标题
Chronic and Acute Toxicities of Aflatoxins: Mechanisms of Action
作者
关键词
-
出版物
International Journal of Environmental Research and Public Health
Volume 17, Issue 2, Pages 423
出版商
MDPI AG
发表日期
2020-01-09
DOI
10.3390/ijerph17020423
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Aflatoxin B1–Formamidopyrimidine DNA Adducts: Relationships between Structures, Free Energies, and Melting Temperatures
- (2019) Martin Klvana et al. MOLECULES
- Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins
- (2019) Rumani Singh et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Harmful Effects and Control Strategies of Aflatoxin B1 Produced by Aspergillus flavus and Aspergillus parasiticus Strains on Poultry: Review
- (2019) Ahmed Fouad et al. Toxins
- The multiple mechanisms that regulate p53 activity and cell fate
- (2019) Antonina Hafner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation
- (2019) Nina Germic et al. CELL DEATH AND DIFFERENTIATION
- Mechanisms underlying aflatoxin-associated mutagenesis – Implications in carcinogenesis
- (2019) Amanda K. McCullough et al. DNA REPAIR
- Selenium Deficiency Aggravates Aflatoxin B1–Induced Immunotoxicity in Chick Spleen by Regulating 6 Selenoprotein Genes and Redox/Inflammation/Apoptotic Signaling
- (2019) Ling Zhao et al. JOURNAL OF NUTRITION
- Characterization of rare NEIL1 variants found in East Asian populations
- (2019) Irina G. Minko et al. DNA REPAIR
- An unusually high production of hepatic aflatoxin B1-dihydrodiol, the possible explanation for the high susceptibility of ducks to aflatoxin B1
- (2019) Gonzalo J. Diaz et al. Scientific Reports
- Regulation of expression of drug-metabolizing enzymes by oncogenic signaling pathways in liver tumors: a review
- (2019) Albert Braeuning et al. Acta Pharmaceutica Sinica B
- Retrospective and Prospective Look at Aflatoxin Research and Development from a Practical Standpoint
- (2019) Noreddine Benkerroum International Journal of Environmental Research and Public Health
- Updates on the Effect of Mycotoxins on Male Reproductive Efficiency in Mammals
- (2019) Diala El. Khoury et al. Toxins
- Chronic neurodegeneration by aflatoxin B1 depends on alterations of brain enzyme activity and immunoexpression of astrocyte in male rats
- (2019) Ahmed Alsayyah et al. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
- Deciphering p53 signaling in tumor suppression
- (2018) Stephano S Mello et al. CURRENT OPINION IN CELL BIOLOGY
- Immunotoxicity of Aflatoxin M1 : as a potent suppressor of innate and acquired immune systems in a subacute study
- (2018) Kobra Shirani et al. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
- Aldehydes are the predominant forces inducing DNA damage and inhibiting DNA repair in tobacco smoke carcinogenesis
- (2018) Mao-wen Weng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genotoxicity of aflatoxins and their precursors in human cells
- (2018) M.G. Theumer et al. TOXICOLOGY LETTERS
- Histopathological Injuries, Ultrastructural Changes, and Depressed TLR Expression in the Small Intestine of Broiler Chickens with Aflatoxin B1
- (2018) Fengyuan Wang et al. Toxins
- Aflatoxin B1 and M1: Biological Properties and Their Involvement in Cancer Development
- (2018) Silvia Marchese et al. Toxins
- Aflatoxin-Guanine DNA Adducts and Oxidatively Induced DNA Damage in Aflatoxin-Treated Mice in Vivo as Measured by Liquid Chromatography-Tandem Mass Spectrometry with Isotope Dilution
- (2018) Erdem Coskun et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Aflatoxin G1 induced TNF-α-dependent lung inflammation to enhance DNA damage in alveolar epithelial cells
