Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype
出版年份 2019 全文链接
标题
Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype
作者
关键词
-
出版物
Clinical Epigenetics
Volume 11, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-12-02
DOI
10.1186/s13148-019-0763-5
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Immunotherapy of Primary Brain Tumors: Facts and Hopes
- (2018) Robin A Buerki et al. CLINICAL CANCER RESEARCH
- Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in glioma stem cells and glioblastoma
- (2018) Rajendra P. Pangeni et al. Epigenetics
- Disruptor of telomeric silencing 1-like (DOT1L): disclosing a new class of non-nucleoside inhibitors by means of ligand-based and structure-based approaches
- (2018) Manuela Sabatino et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Serum long noncoding RNA HOTAIR as a novel diagnostic and prognostic biomarker in glioblastoma multiforme
- (2018) Sze Kiat Tan et al. Molecular Cancer
- Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells
- (2018) Paolo Mellini et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Understanding and Treating Glioblastoma
- (2018) Wolfgang Wick et al. NEUROLOGIC CLINICS
- Six Years (2012–2018) of Researches on Catalytic EZH2 Inhibitors: The Boom of the 2‐Pyridone Compounds
- (2018) Rossella Fioravanti et al. CHEMICAL RECORD
- The anti-vascular endothelial growth factor receptor-1 monoclonal antibody D16F7 inhibits invasiveness of human glioblastoma and glioblastoma stem cells
- (2017) Maria Grazia Atzori et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells
- (2017) Evelina Miele et al. Oncotarget
- The EZH2 inhibitor GSK343 suppresses cancer stem-like phenotypes and reverses mesenchymal transition in glioma cells
- (2017) Tianfu Yu et al. Oncotarget
- The Histone Methyltransferase Ezh2 Controls Mechanisms of Adaptive Resistance to Tumor Immunotherapy
- (2017) Daniel Zingg et al. Cell Reports
- Indium-Catalyzed Formal N-Arylation and N-Alkylation of Pyrroles with Amines
- (2016) Kyohei Yonekura et al. ADVANCED SYNTHESIS & CATALYSIS
- Functional roles of enhancer of zeste homolog 2 in gliomas
- (2016) Yatao Yin et al. GENE
- Solvation thermodynamic mapping of molecular surfaces in AmberTools: GIST
- (2016) Steven Ramsey et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Design and development of pyrrole carbaldehyde: an effective pharmacophore for enoyl-ACP reductase
- (2016) Shrinivas D. Joshi et al. MEDICINAL CHEMISTRY RESEARCH
- Targeting EZH2 in cancer
- (2016) Kimberly H Kim et al. NATURE MEDICINE
- An update on the epigenetics of glioblastomas
- (2016) Wallax Augusto Silva Ferreira et al. Epigenomics
- Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance
- (2016) Alexei Brooun et al. Nature Communications
- Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells
- (2016) Natalie Grinshtein et al. Oncotarget
- EZH2 is a negative prognostic factor and exhibits pro-oncogenic activity in glioblastoma
- (2015) Junxia Zhang et al. CANCER LETTERS
- Involvement of pro-inflammatory cytokines and growth factors in the pathogenesis of Dupuytren's contracture: a novel target for a possible future therapeutic strategy?
- (2015) Enrica Bianchi et al. CLINICAL SCIENCE
- The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities
- (2015) Samuel Genheden et al. Expert Opinion on Drug Discovery
- ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB
- (2015) James A. Maier et al. Journal of Chemical Theory and Computation
- The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin
- (2015) Merry Gunawan et al. NATURE IMMUNOLOGY
- Differential expression of vascular endothelial growth factor A, its receptors VEGFR-1, -2, and -3 and co-receptors neuropilin-1 and -2 does not predict bevacizumab response in human astrocytomas
- (2015) Peter Baumgarten et al. NEURO-ONCOLOGY
- CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012
- (2015) Quinn T. Ostrom et al. NEURO-ONCOLOGY
- Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity
- (2015) Mona Meyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Polycomb-mediated loss of microRNA let-7c determines inflammatory macrophage polarization via PAK1-dependent NF-κB pathway
- (2014) W Zhang et al. CELL DEATH AND DIFFERENTIATION
- EZH2, a Potential Regulator of Dental Pulp Inflammation and Regeneration
- (2014) Tianqian Hui et al. JOURNAL OF ENDODONTICS
- Building Water Models: A Different Approach
- (2014) Saeed Izadi et al. Journal of Physical Chemistry Letters
- Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
- (2014) A. P. Patel et al. SCIENCE
- Gliomas and the vascular fragility of the blood brain barrier
- (2014) Luiz Gustavo Dubois et al. Frontiers in Cellular Neuroscience
- Epigenomic control of the innate immune response
- (2013) Joshua D Stender et al. CURRENT OPINION IN PHARMACOLOGY
- MMPBSA.py: An Efficient Program for End-State Free Energy Calculations
- (2012) Bill R. Miller et al. Journal of Chemical Theory and Computation
- Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation
- (2012) W. Qi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2
- (2012) Sharad K. Verma et al. ACS Medicinal Chemistry Letters
- Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF-
- (2011) J. Lohr et al. CLINICAL CANCER RESEARCH
- Open Babel: An open chemical toolbox
- (2011) Noel M O'Boyle et al. Journal of Cheminformatics
- EZH2 Is Essential for Glioblastoma Cancer Stem Cell Maintenance
- (2009) M.-L. Suva et al. CANCER RESEARCH
- Empirical Scoring Functions for Advanced Protein−Ligand Docking with PLANTS
- (2009) Oliver Korb et al. Journal of Chemical Information and Modeling
- VEGF receptor protein–tyrosine kinases: Structure and regulation
- (2008) Robert Roskoski BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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