Drp1-mediated mitochondrial fission promotes renal fibroblast activation and fibrogenesis

Drp1S600 phosphorylation regulates mitochondrial fission and progression of nephropathy in diabetic mice

(2019) Daniel L. Galvan et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanisms of Renal Fibrosis

(2018) Benjamin D. Humphreys   Annual Review of Physiology

Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension

(2018) Kuang-Hueih Chen et al.   CIRCULATION

Organelles: The Emerging Signalling Chart of Mitochondrial Dynamics

(2018) Tito Calì et al.   CURRENT BIOLOGY

Interleukin-1βActivates a MYC-Dependent Metabolic Switch in Kidney Stromal Cells Necessary for Progressive Tubulointerstitial Fibrosis

(2018) Dario R. Lemos et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors

(2018) Grace R. Anderson et al.   Nature Communications

Long noncoding RNA lnc-TSI inhibits renal fibrogenesis by negatively regulating the TGF-β/Smad3 pathway

(2018) Peng Wang et al.   Science Translational Medicine

Drp1-Dependent Mitochondrial Fission Plays Critical Roles in Physiological and Pathological Progresses in Mammals

(2017) Chenxia Hu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The constriction and scission machineries involved in mitochondrial fission

(2017) Felix Kraus et al.   JOURNAL OF CELL SCIENCE

Dynamin-Related Protein 1 Deficiency Promotes Recovery from AKI

(2017) Heather M. Perry et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Altered Mitochondrial Signalling and Metabolism in Cancer

(2017) Esita Chattopadhyay et al.   Frontiers in Oncology

Heat Shock Protein 72 Antagonizes STAT3 Signaling to Inhibit Fibroblast Accumulation in Renal Fibrogenesis

(2016) Yi Zhou et al.   AMERICAN JOURNAL OF PATHOLOGY

Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function

(2016) Lena Pernas et al.   Annual Review of Physiology

Atg5-mediated autophagy deficiency in proximal tubules promotes cell cycle G2/M arrest and renal fibrosis

(2016) Huiyan Li et al.   Autophagy

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming

(2016) Michael D. Buck et al.   CELL

The origin of renal fibroblasts/myofibroblasts and the signals that trigger fibrosis

(2016) Yu Bo Yang Sun et al.   DIFFERENTIATION

Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling

(2016) Hidenori Otera et al.   JOURNAL OF CELL BIOLOGY

Dynamin-Related Protein 1 Deficiency Improves Mitochondrial Fitness and Protects against Progression of Diabetic Nephropathy

(2016) B. A. Ayanga et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mitochondrial Dynamics and Metabolic Regulation

(2016) Timothy Wai et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Glycolytic Reprogramming in Myofibroblast Differentiation and Lung Fibrosis

(2015) Na Xie et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Novel curcumin analog C66 prevents diabetic nephropathy via JNK pathway with the involvement of p300/CBP-mediated histone acetylation

(2015) Yangwei Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Deregulated Myc Requires MondoA/Mlx for Metabolic Reprogramming and Tumorigenesis

(2015) Patrick A. Carroll et al.   CANCER CELL

Glycolysis-Mediated Changes in Acetyl-CoA and Histone Acetylation Control the Early Differentiation of Embryonic Stem Cells

(2015) Arieh Moussaieff et al.   Cell Metabolism

Mitochondrial Division Is Requisite to RAS-Induced Transformation and Targeted by Oncogenic MAPK Pathway Inhibitors

(2015) Madhavika N. Serasinghe et al.   MOLECULAR CELL

Erk2 Phosphorylation of Drp1 Promotes Mitochondrial Fission and MAPK-Driven Tumor Growth

(2015) Jennifer A. Kashatus et al.   MOLECULAR CELL

Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development

(2014) Hyun Mi Kang et al.   NATURE MEDICINE

PKM2 Regulates Chromosome Segregation and Mitosis Progression of Tumor Cells

(2013) Yuhui Jiang et al.   MOLECULAR CELL

Origin and function of myofibroblasts in kidney fibrosis

(2013) Valerie S LeBleu et al.   NATURE MEDICINE

Mitochondrial Dynamics — Mitochondrial Fission and Fusion in Human Diseases

(2013) Stephen L. Archer   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial Fission Triggered by Hyperglycemia Is Mediated by ROCK1 Activation in Podocytes and Endothelial Cells

(2012) Wenjian Wang et al.   Cell Metabolism

Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer

(2012) Jalees Rehman et al.   FASEB JOURNAL

Myofibroblasts in interstitial lung diseases show diverse electron microscopic and invasive features

(2012) Henna M Karvonen et al.   LABORATORY INVESTIGATION

Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health

(2011) David C. Chan   Annual Review of Genetics

Cellular and molecular mechanisms of renal fibrosis

(2011) Youhua Liu   Nature Reviews Nephrology

A unique chromatin signature uncovers early developmental enhancers in humans

(2010) Alvaro Rada-Iglesias et al.   NATURE

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models

(2009) Craig Brooks et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial function and morphology are impaired inparkin-mutant fibroblasts

(2008) Heather Mortiboys et al.   ANNALS OF NEUROLOGY