Functional Compartmentalization of HSP60-Survivin Interaction between Mitochondria and Cytosol in Cancer Cells

CCAR2/DBC1 and Hsp60 Positively Regulate Expression of Survivin in Neuroblastoma Cells

(2019) Wootae Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Deletion of heat shock protein 60 in adult mouse cardiomyocytes perturbs mitochondrial protein homeostasis and causes heart failure

(2019) Feifei Fan et al.   CELL DEATH AND DIFFERENTIATION

An Inhibitor of the Interaction of Survivin with Smac in Mitochondria Promotes Apoptosis

(2019) Seong‐Hyun Park et al.   Chemistry-An Asian Journal

Targeting HSP60 by subcutaneous injections of jetPEI/HSP60-shRNA destabilizes cytoplasmic survivin and inhibits hepatocellular carcinoma growth

(2018) Ya-Hui Huang et al.   MOLECULAR CARCINOGENESIS

Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth

(2018) Chao Zhou et al.   Cell Death & Disease

The novel prognostic marker, EHMT2, is involved in cell proliferation via HSPD1 regulation in breast cancer

(2018) Seon‑Kyu Kim et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

CCAR2 Is Required for Proliferation and Tumor Maintenance in Human Squamous Cell Carcinoma

(2017) Sarah A. Best et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Elevated sodium leads to the increased expression of HSP60 and induces apoptosis in HUVECs

(2017) Bojana Jakic et al.   PLoS One

Survivin downregulation using siRNA nanoliposomes inhibits cell proliferation and promotes the apoptosis of MHCC-97H hepatic cancer cells: An in vitro and in vivo study

(2017) Ziqin Liu et al.   Oncology Letters

Survivin: a unique target for tumor therapy

(2016) Himani Garg et al.   Cancer Cell International

The N-terminus of survivin is a mitochondrial-targeting sequence and Src regulator

(2016) Lucia Dunajová et al.   JOURNAL OF CELL SCIENCE

The tumor promoting roles of HSP60 and HIF2α in gastric cancer cells

(2016) Wei-Wei Tong et al.   TUMOR BIOLOGY

A novel crosstalk between CCAR2 and AKT pathway in the regulation of cancer cell proliferation

(2016) Michela Restelli et al.   Cell Death & Disease

Survivin and Tumorigenesis: Molecular Mechanisms and Therapeutic Strategies

(2016) Xun Chen et al.   Journal of Cancer

Down-regulation of HSP60 Suppresses the Proliferation of Glioblastoma Cells via the ROS/AMPK/mTOR Pathway

(2016) Haiping Tang et al.   Scientific Reports

The Functional Repertoire of Survivin's Tails

(2015) Sally P Wheatley   CELL CYCLE

Neonatal Death and Heart Failure in Mouse with Transgenic HSP60 Expression

(2015) Tsung-Hsien Chen et al.   Biomed Research International

Silencing of Survivin Expression Leads to Reduced Proliferation and Cell Cycle Arrest in Cancer Cells

(2015) Yuhuan Li et al.   Journal of Cancer

Tumor suppressor XAF1 induces apoptosis, inhibits angiogenesis and inhibits tumor growth in hepatocellular carcinoma

(2015) Li Ming Zhu et al.   Oncotarget

Survivin as a Preferential Target for Cancer Therapy

(2014) Mahsa Mobahat et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cytosolic Hsp60 Can Modulate Proteasome Activity in Yeast

(2014) Bella Kalderon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Silencing survivin expression inhibits the tumor growth of non-small-cell lung cancer cells in vitro and in vivo

(2014) KEJIAN ZHANG et al.   Molecular Medicine Reports

Heat Shock Protein 60 Overexpression Is Associated with the Progression and Prognosis in Gastric Cancer

(2014) Xiao-shan Li et al.   PLoS One

HSP60 Predicts Survival in Advanced Serous Ovarian Cancer

(2013) Elisabet Hjerpe et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Mitochondrial Heat Shock Protein-90 Modulates Vascular Smooth Muscle Cell Survival and the Vascular Injury Response in Vivo

(2012) Andrew W. Hoel et al.   AMERICAN JOURNAL OF PATHOLOGY

Identification and verification of heat shock protein 60 as a potential serum marker for colorectal cancer

(2011) Céline Hamelin et al.   FEBS Journal

Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

(2011) Ronan J Kelly et al.   Molecular Cancer

High expression of survivin predicts poor prognosis in esophageal squamous cell carcinoma following radiotherapy

(2011) Hongxia Zhu et al.   TUMOR BIOLOGY

Hsp60 expression, new locations, functions, and perspectives for cancer diagnosis and therapy

(2010) Francesco Cappello et al.   CANCER BIOLOGY & THERAPY

Heat Shock Protein 60 Regulation of the Mitochondrial Permeability Transition Pore in Tumor Cells

(2010) J. C. Ghosh et al.   CANCER RESEARCH

Cytosolic Hsp60 Is Involved in the NF-κB-Dependent Survival of Cancer Cells via IKK Regulation

(2010) Jung Nyeo Chun et al.   PLoS One

Immunohistochemical Expression of Hsp60 Correlates With Tumor Progression and Hormone Resistance in Prostate Cancer

(2010) Carolina Castilla et al.   UROLOGY

Knockdown of survivin expression by siRNAs enhances chemosensitivity of prostate cancer cells and attenuates its tumorigenicity

(2009) J. Shen et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Interaction between HSP60 and β-catenin promotes metastasis

(2009) Ya-Ping Tsai et al.   CARCINOGENESIS

Restoration of XAF1 expression induces apoptosis and inhibits tumor growth in gastric cancer

(2009) Shui Ping Tu et al.   INTERNATIONAL JOURNAL OF CANCER

Heat Shock Protein 60, via MyD88 Innate Signaling, Protects B Cells from Apoptosis, Spontaneous and Induced

(2009) M. Cohen-Sfady et al.   JOURNAL OF IMMUNOLOGY

Expression of Heat Shock Protein 60 kDa Is Upregulated in Cervical Cancer

(2009) You Jin Hwang et al.   YONSEI MEDICAL JOURNAL

Survivin: Key Regulator of Mitosis and Apoptosis and Novel Target for Cancer Therapeutics

(2008) A. C. Mita et al.   CLINICAL CANCER RESEARCH

Proteomics-Based Identification of HSP60 as a Tumor-Associated Antigen in Early Stage Breast Cancer and Ductal Carcinomain situ

(2008) C. Desmetz et al.   JOURNAL OF PROTEOME RESEARCH