Review
Immunology
Le Xiong, Stephen L. L. Nutt, Cyril Seillet
Summary: Innate lymphoid cells (ILCs) serve as a link between sensory cells and effector cells, contributing to tissue homeostasis and adaptation to changing environmental conditions. Studying the non-canonical functions of these cells provides insights into their regulation and adaptability.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Monika Kuczynska, Patrycja Jakubek, Agnieszka Bartoszek
Summary: The concept of oxidative stress and the search for antioxidant-based remedies has gained immense interest. However, commercial success of antioxidants has surpassed research on the exact redox mechanisms that control health and disease states. This review explores the redox network formed by ROS and cellular molecules, and its regulation of genomic and proteomic processes. It also highlights the concept of reductive stress, which is less well-established compared to oxidative stress.
Article
Biochemistry & Molecular Biology
Albert Lu
Summary: NPC1 plays a central role in cholesterol egress from endolysosomes, but alternative pathways may exist. Understanding these mechanisms could have important implications for lysosomal storage disorder therapies.
Editorial Material
Biochemistry & Molecular Biology
Richard Huskey
Summary: Gossip is more than just trash talk, it can influence behavior, foster cooperation, and increase group affiliation.
Editorial Material
Biochemistry & Molecular Biology
Peter Macheroux
Summary: In light of the rapid climate change, plants are facing challenges that may impact crop production and global food security. Therefore, understanding plant defense and adaptation mechanisms in hostile environments is crucial.
Review
Biotechnology & Applied Microbiology
Yi Yang, Zhenhai Fu, Wei Zhu, Huizhu Hu, Jian'an Wang
Summary: Recent advances in optical tweezer technology have shown promising potential for applications in cardiovascular medicine. This article summarizes the findings of studies conducted using optical tweezers, which include nanomechanical measurements and manipulation of various biological components. The implications of these findings in disease diagnosis and treatment are discussed, along with potential future applications.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Review
Plant Sciences
Suresh Kumar, Santosh Kumar, Trilochan Mohapatra
Summary: Nutrients such as nitrogen (N), phosphorus (P), sulfur (S), zinc (Zn), and iron (Fe) are essential for the optimal growth, development, and productivity of plants. Plant responses to deficiencies of these nutrients are mainly studied separately, but there is limited research on the molecular basis of interactions among them. Recent advances have identified master regulators like phosphate starvation response 1 (PHR1) and light-responsive transcription factors involved in coordinating nutrient responses in plants. Understanding the interactions between macro- and micro-nutrients could help breeders improve nutrient use efficiency and crop yield/quality, especially in the face of changing climatic conditions.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Elis Cristina Araujo Eleutherio, Rayne Stfhany Silva Magalhaes, Aline de Araujo Brasil, Jose Raphael Monteiro Neto, Luan de Holanda Paranhos
Summary: During cellular respiration, radicals like superoxide can cause cell damage, but cells use the enzyme Cu/Zn Superoxide Dismutase (SOD1) to convert superoxide into oxygen and hydrogen peroxide. In addition to its primary function, SOD1 also plays other roles, such as activating gene transcription or functioning as an RNA binding protein.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
(2021)
Article
Biochemistry & Molecular Biology
Guillermo H. Jimenez Aleman, Venkatesh P. Thirumalaikumar, Georg Jander, Alisdair R. Fernie, Aleksandra Skirycz
Summary: The oxylipin 12-oxo-phytodienoic acid (OPDA) is a biosynthetic precursor of the plant hormone jasmonic acid, but also functions as a signaling molecule independent of jasmonates. OPDA is involved in various biological processes across plant species, including defense and stress responses, growth regulation, and development. This article summarizes what is known about OPDA metabolism and signaling, discussing its jasmonate dependent and independent roles, as well as open questions regarding the OPDA protein interactome and biological roles of OPDA conjugates.
Article
Plant Sciences
Miren Arzac, Beatriz Fernandez-Marin, Jose Garcia-Plazaola
Summary: Plastoglobules are lipoprotein structures attached to thylakoid membranes in chloroplasts. They are ubiquitous under non-stress conditions and their morphology changes depending on the specific stress. The study quantified the morphological attributes of plastoglobules from over 1000 TEM images published over the last 53 years, showing that plastoglobules are spherical with an average diameter of 100-200 nm under non-stress conditions. The analysis also revealed a trade-off between increasing the number or diameter of plastoglobules in response to different stresses.
