DPP-4 Inhibitor Linagliptin is Neuroprotective in Hyperglycemic Mice with Stroke via the AKT/mTOR Pathway and Anti-apoptotic Effects
出版年份 2019 全文链接
标题
DPP-4 Inhibitor Linagliptin is Neuroprotective in Hyperglycemic Mice with Stroke via the AKT/mTOR Pathway and Anti-apoptotic Effects
作者
关键词
-
出版物
Neuroscience Bulletin
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-12-06
DOI
10.1007/s12264-019-00446-w
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association
- (2019) Emelia J. Benjamin et al. CIRCULATION
- Apoptotic cell death regulation in neurons
- (2019) Emilie Hollville et al. FEBS Journal
- The high need for trials assessing functional outcome after stroke rather than stroke prevention with GLP-1 agonists and DPP-4 inhibitors
- (2018) Vladimer Darsalia et al. Cardiovascular Diabetology
- Linagliptin and cardiovascular outcomes in type 2 diabetes after acute coronary syndrome or acute ischemic stroke
- (2018) Yan-Rong Li et al. Cardiovascular Diabetology
- The effect of DPP-4 inhibition to improve functional outcome after stroke is mediated by the SDF-1α/CXCR4 pathway
- (2018) Fausto Chiazza et al. Cardiovascular Diabetology
- Neuroprotective effects of the novel GLP-1 long acting analogue semaglutide in the MPTP Parkinson's disease mouse model
- (2018) Liping Zhang et al. NEUROPEPTIDES
- Glucagon-like receptor 1 agonists and DPP-4 inhibitors: Anti-diabetic drugs with anti-stroke potential
- (2018) Vladimer Darsalia et al. NEUROPHARMACOLOGY
- Novel dual GLP-1/GIP receptor agonists show neuroprotective effects in Alzheimer's and Parkinson's disease models
- (2018) Christian Hölscher NEUROPHARMACOLOGY
- Linagliptin treatment improves cerebrovascular function and remodeling and restores reduced cerebral perfusion in Type 2 diabetes
- (2016) Trevor Hardigan et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- The glucagon-like peptide 1 (GLP) receptor as a therapeutic target in Parkinson's disease: mechanisms of action
- (2016) Dilan Athauda et al. DRUG DISCOVERY TODAY
- An update on DPP-4 inhibitors in the management of type 2 diabetes
- (2016) Avivit Cahn et al. EXPERT OPINION ON EMERGING DRUGS
- The glucagon-like peptide-1 receptor agonist exendin-4 ameliorates warfarin-associated hemorrhagic transformation after cerebral ischemia
- (2016) Fangzhe Chen et al. Journal of Neuroinflammation
- Diabetes-mediated middle cerebral artery remodeling is restored by linagliptin: Interaction with the vascular smooth muscle cell endothelin system
- (2016) Abdul Yasir et al. LIFE SCIENCES
- Activation of GLP-1 Receptor Enhances Neuronal Base Excision Repair via PI3K-AKT-Induced Expression of Apurinic/Apyrimidinic Endonuclease 1
- (2016) Jenq-Lin Yang et al. Theranostics
- Cell Death Signaling
- (2015) Douglas R. Green et al. Cold Spring Harbor Perspectives in Biology
- Glucagon-Like Peptide-1 (GLP-1) Analog Liraglutide Inhibits Endothelial Cell Inflammation through a Calcium and AMPK Dependent Mechanism
- (2014) Nadia M. Krasner et al. PLoS One
- Alogliptin, a dipeptidylpeptidase-4 inhibitor, for patients with diabetes mellitus type 2, induces tolerance to focal cerebral ischemia in non-diabetic, normal mice
- (2013) Dong Yang et al. BRAIN RESEARCH
- The gut hormone glucagon-like peptide-1 produced in brain: is this physiologically relevant?
- (2013) Stefan Trapp et al. CURRENT OPINION IN PHARMACOLOGY
- Glucagon-Like Peptide 1 Reduces Endothelial Dysfunction, Inflammation, and Oxidative Stress Induced by Both Hyperglycemia and Hypoglycemia in Type 1 Diabetes
- (2013) A. Ceriello et al. DIABETES CARE
- Emerging DPP-4 inhibitors: focus on linagliptin for type 2 diabetes
- (2013) Baptist Gallwitz Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
- The DPP-4 Inhibitor Linagliptin Counteracts Stroke in the Normal and Diabetic Mouse Brain: A Comparison With Glimepiride
- (2012) V. Darsalia et al. DIABETES
- A novel stroke therapy of pharmacologically induced hypothermia after focal cerebral ischemia in mice
- (2012) Ko-Eun Choi et al. FASEB JOURNAL
- Neuroprotective actions of Glucagon-like peptide-1 in differentiated human neuroprogenitor cells
- (2012) Kalpana Velmurugan et al. JOURNAL OF NEUROCHEMISTRY
- Neuroprotective effect of the glucagon-like peptide-1 receptor agonist, synthetic exendin-4, in streptozotocin-induced diabetic rats
- (2011) Wei Jing Liu et al. BRITISH JOURNAL OF PHARMACOLOGY
- Anti-Inflammatory Properties of Exenatide in Human Pancreatic Islets
- (2011) S. R. Cechin et al. CELL TRANSPLANTATION
- Forecasting the Future of Cardiovascular Disease in the United States
- (2011) Paul A. Heidenreich et al. CIRCULATION
- Neuroprotective properties of GLP-1: theoretical and practical applications
- (2011) Jens Juul Holst et al. CURRENT MEDICAL RESEARCH AND OPINION
- Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes
- (2011) R. Kodera et al. DIABETOLOGIA
- A role for the gut-to-brain GLP-1-dependent axis in the control of metabolism
- (2009) Remy Burcelin et al. CURRENT OPINION IN PHARMACOLOGY
- Control of mitochondrial apoptosis by the Bcl-2 family
- (2009) J. K. Brunelle et al. JOURNAL OF CELL SCIENCE
- Reducing the risk of stroke in type 2 diabetes: pathophysiological and therapeutic perspectives
- (2009) Dirk Sander et al. JOURNAL OF NEUROLOGY
- Mutated recombinant human glucagon-like peptide-1 protects SH-SY5Y cells from apoptosis induced by amyloid-β peptide (1–42)
- (2008) Zhenxia Qin et al. NEUROSCIENCE LETTERS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started