Chlorzoxazone, a small molecule drug, augments immunosuppressive capacity of mesenchymal stem cells via modulation of FOXO3 phosphorylation

FOXO3, a Molecular Search for the Fountain of Youth

(2019) Willem E. Fibbe et al.   Cell Stem Cell

Small Molecules to Improve ER Proteostasis in Disease

(2019) Vicente Gonzalez-Teuber et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Fine-tuning of FOXO3A in cHL as a survival mechanism and a hallmark of abortive plasma cell differentiation

(2018) Clarissa D. Osswald et al.   BLOOD

Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities

(2018) Jacques Galipeau et al.   Cell Stem Cell

Acute Kidney Injury as a Condition of Renal Senescence

(2018) Lucia Andrade et al.   CELL TRANSPLANTATION

miR-450b Promotes Osteogenic Differentiation In Vitro and Enhances Bone Formation In Vivo by Targeting BMP3

(2018) Linyuan Fan et al.   STEM CELLS AND DEVELOPMENT

Regulatory T cells in the treatment of disease

(2018) Amir Sharabi et al.   NATURE REVIEWS DRUG DISCOVERY

Benefit of cardiopoietic mesenchymal stem cell therapy on left ventricular remodelling: results from the Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-1) study

(2017) John R. Teerlink et al.   EUROPEAN JOURNAL OF HEART FAILURE

Geminin facilitates FoxO3 deacetylation to promote breast cancer cell metastasis

(2017) Lei Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis

(2017) Xuekun Li et al.   Nature Communications

Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function

(2017) Luca Perico et al.   Nature Communications

Identification and characterization of two functional variants in the human longevity gene FOXO3

(2017) Friederike Flachsbart et al.   Nature Communications

Activation of autophagy by FOXO3 regulates redox homeostasis during osteogenic differentiation

(2016) M. C. Gómez-Puerto et al.   Autophagy

Comparative study of different approaches for preparation of chlorzoxazone orodispersible tablets

(2016) Helal Abdo Moqbel et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Foxo3 Transcription Factor Drives Pathogenic T Helper 1 Differentiation by Inducing the Expression of Eomes

(2016) Caroline Stienne et al.   IMMUNITY

Rebuilding the Damaged Heart: Mesenchymal Stem Cells, Cell-Based Therapy, and Engineered Heart Tissue

(2016) Samuel Golpanian et al.   PHYSIOLOGICAL REVIEWS

PI3kα and STAT1 Interplay Regulates Human Mesenchymal Stem Cell Immune Polarization

(2015) Marwan Mounayar et al.   STEM CELLS

Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophy

(2015) Giulia Milan et al.   Nature Communications

Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications

(2014) Ying Wang et al.   NATURE IMMUNOLOGY

Immunological characterization of multipotent mesenchymal stromal cells—The International Society for Cellular Therapy (ISCT) working proposal

(2013) Mauro Krampera et al.   CYTOTHERAPY

FoxO3 coordinates metabolic pathways to maintain redox balance in neural stem cells

(2013) Hyeonju Yeo et al.   EMBO JOURNAL

FOXO3A directs a protective autophagy program in haematopoietic stem cells

(2013) Matthew R. Warr et al.   NATURE

Mesenchymal stem cells: a double-edged sword in regulating immune responses

(2012) W Li et al.   CELL DEATH AND DIFFERENTIATION

Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling

(2012) Astrid De Boeck et al.   GUT

Human umbilical cord mesenchymal stem cells improve liver function and ascites in decompensated liver cirrhosis patients

(2012) Zheng Zhang et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Indoleamine 2,3 dioxygenase and metabolic control of immune responses

(2012) David H. Munn et al.   TRENDS IN IMMUNOLOGY

Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth

(2011) Michael Quante et al.   CANCER CELL

Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus

(2010) Lingyun Sun et al.   ARTHRITIS AND RHEUMATISM

Stem cells in the treatment of inflammatory arthritis

(2010) Alan Tyndall et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

I B kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia

(2010) N. Chapuis et al.   BLOOD

A New Mesenchymal Stem Cell (MSC) Paradigm: Polarization into a Pro-Inflammatory MSC1 or an Immunosuppressive MSC2 Phenotype

(2010) Ruth S. Waterman et al.   PLoS One

The NKG2D ligand ULBP4 binds to TCR 9/ 2 and induces cytotoxicity to tumor cells through both TCR   and NKG2D

(2009) Y. Kong et al.   BLOOD

Flk-1+mesenchymal stem cells aggravate collagen-induced arthritis by up-regulating interleukin-6

(2009) B. Chen et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression

(2009) Erika L. Spaeth et al.   PLoS One

Mesenchymal stem cells induce mature dendritic cells into a novel Jagged-2-dependent regulatory dendritic cell population

(2008) B. Zhang et al.   BLOOD

How Do Mesenchymal Stromal Cells Suppress T Cells?

(2008) Armand Keating   Cell Stem Cell

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

(2008) Katarina Le Blanc et al.   LANCET