MUC1-C regulates lineage plasticity driving progression to neuroendocrine prostate cancer
出版年份 2020 全文链接
标题
MUC1-C regulates lineage plasticity driving progression to neuroendocrine prostate cancer
作者
关键词
-
出版物
Nature Communications
Volume 11, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-01-17
DOI
10.1038/s41467-019-14219-6
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Next-generation characterization of the Cancer Cell Line Encyclopedia
- (2019) Mahmoud Ghandi et al. NATURE
- Genomic correlates of clinical outcome in advanced prostate cancer
- (2019) Wassim Abida et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TARGETING MUC1-C INHIBITS TWIST1 SIGNALING IN TRIPLE-NEGATIVE BREAST CANCER
- (2019) Tsuyoshi Hata et al. MOLECULAR CANCER THERAPEUTICS
- MUC1-C Activates The NuRD Complex To Drive Dedifferentiation of Triple-Negative Breast Cancer Cells
- (2019) Tsuyoshi Hata et al. CANCER RESEARCH
- N-Myc–mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer
- (2019) Adeline Berger et al. JOURNAL OF CLINICAL INVESTIGATION
- MUC1-C represses the RASSF1A tumor suppressor in human carcinoma cells
- (2019) Hasan Rajabi et al. ONCOGENE
- Clinical and molecular features of treatment-related neuroendocrine prostate cancer
- (2018) Shusuke Akamatsu et al. INTERNATIONAL JOURNAL OF UROLOGY
- Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study
- (2018) Rahul Aggarwal et al. JOURNAL OF CLINICAL ONCOLOGY
- Cellular plasticity and the neuroendocrine phenotype in prostate cancer
- (2018) Alastair H. Davies et al. Nature Reviews Urology
- MUC1-C activates polycomb repressive complexes and downregulates tumor suppressor genes in human cancer cells
- (2018) Hasan Rajabi et al. ONCOGENE
- Inhibition of MUC1-C entering nuclear suppresses MYC expression and attenuates malignant growth in esophageal squamous cell carcinoma
- (2018) Zhongwei Xin et al. OncoTargets and Therapy
- Neuroendocrine Differentiation in Prostate Cancer: Emerging Biology, Models, and Therapies
- (2018) Loredana Puca et al. Cold Spring Harbor Perspectives in Medicine
- Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance
- (2018) Piyush B. Gupta et al. Cell Stem Cell
- Inhibition of MUC1-C regulates metabolism by AKT pathway in esophageal squamous cell carcinoma
- (2018) Xin GongSun et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Biology and evolution of poorly differentiated neuroendocrine tumors
- (2017) David S Rickman et al. NATURE MEDICINE
- SOX2 promotes lineage plasticity and antiandrogen resistance in TP53 - and RB1 -deficient prostate cancer
- (2017) Ping Mu et al. SCIENCE
- Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance
- (2017) Sheng Yu Ku et al. SCIENCE
- Overexpression of MUC1 and Genomic Alterations in Its Network Associate with Prostate Cancer Progression
- (2017) Xiaozeng Lin et al. NEOPLASIA
- MUC1-C activates EZH2 expression and function in human cancer cells
- (2017) Hasan Rajabi et al. Scientific Reports
- N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer
- (2016) Etienne Dardenne et al. CANCER CELL
- N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells
- (2016) John K. Lee et al. CANCER CELL
- Inhibition of MUC1-C Suppresses MYC Expression and Attenuates Malignant Growth in KRAS Mutant Lung Adenocarcinomas
- (2016) Audrey Bouillez et al. CANCER RESEARCH
- Numb and Numbl act to determine mammary myoepithelial cell fate, maintain epithelial identity, and support lactogenesis
- (2016) Yue Zhang et al. FASEB JOURNAL
- MUC1-C Represses the Crumbs Complex Polarity Factor CRB3 and Downregulates the Hippo Pathway
- (2016) Maroof Alam et al. MOLECULAR CANCER RESEARCH
- Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer
- (2016) Himisha Beltran et al. NATURE MEDICINE
- A decade of transcription factor-mediated reprogramming to pluripotency
