Xuebijing Injection Alleviates Pam3CSK4-Induced Inflammatory Response and Protects Mice From Sepsis Caused by Methicillin-Resistant Staphylococcus aureus

Bacterial lipolysis of immune-activating ligands promotes evasion of innate defenses

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XueBiJing Injection Versus Placebo for Critically Ill Patients With Severe Community-Acquired Pneumonia

(2019) Yuanlin Song et al.   CRITICAL CARE MEDICINE

SIRS in the Time of Sepsis-3

(2018) Steven Q. Simpson   CHEST

Curcumin attenuates sepsis-induced acute organ dysfunction by preventing inflammation and enhancing the suppressive function of Tregs

(2018) Longwang Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop

(2018) Zhiyong Liu et al.   Nature Communications

Hydroxysafflor yellow A (HSYA) targeting NF-κB and MAPK pathways ameliorates the development of osteoarthritis

(2018) Zhichao Hu et al.   Food & Function

Antiseptic Activity of Ethnomedicinal Xuebijing Revealed by the Metabolomics Analysis Using UHPLC-Q-Orbitrap HRMS

(2018) Lihua Zuo et al.   Frontiers in Pharmacology

Scutellarin Suppresses NLRP3 Inflammasome Activation in Macrophages and Protects Mice against Bacterial Sepsis

(2018) Yi Liu et al.   Frontiers in Pharmacology

Clinical implications of the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2018) Shannon M. Fernando et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

PI3K/Akt/mTOR signaling pathway participates in Streptococcus uberis-induced inflammation in mammary epithelial cells in concert with the classical TLRs/NF-ĸB pathway

(2018) Bin Li et al.   VETERINARY MICROBIOLOGY

Unlocking the potential of natural products in drug discovery

(2018) Gerard D. Wright   Microbial Biotechnology

Paeoniflorin Ameliorates Atherosclerosis by Suppressing TLR4-Mediated NF-κB Activation

(2017) Huan Li et al.   INFLAMMATION

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

(2017) Andrew Rhodes et al.   INTENSIVE CARE MEDICINE

Host-directed therapies for bacterial and viral infections

(2017) Stefan H. E. Kaufmann et al.   NATURE REVIEWS DRUG DISCOVERY

Advances in the understanding and treatment of sepsis-induced immunosuppression

(2017) Fabienne Venet et al.   Nature Reviews Nephrology

Cytokine storm and sepsis disease pathogenesis

(2017) Benjamin G. Chousterman et al.   Seminars in Immunopathology

Paeoniflorin prevents TLR2/4-mediated inflammation in type 2 diabetic nephropathy

(2017) Tingmin Zhang et al.   BioScience Trends

Xuebijing injection attenuates pulmonary injury by reducing oxidative stress and proinflammatory damage in rats with heat stroke

(2017) Yi Chen et al.   Experimental and Therapeutic Medicine

Chemical profiling and quantification of XueBiJing injection, a systematic quality control strategy using UHPLC-Q Exactive hybrid quadrupole-orbitrap high-resolution mass spectrometry

(2017) Zhi Sun et al.   Scientific Reports

Hydroxysafflor Yellow A Attenuates the Apoptosis of Peripheral Blood CD4+ T Lymphocytes in a Murine Model of Sepsis

(2017) Jinping Wang et al.   Frontiers in Pharmacology

Methicillin-resistant Staphylococcus aureus (MRSA): burden of disease and control challenges in Europe

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Micheliolide provides protection of mice against Staphylococcus aureus and MRSA infection by down-regulating inflammatory response

(2017) Xinru Jiang et al.   Scientific Reports

Pharmacokinetics and disposition of monoterpene glycosides derived from Paeonia lactiflora roots (Chishao) after intravenous dosing of antiseptic XueBiJing injection in human subjects and rats

(2016) Chen Cheng et al.   ACTA PHARMACOLOGICA SINICA

Immunotherapeutic implications of IL-6 blockade for cytokine storm

(2016) Toshio Tanaka et al.   Immunotherapy

Effects of Xuebijing injection on microcirculation in septic shock

(2016) Liang Wang et al.   JOURNAL OF SURGICAL RESEARCH

Host-directed therapies for infectious diseases: current status, recent progress, and future prospects

(2016) Alimuddin Zumla et al.   LANCET INFECTIOUS DISEASES

Sepsis: pathophysiology and clinical management

(2016) Jeffrey E Gotts et al.   BMJ-British Medical Journal

Sepsis: pathophysiology and clinical management

(2016) Jeffrey E Gotts et al.   BMJ-British Medical Journal

Xuebijing injection reduces organ injuries and improves survival by attenuating inflammatory responses and endothelial injury in heatstroke mice

(2015) Qiulin Xu et al.   BMC Complementary and Alternative Medicine

Cost-Effectiveness of Strategies to Prevent Methicillin-Resistant Staphylococcus aureus Transmission and Infection in an Intensive Care Unit

(2015) Courtney A. Gidengil et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Paeoniflorin diminishes ConA-induced IL-8 production in primary human hepatic sinusoidal endothelial cells in the involvement of ERK1/2 and Akt phosphorylation

(2015) Wen-Guang Gong et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cytokine profile in severe gram-positive and gram-negative abdominal sepsis

(2015) Maja Surbatovic et al.   Scientific Reports

Traditional Chinese Medicine Xuebijing Treatment Is Associated with Decreased Mortality Risk of Patients with Moderate Paraquat Poisoning

(2015) Ping Gong et al.   PLoS One

Treatment Effects of Xuebijing Injection in Severe Septic Patients with Disseminated Intravascular Coagulation

(2014) Qin Yin et al.   Evidence-based Complementary and Alternative Medicine

Clinical Management ofStaphylococcus aureusBacteremia

(2014) Thomas L. Holland et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

GSK3β and the control of infectious bacterial diseases

(2014) Huizhi Wang et al.   TRENDS IN MICROBIOLOGY

Severe Sepsis and Septic Shock

(2013) Derek C. Angus et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of the major constituents in Xuebijing injection by HPLC-ESI-MS

(2011) Hao Huang et al.   PHYTOCHEMICAL ANALYSIS

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Immunology in China: the past, present and future

(2008) Xuetao Cao   NATURE IMMUNOLOGY

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL