Bacteriophage Therapeutics: A Primer for Clinicians on Phage‐Antibiotic Combinations

Dalbavancin Alone and in Combination with Ceftaroline against Four Different Phenotypes of Staphylococcus aureus in a PK/PD Model

(2019) R. Kebriaei et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Phage Therapy in the Postantibiotic Era

(2019) Fernando L. Gordillo Altamirano et al.   CLINICAL MICROBIOLOGY REVIEWS

Adjunct phage treatment enhances the effectiveness of low antibiotic concentration against Staphylococcus aureus biofilms in vitro

(2019) James Dickey et al.   PLoS One

Design and Preclinical Development of a Phage Product for the Treatment of Antibiotic-Resistant Staphylococcus aureus Infections

(2019) Susan Lehman et al.   Viruses-Basel

Successful treatment of antibiotic resistant poly-microbial bone infection with bacteriophages and antibiotics combination

(2019) Ran Nir-Paz et al.   CLINICAL INFECTIOUS DISEASES

The Infectious Diseases Society of America’s 10 × ’20 Initiative (Ten New Systemic Antibacterial Agents FDA-approved by 2020): Is 20 × ’20 a Possibility?

(2019) George H Talbot et al.   CLINICAL INFECTIOUS DISEASES

Compassionate use of unauthorized drugs: Legal regulations and ethical challenges

(2019) Jan Borysowski et al.   European Journal of Internal Medicine

Successful adjunctive use of bacteriophage therapy for treatment of multidrug-resistant Pseudomonas aeruginosa infection in a cystic fibrosis patient

(2019) Nancy Law et al.   INFECTION

Engineered bacteriophages for treatment of a patient with a disseminated drug-resistant Mycobacterium abscessus

(2019) Rebekah M. Dedrick et al.   NATURE MEDICINE

Current State of Compassionate Phage Therapy

(2019) McCallin et al.   Viruses-Basel

Early clinical experience of bacteriophage therapy in 3 lung transplant recipients

(2019) Saima Aslam et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Piperacillin and ceftazidime produce the strongest synergistic phage–antibiotic effect in Pseudomonas aeruginosa

(2018) Jumpei Uchiyama et al.   ARCHIVES OF VIROLOGY

Combined bacteriophages and antibiotics as an efficient therapy against VRE Enterococcus faecalis in a mouse model

(2018) Daniel Gelman et al.   RESEARCH IN MICROBIOLOGY

In Vitro Characteristics of Phages to Guide ‘Real Life’ Phage Therapy Suitability

(2018) Eoghan Casey et al.   Viruses-Basel

Resistance Development to Bacteriophages Occurring during Bacteriophage Therapy

(2018) Frank Oechslin   Viruses-Basel

Loss-of-Function Mutations in epaR Confer Resistance to ϕNPV1 Infection in Enterococcus faecalis OG1RF

(2018) Khang Ho et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Enhanced antibacterial effect of the novel T4-like bacteriophage KARL-1 in combination with antibiotics against multi-drug resistant Acinetobacter baumannii

(2018) Mathias Jansen et al.   Scientific Reports

Short Course Antibiotic Therapy—Replacing Constantine Units with “Shorter Is Better”

(2018) Noah Wald-Dickler et al.   CLINICAL INFECTIOUS DISEASES

Efficacy and tolerability of a cocktail of bacteriophages to treat burn wounds infected by Pseudomonas aeruginosa (PhagoBurn): a randomised, controlled, double-blind phase 1/2 trial

(2018) Patrick Jault et al.   LANCET INFECTIOUS DISEASES

Effects of single and combined use of bacteriophages and antibiotics to inactivate Escherichia coli

(2017) Nádia Valério et al.   VIRUS RESEARCH

Synergy and Order Effects of Antibiotics and Phages in Killing Pseudomonas aeruginosa Biofilms

(2017) Waqas Nasir Chaudhry et al.   PLoS One

Oral Phage Therapy of Acute Bacterial Diarrhea With Two Coliphage Preparations: A Randomized Trial in Children From Bangladesh

(2016) Shafiqul Alam Sarker et al.   EBioMedicine

Phage selection restores antibiotic sensitivity in MDR Pseudomonas aeruginosa

(2016) Benjamin K. Chan et al.   Scientific Reports

Microbiological effects of sublethal levels of antibiotics

(2014) Dan I. Andersson et al.   NATURE REVIEWS MICROBIOLOGY

A Window of Opportunity to Control the Bacterial Pathogen Pseudomonas aeruginosa Combining Antibiotics and Phages

(2014) Clara Torres-Barceló et al.   PLoS One

Effect of Bacteriophage Infection in Combination with Tobramycin on the Emergence of Resistance in Escherichia coli and Pseudomonas aeruginosa Biofilms

(2014) Lindsey Coulter et al.   Viruses-Basel

The habits of highly effective phages: population dynamics as a framework for identifying therapeutic phages

(2014) James J. Bull et al.   Frontiers in Microbiology

Bacteriophage therapy of venous leg ulcers in humans: results of a phase I safety trial

(2014) D.D. Rhoads et al.   Journal of Wound Care

Learning from Bacteriophages - Advantages and Limitations of Phage and Phage-Encoded Protein Applications

(2013) Zuzanna Drulis-Kawa et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Phage cocktails and the future of phage therapy

(2013) Benjamin K Chan et al.   Future Microbiology

Bacteriophage Therapy in Implant-Related Infections

(2013) Cengiz Yilmaz et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Co-Therapy Using Lytic Bacteriophage and Linezolid: Effective Treatment in Eliminating Methicillin Resistant Staphylococcus aureus (MRSA) from Diabetic Foot Infections

(2013) Sanjay Chhibber et al.   PLoS One

A historical overview of bacteriophage therapy as an alternative to antibiotics for the treatment of bacterial pathogens

(2013) Xavier Wittebole et al.   Virulence

Synergistic phage-antibiotic combinations for the control ofEscherichia colibiofilmsin vitro

(2012) Elizabeth M. Ryan et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Synergistic Action of Gentamicin and Bacteriophage in a Continuous Culture Population of Staphylococcus aureus

(2012) Amy E. Kirby   PLoS One

Phage-antibiotic synergism: a possible approach to combatting Pseudomonas aeruginosa

(2012) Petar Knezevic et al.   RESEARCH IN MICROBIOLOGY

Characterization of inducedStaphylococcus aureusbacteriophage SAP-26 and its anti-biofilm activity with rifampicin

(2011) Marzia Rahman et al.   BIOFOULING

Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance

(2011) A.-P. Magiorakos et al.   CLINICAL MICROBIOLOGY AND INFECTION

Bacteriophage therapy for refractory Pseudomonas aeruginosa urinary tract infection

(2011) A. Khawaldeh et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Daptomycin-Oxacillin Combinations in Treatment of Experimental Endocarditis Caused by Daptomycin-Nonsusceptible Strains of Methicillin-Resistant Staphylococcus aureus with Evolving Oxacillin Susceptibility (the "Seesaw Effect")

(2010) S.-J. Yang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structural changes induced by a lytic bacteriophage make ciprofloxacin effective against older biofilm of Klebsiella pneumoniae

(2010) Vivek Verma et al.   BIOFOULING

Phage Therapy in Clinical Practice: Treatment of Human Infections

(2010) Elizabeth Kutter et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Bacteriophage resistance mechanisms

(2010) Simon J. Labrie et al.   NATURE REVIEWS MICROBIOLOGY

A controlled clinical trial of a therapeutic bacteriophage preparation in chronic otitis due to antibiotic-resistantPseudomonas aeruginosa; a preliminary report of efficacy

(2009) A. Wright et al.   CLINICAL OTOLARYNGOLOGY

The tail sheath structure of bacteriophage T4: a molecular machine for infecting bacteria

(2009) Anastasia A Aksyuk et al.   EMBO JOURNAL

Restricting ciprofloxacin-induced resistant variant formation in biofilm of Klebsiella pneumoniae B5055 by complementary bacteriophage treatment

(2009) V. Verma et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Amoxicillin and specific bacteriophage can be used together for eradication of biofilm of Klebsiella pneumoniae B5055

(2009) Manmeet Sakshi Bedi et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Therapeutic potential of bacteriophage in treating Klebsiella pneumoniae B5055-mediated lobar pneumonia in mice

(2008) S. Chhibber et al.   JOURNAL OF MEDICAL MICROBIOLOGY