

(2009) Sung Hoon Back et al.   Cell Metabolism

Beneficial effects of a low-protein diet on host resistance to Paracoccidioides brasiliensis in mice

(2009) Motoko Oarada et al.   NUTRITION

Halofuginone Inhibits TH17 Cell Differentiation by Activating the Amino Acid Starvation Response

(2009) M. S. Sundrud et al.   SCIENCE

Functional characterisation of decoy receptor 3 in Crohn's disease

(2008) B Funke et al.   GUT

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE

Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease

(2008) Subra Kugathasan et al.   NATURE GENETICS

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

(2008) Troy D Querec et al.   NATURE IMMUNOLOGY