Sestrin2 protects dendritic cells against endoplasmic reticulum stress-related apoptosis induced by high mobility group box-1 protein

The Unfolded Protein Response and Cell Fate Control

(2018) Claudio Hetz et al.   MOLECULAR CELL

High-mobility group box 1 protein (HMGB1) operates as an alarmin outside as well as inside cells

(2018) Ulf Andersson et al.   SEMINARS IN IMMUNOLOGY

Contribution of Dendritic Cell Responses to Sepsis-Induced Immunosuppression and to Susceptibility to Secondary Pneumonia

(2018) Marwan Bouras et al.   Frontiers in Immunology

Carbon monoxide protects against hepatic steatosis in mice by inducing sestrin-2 via the PERK-eIF2α-ATF4 pathway

(2017) Hyo Jeong Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Transcription Factor C/EBP Homologous Protein in Health and Diseases

(2017) Yuan Yang et al.   Frontiers in Immunology

Sepsis-Induced Endoplasmic Reticulum Stress

(2016) Elliott D. Crouser   CRITICAL CARE MEDICINE

The Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress

(2016) W. Rozpedek et al.   CURRENT MOLECULAR MEDICINE

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Cell-autonomous stress responses in innate immunity

(2016) Julien Moretti et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Protein misfolding in the endoplasmic reticulum as a conduit to human disease

(2016) Miao Wang et al.   NATURE

Endoplasmic reticulum stress-mediated induction of SESTRIN 2 potentiates cell survival

(2016) Svetlana Saveljeva et al.   Oncotarget

Sestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from non-canonical necroptotic cell death

(2016) Boxiao Ding et al.   Scientific Reports

Endoplasmic Reticulum Stress in Immunity

(2015) Sarah E. Bettigole et al.   Annual Review of Immunology

Role of sestrin2 in the regulation of proinflammatory signaling in macrophages

(2015) Ji Hye Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protein kinase R-like ER kinase and its role in endoplasmic reticulum stress-decided cell fate

(2015) Z Liu et al.   Cell Death & Disease

Regulation of Dendritic Cell Function in Inflammation

(2015) André Said et al.   Journal of Immunology Research

Enhanced Dendritic Cell Survival Attenuates Lipopolysaccharide-Induced Immunosuppression and Increases Resistance to Lethal Endotoxic Shock

(2014) E. L. Gautier et al.   JOURNAL OF IMMUNOLOGY

TLR4-dependent activation of dendritic cells by an HMGB1-derived peptide adjuvant

(2014) Rebecca Saenz et al.   Journal of Translational Medicine

HMGB1 in health and disease

(2014) Rui Kang et al.   MOLECULAR ASPECTS OF MEDICINE

Hepatoprotective role of Sestrin2 against chronic ER stress

(2014) Hwan-Woo Park et al.   Nature Communications

Nelfinavir and bortezomib inhibit mTOR activity via ATF4-mediated sestrin-2 regulation

(2013) Ansgar Brüning et al.   Molecular Oncology

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

(2013) Jaeseok Han et al.   NATURE CELL BIOLOGY

Sestrin2 integrates Akt and mTOR signaling to protect cells against energetic stress-induced death

(2012) I Ben-Sahra et al.   CELL DEATH AND DIFFERENTIATION

Maintenance of Metabolic Homeostasis by Sestrin2 and Sestrin3

(2012) Jun Hee Lee et al.   Cell Metabolism

Endoplasmic reticulum stress and its regulator XBP-1 contributes to dendritic cell maturation and activation induced by high mobility group box-1 protein

(2012) Xiao-mei Zhu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure

(2011) Jonathan S. Boomer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Stressin' Sestrins take an aging fight

(2010) Andrei V. Budanov et al.   EMBO Molecular Medicine

Dendritic Cell Apoptosis: Regulation of Tolerance versus Immunity

(2010) R. Kushwah et al.   JOURNAL OF IMMUNOLOGY

Endotoxin causes functional endoplasmic reticulum failure, possibly mediated by mitochondria

(2009) Andrey V. Kozlov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Effect of High Mobility Group Box-1 Protein on Splenic Dendritic Cell Maturation in Rats

(2009) Xiao-mei Zhu et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

p53 Strikes mTORC1 by Employing Sestrins

(2008) Nissim Hay   Cell Metabolism

The Endoplasmic Reticulum Stress-Mediated Apoptosis Signal Pathway Is Involved in Sepsis-Induced Abnormal Lymphocyte Apoptosis

(2008) T. Ma et al.   EUROPEAN SURGICAL RESEARCH