- (2018) Peilu Shao et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Aflatoxin B1 metabolism: Regulation by phase I and II metabolizing enzymes and chemoprotective agents
- (2018) Jiang Deng et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Combined Cytotoxicity of the Phycotoxin Okadaic Acid and Mycotoxins on Intestinal and Neuroblastoma Human Cell Models
- (2018) Aiko Hayashi et al. Toxins
- Roles of p21, p53, cyclin D1, CDK-4, estrogen receptor α in aflatoxin B1-induced cytotoxicity in testicular tissue of mice
- (2017) Toraj Zamir-Nasta et al. ENVIRONMENTAL TOXICOLOGY
- Effects of biological and mineral compounds in aflatoxin-contaminated diets on blood parameters and immune response of broiler chickens
- (2017) Mohsen Barati et al. JOURNAL OF APPLIED ANIMAL RESEARCH
- Prognostic and clinicopathological significance of cyclin B expression in patients with breast cancer
- (2017) Xi Sun et al. MEDICINE
- Forging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication Fork
- (2017) Katherine N. Choe et al. MOLECULAR CELL
- Mutational spectra of aflatoxin B1in vivo establish biomarkers of exposure for human hepatocellular carcinoma
- (2017) Supawadee Chawanthayatham et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NEIL1 protects against aflatoxin-induced hepatocellular carcinoma in mice
- (2017) Vladimir Vartanian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Environmentally relevant level of aflatoxin B 1 elicits toxic pro-inflammatory response in murine CNS-derived cells
- (2017) Jalil Mehrzad et al. TOXICOLOGY LETTERS
- Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity
- (2017) Purnima Bhat et al. Cell Death & Disease
- AFB1 hepatocarcinogenesis is via lipid peroxidation that inhibits DNA repair, sensitizes mutation susceptibility and induces aldehyde-DNA adducts at p53 mutational hotspot codon 249
- (2017) Mao-Wen Weng et al. Oncotarget
- Pathological Impairment, Cell Cycle Arrest and Apoptosis of Thymus and Bursa of Fabricius Induced by Aflatoxin-Contaminated Corn in Broilers
- (2017) Xi Peng et al. International Journal of Environmental Research and Public Health
- Impact of a Single Oral Acute Dose of Aflatoxin B1 on Liver Function/Cytokines and the Lymphoproliferative Response in C57Bl/6 Mice
- (2017) Angélica Ishikawa et al. Toxins
- Modulation of Intestinal Epithelial Permeability in Differentiated Caco-2 Cells Exposed to Aflatoxin M1 and Ochratoxin A Individually or Collectively
- (2017) Yanan Gao et al. Toxins
- Aflatoxin B1 Induces Reactive Oxygen Species-Mediated Autophagy and Extracellular Trap Formation in Macrophages
- (2017) Yanan An et al. Frontiers in Cellular and Infection Microbiology
- Multiple functions of p21 in cell cycle, apoptosis and transcriptional regulation after DNA damage
- (2016) Ansar Karimian et al. DNA REPAIR
- Identification of AFB1-interacting proteins and interactions between RPSA and AFB1
- (2016) Zhenhong Zhuang et al. JOURNAL OF HAZARDOUS MATERIALS
- Interactive effects of dietary protein concentration and aflatoxin B1on performance, nutrient digestibility, and gut health in broiler chicks
- (2016) X. Chen et al. POULTRY SCIENCE
- Mycotoxins modify the barrier function of Caco-2 cells through differential gene expression of specific claudin isoforms: Protective effect of illite mineral clay
- (2016) Alejandro Romero et al. TOXICOLOGY
- Immunosuppression following dietary aflatoxin B1 exposure: a review of the existing evidence
- (2016) Mahdieh Sadat Mohsenzadeh et al. Toxin Reviews
- Bax/Bak activation in the absence of Bid, Bim, Puma and p53
- (2016) J Zhang et al. Cell Death & Disease
- The molecular mechanism of G2/M cell cycle arrest induced by AFB1 in the jejunum
- (2016) Heng Yin et al. Oncotarget
