Polycomb-mediated silencing in neuroendocrine prostate cancer

Genotranscriptomic meta-analysis of the Polycomb gene CBX2 in human cancers: initial evidence of an oncogenic role

(2014) P-L Clermont et al.   BRITISH JOURNAL OF CANCER

Aggressive Variants of Castration-Resistant Prostate Cancer

(2014) H. Beltran et al.   CLINICAL CANCER RESEARCH

Chromodomain Antagonists That Target the Polycomb-Group Methyllysine Reader Protein Chromobox Homolog 7 (CBX7)

(2014) Chakravarthi Simhadri et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Many Faces of Neuroendocrine Differentiation in Prostate Cancer Progression

(2014) Stéphane Terry et al.   Frontiers in Oncology

Synthetic trimethyllysine receptors that bind histone 3, trimethyllysine 27 (H3K27me3) and disrupt its interaction with the epigenetic reader protein CBX7

(2013) Sara Tabet et al.   BIOORGANIC & MEDICINAL CHEMISTRY

High Fidelity Patient-Derived Xenografts for Accelerating Prostate Cancer Discovery and Drug Development

(2013) D. Lin et al.   CANCER RESEARCH

Rb Loss Is Characteristic of Prostatic Small Cell Neuroendocrine Carcinoma

(2013) H.-L. Tan et al.   CLINICAL CANCER RESEARCH

Altered DNA Methylation Landscapes of Polycomb-Repressed Loci Are Associated with Prostate Cancer Progression and ERG Oncogene Expression in Prostate Cancer

(2013) K. Kron et al.   CLINICAL CANCER RESEARCH

CHD5 Is Required for Neurogenesis and Has a Dual Role in Facilitating Gene Expression and Polycomb Gene Repression

(2013) Chris M. Egan et al.   DEVELOPMENTAL CELL

Occupying Chromatin: Polycomb Mechanisms for Getting to Genomic Targets, Stopping Transcriptional Traffic, and Staying Put

(2013) Jeffrey A. Simon et al.   MOLECULAR CELL

TET enzymes, TDG and the dynamics of DNA demethylation

(2013) Rahul M. Kohli et al.   NATURE

Charting a dynamic DNA methylation landscape of the human genome

(2013) Michael J. Ziller et al.   NATURE

A new world of Polycombs: unexpected partnerships and emerging functions

(2013) Yuri B. Schwartz et al.   NATURE REVIEWS GENETICS

Epigenetic programming and reprogramming during development

(2013) Irene Cantone et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Transcriptional regulation by Polycomb group proteins

(2013) Luciano Di Croce et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Proteomic characterization of novel histone post-translational modifications

(2013) Anna M Arnaudo et al.   Epigenetics & Chromatin

Cancer Epigenetics: From Mechanism to Therapy

(2012) Mark A. Dawson et al.   CELL

Metabolic Regulation of Epigenetics

(2012) Chao Lu et al.   Cell Metabolism

The bromodomain interaction module

(2012) Panagis Filippakopoulos et al.   FEBS LETTERS

Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship

(2012) Julian R. Molina et al.   MAYO CLINIC PROCEEDINGS

PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes

(2012) Zhonghua Gao et al.   MOLECULAR CELL

Trials with ‘epigenetic’ drugs: An update

(2012) Angela Nebbioso et al.   Molecular Oncology

The time of timing: How Polycomb proteins regulate neurogenesis

(2011) Giuseppe Testa   BIOESSAYS

Cell of Origin of Small Cell Lung Cancer: Inactivation of Trp53 and Rb1 in Distinct Cell Types of Adult Mouse Lung

(2011) Kate D. Sutherland et al.   CANCER CELL

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

ERG gene rearrangements are common in prostatic small cell carcinomas

(2011) Tamara L Lotan et al.   MODERN PATHOLOGY

Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer

(2011) Francesco Crea et al.   Molecular Cancer

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

Roles of the Polycomb group proteins in stem cells and cancer

(2011) H Richly et al.   Cell Death & Disease

Molecular Characterization of Neuroendocrine Prostate Cancer and Identification of New Drug Targets

(2011) H. Beltran et al.   Cancer Discovery

Recognition and Specificity Determinants of the Human Cbx Chromodomains

(2010) Lilia Kaustov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective inhibition of BET bromodomains

(2010) Panagis Filippakopoulos et al.   NATURE

Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex

(2010) J. D. Pereira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel motifs distinguish multiple homologues of Polycomb in vertebrates: expansion and diversification of the epigenetic toolkit

(2009) Ramamoorthy Senthilkumar et al.   BMC GENOMICS

An operational definition of epigenetics

(2009) S. L. Berger et al.   GENES & DEVELOPMENT

ASAP1, a Gene at 8q24, Is Associated with Prostate Cancer Metastasis

(2008) D. Lin et al.   CANCER RESEARCH

Epigenetics in Cancer

(2008) Manel Esteller   NEW ENGLAND JOURNAL OF MEDICINE