- (2016) Kazutoshi Takahashi et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- MUC1-C activates BMI1 in human cancer cells
- (2016) M Hiraki et al. ONCOGENE
- MUC1 is upregulated in advanced prostate cancer and is an independent prognostic factor
- (2016) V Genitsch et al. PROSTATE CANCER AND PROSTATIC DISEASES
- The Master Neural Transcription Factor BRN2 Is an Androgen Receptor–Suppressed Driver of Neuroendocrine Differentiation in Prostate Cancer
- (2016) Jennifer L. Bishop et al. Cancer Discovery
- MUC1 Expression by Immunohistochemistry Is Associated with Adverse Pathologic Features in Prostate Cancer: A Multi-Institutional Study
- (2016) Okyaz Eminaga et al. PLoS One
- Integrative Clinical Genomics of Advanced Prostate Cancer
- (2015) Dan Robinson et al. CELL
- The Molecular Taxonomy of Primary Prostate Cancer
- (2015) Adam Abeshouse et al. CELL
- Inhibition of Pluripotency Networks by the Rb Tumor Suppressor Restricts Reprogramming and Tumorigenesis
- (2015) Michael S. Kareta et al. Cell Stem Cell
- Intracellular Targeting of the Oncogenic MUC1-C Protein with a Novel GO-203 Nanoparticle Formulation
- (2015) M. Hasegawa et al. CLINICAL CANCER RESEARCH
- MUC1-C activates the TAK1 inflammatory pathway in colon cancer
- (2015) H Takahashi et al. ONCOGENE
- The Placental Gene PEG10 Promotes Progression of Neuroendocrine Prostate Cancer
- (2015) Shusuke Akamatsu et al. Cell Reports
- Polycomb-mediated silencing in neuroendocrine prostate cancer
- (2015) Pier-Luc Clermont et al. Clinical Epigenetics
- Characterization of the MUC1-C Cytoplasmic Domain as a Cancer Target
- (2015) Deepak Raina et al. PLoS One
- Proposed Morphologic Classification of Prostate Cancer With Neuroendocrine Differentiation
- (2014) Jonathan I. Epstein et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Targeting the Oncogenic MUC1-C Protein Inhibits Mutant EGFR-Mediated Signaling and Survival in Non-Small Cell Lung Cancer Cells
- (2014) A. Kharbanda et al. CLINICAL CANCER RESEARCH
- Mammary Morphogenesis and Regeneration Require the Inhibition of EMT at Terminal End Buds by Ovol2 Transcriptional Repressor
- (2014) Kazuhide Watanabe et al. DEVELOPMENTAL CELL
- Epithelial-to-mesenchymal transition and estrogen receptor α mediated epithelial dedifferentiation mark the development of benign prostatic hyperplasia
- (2014) Rui Shao et al. PROSTATE
- POU-III Transcription Factors (Brn1, Brn2, and Oct6) Influence Neurogenesis, Molecular Identity, and Migratory Destination of Upper-Layer Cells of the Cerebral Cortex
- (2012) Martin H. Dominguez et al. CEREBRAL CORTEX
- MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches
- (2012) D W Kufe ONCOGENE
- MUC1c Regulates Cell Survival in Pancreatic Cancer by Preventing Lysosomal Permeabilization
- (2012) Sulagna Banerjee et al. PLoS One
- MUC1-C oncoprotein confers androgen-independent growth of human prostate cancer cells
- (2012) Hasan Rajabi et al. PROSTATE
- Dependence on the MUC1-C Oncoprotein in Non-Small Cell Lung Cancer Cells
- (2011) D. Raina et al. MOLECULAR CANCER THERAPEUTICS
- Molecular Characterization of Neuroendocrine Prostate Cancer and Identification of New Drug Targets
- (2011) H. Beltran et al. Cancer Discovery
- Small Cell Carcinoma of the Prostate
- (2009) Wenle Wang et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Direct Targeting of the Mucin 1 Oncoprotein Blocks Survival and Tumorigenicity of Human Breast Carcinoma Cells
- (2009) D. Raina et al. CANCER RESEARCH
- MUC1 oncoprotein is a druggable target in human prostate cancer cells
- (2009) M. D. Joshi et al. MOLECULAR CANCER THERAPEUTICS
- A role for epithelial-mesenchymal transition in the etiology of benign prostatic hyperplasia
- (2009) Paloma Alonso-Magdalena et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation