A bipartite structural organization defines the SERINC family of HIV-1 restriction factors

CD4 occupancy triggers sequential pre-fusion conformational states of the HIV-1 envelope trimer with relevance for broadly neutralizing antibody activity

(2019) Branislav Ivan et al.   PLOS BIOLOGY

The retroviral accessory proteins S2, Nef, and glycoMA use similar mechanisms for antagonizing the host restriction factor SERINC5

(2019) Iqbal Ahmad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Mechanism of HIV-1 Entry

(2019) Bing Chen   TRENDS IN MICROBIOLOGY

Faster Simulations with a 5 fs Time Step for Lipids in the CHARMM Force Field

(2018) Karina Olesen et al.   Journal of Chemical Theory and Computation

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Localization to detergent-resistant membranes and HIV-1 core entry inhibition correlate with HIV-1 restriction by SERINC5

(2018) Bianca Schulte et al.   VIROLOGY

Real-space refinement in PHENIX for cryo-EM and crystallography

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

Inside job: how the ESCRTs release HIV-1 from infected cells

(2018) James H. Hurley et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

An N-glycosylated form of SERINC5 is specifically incorporated into HIV-1 virions

(2018) Shilpi Sharma et al.   JOURNAL OF VIROLOGY

Structure of the membrane proximal external region of HIV-1 envelope glycoprotein

(2018) Qingshan Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The host-cell restriction factor SERINC5 restricts HIV-1 infectivity without altering the lipid composition and organization of viral particles

(2017) Birthe Trautz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SERINC5 protein inhibits HIV-1 fusion pore formation by promoting functional inactivation of envelope glycoproteins

(2017) Chetan Sood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disruption of Serinc1, which facilitates serine-derived lipid synthesis, fails to alter macrophage function, lymphocyte proliferation or autoimmune disease susceptibility

(2017) Edward P.F. Chu et al.   MOLECULAR IMMUNOLOGY

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Effect of HIV-1 Env on SERINC5 Antagonism

(2016) Saina Beitari et al.   JOURNAL OF VIROLOGY

High resolution single particle refinement in EMAN2.1

(2016) James M. Bell et al.   METHODS

High-resolution mass spectrometry of small molecules bound to membrane proteins

(2016) Joseph Gault et al.   NATURE METHODS

S2 from equine infectious anemia virus is an infectivity factor which counteracts the retroviral inhibitors SERINC5 and SERINC3

(2016) Ajit Chande et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer

(2016) J. H. Lee et al.   SCIENCE

Bayesian Deconvolution of Mass and Ion Mobility Spectra: From Binary Interactions to Polydisperse Ensembles

(2015) Michael T. Marty et al.   ANALYTICAL CHEMISTRY

SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef

(2015) Yoshiko Usami et al.   NATURE

HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation

(2015) Annachiara Rosa et al.   NATURE

EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy

(2015) Benjamin A Barad et al.   NATURE METHODS

CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data

(2013) Jing Huang et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Genome-wide analyses of borderline personality features

(2013) G H Lubke et al.   MOLECULAR PSYCHIATRY

Rare SERINC2 variants are specific for alcohol dependence in individuals of European descent

(2013) Lingjun Zuo et al.   Pharmacogenetics and Genomics

New Target Genes of MITF-Induced microRNA-211 Contribute to Melanoma Cell Invasion

(2013) Christiane Margue et al.   PLoS One

HIV-1 Nef Responsiveness Is Determined by Env Variable Regions Involved in Trimer Association and Correlates with Neutralization Sensitivity

(2013) Yoshiko Usami et al.   Cell Reports

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Prevention of overfitting in cryo-EM structure determination

(2012) Sjors H W Scheres et al.   NATURE METHODS

From Coarse Grained to Atomistic: A Serial Multiscale Approach to Membrane Protein Simulations

(2011) Phillip J. Stansfeld et al.   Journal of Chemical Theory and Computation

Direct Antibody Access to the HIV-1 Membrane-Proximal External Region Positively Correlates with Neutralization Sensitivity

(2011) B. K. Chakrabarti et al.   JOURNAL OF VIROLOGY

OPM database and PPM web server: resources for positioning of proteins in membranes

(2011) Mikhail A. Lomize et al.   NUCLEIC ACIDS RESEARCH

Nef Decreases HIV-1 Sensitivity to Neutralizing Antibodies that Target the Membrane-proximal External Region of TMgp41

(2011) Rachel P.J. Lai et al.   PLoS Pathogens

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The MARTINI Coarse-Grained Force Field: Extension to Proteins

(2008) Luca Monticelli et al.   Journal of Chemical Theory and Computation

A one-step SYBR Green I-based product-enhanced reverse transcriptase assay for the quantitation of retroviruses in cell culture supernatants

(2008) Massimo Pizzato et al.   JOURNAL OF VIROLOGICAL METHODS