- Effects of Aflatoxin B1 on T-Cell Subsets and mRNA Expression of Cytokines in the Intestine of Broilers
- (2015) Min Jiang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Prevention of Aflatoxin B1 Hepatoxicity by Dietary Selenium Is Associated with Inhibition of Cytochrome P450 Isozymes and Up-Regulation of 6 Selenoprotein Genes in Chick Liver
- (2015) Lv-Hui Sun et al. JOURNAL OF NUTRITION
- p53 in survival, death and metabolic health: a lifeguard with a licence to kill
- (2015) Flore Kruiswijk et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cigarette side-stream smoke lung and bladder carcinogenesis: inducing mutagenic acrolein-DNA adducts, inhibiting DNA repair and enhancing anchorage-independent-growth cell transformation
- (2015) Hyun-Wook Lee et al. Oncotarget
- Complete Protection against Aflatoxin B1-Induced Liver Cancer with a Triterpenoid: DNA Adduct Dosimetry, Molecular Signature, and Genotoxicity Threshold
- (2014) N. M. Johnson et al. Cancer Prevention Research
- Aflatoxin exposure during the first 1000 days of life in rural South Asia assessed by aflatoxin B1-lysine albumin biomarkers
- (2014) John D. Groopman et al. FOOD AND CHEMICAL TOXICOLOGY
- Environmentally Relevant Level of Aflatoxin B1 Dysregulates Human Dendritic Cells Through Signaling on Key Toll-Like Receptors
- (2014) Azam Mohammadi et al. INTERNATIONAL JOURNAL OF TOXICOLOGY
- Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
- (2014) Antonio Ayala et al. Oxidative Medicine and Cellular Longevity
- Growth, serum biochemistry, complement activity, and liver gene expression responses of Pekin ducklings to graded levels of cultured aflatoxin B1
- (2014) X. Chen et al. POULTRY SCIENCE
- Aflatoxin B1 interferes with the antigen-presenting capacity of porcine dendritic cells
- (2014) Jalil Mehrzad et al. TOXICOLOGY IN VITRO
- Mechanisms of Mycotoxin-induced Dermal Toxicity and Tumorigenesis Through Oxidative Stress-related Pathways
- (2014) Kunio Doi et al. Journal of Toxicologic Pathology
- Genetic Polymorphisms in DNA Repair Genes XRCC4 and XRCC5 and Aflatoxin B1–related Hepatocellular Carcinoma
- (2013) Xi-Dai Long et al. EPIDEMIOLOGY
- Biologically relevant doses of mixed aflatoxins B and G up-regulate MyD88, TLR2, TLR4 and CD14 transcripts in human PBMCs
- (2013) Amir Mohammad Malvandi et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Aflatoxin B1modulates the expression of phenotypic markers and cytokines by splenic lymphocytes of male F344 rats
- (2013) Guoqing Qian et al. JOURNAL OF APPLIED TOXICOLOGY
- In vitrostudy of AFB1and AFM1effects on human lymphoblastoid Jurkat T-cell model
- (2013) D. Luongo et al. Journal of Immunotoxicology
- Overview on aflatoxins and oxidative stress
- (2013) Daniela E. Marin et al. Toxin Reviews
- Protective Effects of Sodium Selenite against Aflatoxin B1-Induced Oxidative Stress and Apoptosis in Broiler Spleen
- (2013) Fengyuan Wang et al. International Journal of Environmental Research and Public Health
- Detection of Acrolein-Derived Cyclic DNA Adducts in Human Cells by Monoclonal Antibodies
- (2012) Jishen Pan et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Occurrence and distribution of aflatoxin contamination in groundnuts (Arachis hypogaea L) and population density of Aflatoxigenic Aspergilli in Malawi
- (2012) E.S. Monyo et al. CROP PROTECTION
- Effects of Aflatoxin on Liver and Protective Effectiveness of Esterified Glucomannan in Merino Rams
- (2012) Fatma Colakoglu et al. TheScientificWorldJOURNAL
- Modulation of macrophage activity by aflatoxins B1 and B2 and their metabolites aflatoxins M1 and M2
- (2012) G. Bianco et al. TOXICON
- 8-Hydroxydeoxyguanosine: Not mere biomarker for oxidative stress, but remedy for oxidative stress-implicated gastrointestinal diseases