Review
Biotechnology & Applied Microbiology
Matthias W. Laschke, Thomas Spaeter, Michael D. Menger
Summary: Adipose tissue-derived microvascular fragments have the ability to rapidly reassemble into microvascular networks, exhibit angiogenic activity, and serve as a source of endothelial progenitor cells and multipotent mesenchymal stromal cells. They also play a crucial role in tissue integration of implanted biomaterials.
TRENDS IN BIOTECHNOLOGY
(2021)
Review
Microbiology
J. Knisz, R. Eckert, L. M. Gieg, A. Koerdt, J. S. Lee, E. R. Silva, T. L. Skovhus, B. A. An Stepec, S. A. Wade
Summary: Microbiologically influenced corrosion (MIC) is a growing concern affecting various materials and sectors. Despite the global efforts to address MIC, there is limited interdisciplinary collaboration and information sharing. This review emphasizes the importance of non-biological aspects in understanding MIC and proposes approaches to tackle MIC-related challenges. It also highlights the need for microbiologists' expertise in advancing this field. Overall, this review aims to bridge the siloed nature of MIC research and encourage microbiologists to contribute to this important topic.
FEMS MICROBIOLOGY REVIEWS
(2023)
Editorial Material
Hematology
Bethany T. Samuelson Bannow
Summary: In the largest meta-analysis to date on the topic, Valeriani et al identified 4 clear benefits of using anticoagulation to treat splanchnic vein thrombosis (SVT), including increased recanalization, decreased thrombosis progression, decreased major bleeding, and decreased mortality.
Article
Environmental Sciences
Zhimin Xu, Yuxue Zhang, Liping Lin, Lei Wang, Weimin Sun, Chunguang Liu, Guohui Yu, Jieping Yu, Yao Lv, Jieting Chen, Xueqing Chen, Lingfang Fu, Yifan Wang
Summary: Differentially charged microplastics (MPs) generated from plastic aging can be found widely in the agricultural ecosystem. However, little is known about the toxic effects of MPs on plants and their absorption and accumulation characteristics. This study investigated the effects of MPs exposure on leaf lettuce through five different experiments, simulating root absorption in hydroponics. The results showed that MPs exposure caused growth inhibition, root lignification, root cell apoptosis, oxidative stress responses, chlorophyll decomposition, and hindered electron transfer within the PSII photosystem. Additionally, MPs exposure inhibited the uptake of essential elements by roots due to pore blockage and hetero-aggregation of opposite charges. The study also revealed that MPs could penetrate the root cortex and be transported to shoots through transpiration in xylem vessels. The toxic effects of MPs on plants were found to be determined by the types of surface functional groups rather than just their accumulation contents. Overall, this study emphasizes the importance of understanding the toxic effects and uptake mechanisms of MPs in agricultural ecosystems.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Review
Cell Biology
Tautvydas Paskevicius, Rabih Abou Farraj, Marek Michalak, Luis B. Agellon
Summary: Calnexin is an integral ER membrane protein with distinct domains in the ER lumen and cytosol. It acts as a chaperone for folding and quality control of proteins, similar to calreticulin. Recent studies have shown that the cytosolic domain of calnexin undergoes post-translational modifications and interacts with various proteins, suggesting its role in coordinating ER functions with cytosolic events.
Article
Microbiology
Claire M. Grison, Stephen Jackson, Sylvain Merlot, Alan Dobson, Claude Grison
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2015)
Article
Biochemistry & Molecular Biology
Alexandre Grondin, Olivier Rodrigues, Lionel Verdoucq, Sylvain Merlot, Nathalie Leonhardt, Christophe Maurel
Article
Plant Sciences
Viviane Mary, Magali Schnell Ramos, Cynthia Gillet, Amanda L. Socha, Jerome Giraudat, Astrid Agorio, Sylvain Merlot, Colin Clairet, Sun A. Kim, Tracy Punshon, Mary Lou Guerinot, Sebastien Thomine
Article
Multidisciplinary Sciences
Astrid Agorio, Jerome Giraudat, Michele Wolfe Bianchi, Jessica Marion, Christelle Espagne, Loren Castaings, Francoise Lelievre, Catherine Curie, Sebastien Thomine, Sylvain Merlot
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2017)
Article
Plant Sciences
Emma L. Bastow, Vanesa S. Garcia de la Torre, Andrew E. Maclean, Robert T. Green, Sylvain Merlot, Sebastien Thomine, Janneke Balk
Article
Plant Sciences
Sylvain Merlot, Laure Hannibal, Sara Martins, Laetitia Martinelli, Hamid Amir, Michel Lebrun, Sebastien Thomine
JOURNAL OF EXPERIMENTAL BOTANY
(2014)
Article
Plant Sciences
Florina Vlad, Marie-Jo Droillard, Benoit Valot, Mehdi Khafif, Americo Rodrigues, Mathias Brault, Michel Zivy, Pedro L. Rodriguez, Sylvain Merlot, Christiane Lauriere
Article
Biochemistry & Molecular Biology
Stefanie Wege, Alexis De Angeli, Marie-Jo Droillard, Laetitia Kroniewicz, Sylvain Merlot, David Cornu, Franco Gambale, Enrico Martinoia, Helene Barbier-Brygoo, Sebastien Thomine, Nathalie Leonhardt, Sophie Filleur
Article
Plant Sciences
Tanguy Jaffre, Yohan Pillon, Sebastien Thomine, Sylvain Merlot
FRONTIERS IN PLANT SCIENCE
(2013)
Article
Ecology
Yohan Pillon, Dubiel Alfonso Gonzalez, Herizo Randriambanona, Porter P. Lowry, Tanguy Jaffre, Sylvain Merlot
JOURNAL OF BIOGEOGRAPHY
(2019)
Article
Plant Sciences
Vanesa S. Garcia de la Torre, Clarisse Majorel-Loulergue, Guillem J. Rigaill, Dubiel Alfonso-Gonzalez, Ludivine Soubigou-Taconnat, Yohan Pillon, Louise Barreau, Sebastien Thomine, Bruno Fogliani, Valerie Burtet-Sarramegna, Sylvain Merlot
Summary: The research suggests that many plant species growing on metalliferous soils can accumulate and tolerate high levels of nickel, a trait that has evolved independently multiple times in different plant families. Analysis reveals the presence of genes encoding functions related to nickel hyperaccumulation in these species, including biosynthesis of specialized metabolites and cell wall organization. Additionally, high expression of IREG/Ferroportin transporters is recurrently associated with nickel hyperaccumulation in plants.
Editorial Material
Plant Sciences
Sebastien Thomine, Sylvain Merlot
Article
Plant Sciences
Karine Gotty, Gael J. Kergoat, Pierre Jouannais, Vanessa Invernon, Sylvain Merlot, Yohan Pillon
Summary: Alseuosmineae is a relict lineage in Oceania with high diversity in New Caledonia, especially on ultramafic substrates. Molecular and metal concentration analyses indicate that this clade started diversifying about 75-80 million years ago, with slower net diversification rates compared to other Asterales groups. It is hypothesized that adaptation to ultramafic substrates and metal accumulation contribute to the survival of Alseuosmineae.
PLANT ECOLOGY & DIVERSITY
(2022)
Article
Biochemistry & Molecular Biology
Celestine Belloeil, Pierre Jouannais, Charles Malfaisan, Rolando Reyes Fernandez, Severine Lopez, Dulce Montserrat Navarrete Gutierrez, Swann Maeder-Pras, Paola Villanueva, Romane Tisserand, Melina Gallopin, Dubiel Alfonso-Gonzalez, Ilsa M. Fuentes Marrero, Serge Muller, Vanessa Invernon, Yohan Pillon, Guillaume Echevarria, Rosalina Berazain Iturralde, Sylvain Merlot
Summary: This study analyzed metal accumulation in a wide diversity of Neotropical flora using X-ray fluorescence technology and discovered new species with high metal accumulation capacity. These findings will be instrumental in supporting the development of phytotechnologies to mitigate soil metal pollution in the region.