- (2012) Chan-Young Ock WORLD JOURNAL OF GASTROENTEROLOGY
- Transport of Aflatoxin M1 in Human Intestinal Caco-2/TC7 Cells
- (2012) Francesca Caloni et al. Frontiers in Pharmacology
- Aflatoxins and growth impairment: A review
- (2011) Pornsri Khlangwiset et al. CRITICAL REVIEWS IN TOXICOLOGY
- Association between 8-oxo-7,8-dihydroguanine excretion and risk of lung cancer in a prospective study
- (2011) Steffen Loft et al. FREE RADICAL BIOLOGY AND MEDICINE
- Acrolein induced DNA damage, mutagenicity and effect on DNA repair
- (2011) Moon-shong Tang et al. MOLECULAR NUTRITION & FOOD RESEARCH
- A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers
- (2011) Siwanon Jirawatnotai et al. NATURE
- Cyclin D1 multitasks
- (2011) Jiri Bartek et al. NATURE
- In vitro effects of very low levels of aflatoxin B1 on free radicals production and bactericidal activity of bovine blood neutrophils
- (2011) J. Mehrzad et al. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
- Effect of glucomannan on haematological, coagulation and biochemical parameters in male rabbits fed aflatoxin-contaminated ration
- (2011) A. Eisa et al. World Mycotoxin Journal
- Aflatoxin levels, plasma vitamins A and E concentrations, and their association with HIV and hepatitis B virus infections in Ghanaians: a cross-sectional study
- (2011) Francis A Obuseh et al. Journal of the International AIDS Society
- Aflatoxin B1 in Affecting Broiler’s Performance, Immunity, and Gastrointestinal Tract: A Review of History and Contemporary Issues
- (2011) Agha W. Yunus et al. Toxins
- Maximal killing of lymphoma cells by DNA damage-inducing therapy requires not only the p53 targets Puma and Noxa, but also Bim
- (2010) L. Happo et al. BLOOD
- Secondary oxidation of cyclic 1,N2-propano and 1,N2-etheno-2′-deoxyguanosine DNA adducts. Consequences in oxidative stress biomarker development
- (2010) Stéphane Barbati et al. CHEMOSPHERE
- Global Burden of Aflatoxin-Induced Hepatocellular Carcinoma: A Risk Assessment
- (2010) Yan Liu et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Effects of chronic exposure of diets with reduced concentrations of aflatoxin and deoxynivalenol on growth and immune status of pigs1
- (2010) A. C. Chaytor et al. JOURNAL OF ANIMAL SCIENCE
- Association between birth outcomes and aflatoxin B1biomarker blood levels in pregnant women in Kumasi, Ghana
- (2010) Faisal M. B. Shuaib et al. TROPICAL MEDICINE & INTERNATIONAL HEALTH
- The aflatoxin-induced TP53 mutation at codon 249 (R249S): Biomarker of exposure, early detection and target for therapy
- (2009) Doriane Gouas et al. CANCER LETTERS
- PUMA, a potent killer with or without p53
- (2009) J Yu et al. ONCOGENE
- Oxidative Stress and Oxidative Damage in Carcinogenesis
- (2009) James E. Klaunig et al. TOXICOLOGIC PATHOLOGY
- The Polymorphism of XRCC3 Codon 241 and AFB1-Related Hepatocellular Carcinoma in Guangxi Population, China
- (2008) Xi Dai Long et al. ANNALS OF EPIDEMIOLOGY
- Aflatoxin-Related Immune Dysfunction in Health and in Human Immunodeficiency Virus Disease
- (2008) Yi Jiang et al. Clinical & Developmental Immunology
- The modulation of topoisomerase I-mediated DNA cleavage and the induction of DNA-topoisomerase I crosslinks by crotonaldehyde-derived DNA adducts
- (2008) T. S. Dexheimer et al. NUCLEIC ACIDS RESEARCH
- Effectiveness of melatonin on aflatoxicosis in chicks
- (2008) Hasan Özen et al. RESEARCH IN VETERINARY SCIENCE
- Immunotoxicity of aflatoxin B1: Impairment of the cell-mediated response to vaccine antigen and modulation of cytokine expression
- (2008) Guylaine M. Meissonnier et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now