标题
Dynamic responses of the haematopoietic stem cell niche to diverse stresses
作者
关键词
-
出版物
NATURE CELL BIOLOGY
Volume 22, Issue 1, Pages 7-17
出版商
Springer Science and Business Media LLC
发表日期
2020-01-07
DOI
10.1038/s41556-019-0444-9
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia
- (2019) Ninib Baryawno et al. CELL
- The bone marrow microenvironment at single-cell resolution
- (2019) Anastasia N. Tikhonova et al. NATURE
- Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment
- (2018) Simranpreet Kaur et al. BLOOD
- Imaging methods used to study mouse and human HSC niches: Current and emerging technologies
- (2018) Gavin Tjin et al. BONE
- Intercellular mitochondria trafficking highlighting the dual role of mesenchymal stem cells as both sensors and rescuers of tissue injury
- (2018) Anne-Marie Rodriguez et al. CELL CYCLE
- CD150 high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine
- (2018) Yuichi Hirata et al. Cell Stem Cell
- Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML
- (2018) Delfim Duarte et al. Cell Stem Cell
- Niches for Hematopoietic Stem Cells and Their Progeny
- (2018) Qiaozhi Wei et al. IMMUNITY
- Chemotherapy alters the increased numbers of myeloid-derived suppressor and regulatory T cells in children with acute lymphoblastic leukemia
- (2018) Mohamed Labib Salem et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Blocking IFNAR1 inhibits multiple myeloma–driven Treg expansion and immunosuppression
- (2018) Yawara Kawano et al. JOURNAL OF CLINICAL INVESTIGATION
- Bone Marrow-derived CD8+ T Cells From Pediatric Leukemia Patients Express PD1 and Expand Ex Vivo Following Induction Chemotherapy
- (2018) Katie Palen et al. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
- CAR T cell–induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade
- (2018) Theodoros Giavridis et al. NATURE MEDICINE
- A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche
- (2018) Jlenia Guarnerio et al. Nature Communications
- Defining the in vivo characteristics of acute myeloid leukemia cells behavior by intravital imaging
- (2018) Delfim Duarte et al. IMMUNOLOGY AND CELL BIOLOGY
- Lifelong dietary intervention does not affect hematopoietic stem cell function
- (2017) Seka Lazare et al. EXPERIMENTAL HEMATOLOGY
- Role of mTORC1–S6K1 signaling pathway in regulation of hematopoietic stem cell and acute myeloid leukemia
- (2017) Joydeep Ghosh et al. EXPERIMENTAL HEMATOLOGY
- Amino acid–insensitive mTORC1 regulation enables nutritional stress resilience in hematopoietic stem cells
- (2017) Demetrios Kalaitzidis et al. JOURNAL OF CLINICAL INVESTIGATION
- Reactive Oxygen Species–Producing Myeloid Cells Act as a Bone Marrow Niche for Sterile Inflammation–Induced Reactive Granulopoiesis
- (2017) Haiyan Zhu et al. JOURNAL OF IMMUNOLOGY
- Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis
- (2017) Aurélie Hérault et al. NATURE
- Ascorbate regulates haematopoietic stem cell function and leukaemogenesis
- (2017) Michalis Agathocleous et al. NATURE
- Three-dimensional map of nonhematopoietic bone and bone-marrow cells and molecules
- (2017) Daniel L Coutu et al. NATURE BIOTECHNOLOGY
- Cell–matrix signals specify bone endothelial cells during developmental osteogenesis
- (2017) Urs H. Langen et al. NATURE CELL BIOLOGY
- Acute myeloid leukaemia disrupts endogenous myelo-erythropoiesis by compromising the adipocyte bone marrow niche
- (2017) Allison L. Boyd et al. NATURE CELL BIOLOGY
- Bone marrow adipocytes promote the regeneration of stem cells and haematopoiesis by secreting SCF
- (2017) Bo O. Zhou et al. NATURE CELL BIOLOGY
- Differential cytokine contributions of perivascular haematopoietic stem cell niches
- (2017) Noboru Asada et al. NATURE CELL BIOLOGY
- Granulocyte-derived TNFα promotes vascular and hematopoietic regeneration in the bone marrow
- (2017) Emily Bowers et al. NATURE MEDICINE
- T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow
- (2017) Arielle Glatman Zaretsky et al. Cell Reports
- Hypoxia and Mucosal Inflammation
- (2016) Sean P. Colgan et al. Annual Review of Pathology-Mechanisms of Disease
- HIF-1 regulates the interaction of chronic lymphocytic leukemia cells with the tumor microenvironment
- (2016) R. Valsecchi et al. BLOOD
- Protective mitochondrial transfer from bone marrow stromal cells to acute myeloid leukemic cells during chemotherapy
- (2016) R. Moschoi et al. BLOOD
- Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche
- (2016) Haobin Ye et al. Cell Stem Cell
- Heterogeneity of the bone marrow niche
- (2016) Vionnie W.C. Yu et al. CURRENT OPINION IN HEMATOLOGY
- Macrophages: Key regulators of steady-state and demand-adapted hematopoiesis
- (2016) Amanda McCabe et al. EXPERIMENTAL HEMATOLOGY
- IFNα-mediated remodeling of endothelial cells in the bone marrow niche
- (2016) Áine M. Prendergast et al. HAEMATOLOGICA
- Indoleamine 2,3-dioxygenase and regulatory T cells in acute myeloid leukemia
- (2016) Iman Mansour et al. Hematology
- Sepsis-Induced Osteoblast Ablation Causes Immunodeficiency
- (2016) Asuka Terashima et al. IMMUNITY
- Intravital multiphoton photoconversion with a cell membrane dye
- (2016) Raphaël Turcotte et al. Journal of Biophotonics
- A novel hypoxia-selective epigenetic agent RRx-001 triggers apoptosis and overcomes drug resistance in multiple myeloma cells
- (2016) D Sharma Das et al. LEUKEMIA
- T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments
- (2016) Edwin D. Hawkins et al. NATURE
- Distinct bone marrow blood vessels differentially regulate haematopoiesis
- (2016) Tomer Itkin et al. NATURE
- Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment
- (2016) Lei Dong et al. NATURE
- Age-dependent modulation of vascular niches for haematopoietic stem cells
- (2016) Anjali P. Kusumbe et al. NATURE
- Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation
- (2016) Zhigang Lu et al. NATURE MEDICINE
- Granulocyte-like myeloid derived suppressor cells (G-MDSC) are increased in multiple myeloma and are driven by dysfunctional mesenchymal stem cells (MSC)
- (2016) Cesarina Giallongo et al. Oncotarget
- Chronic Infection Depletes Hematopoietic Stem Cells through Stress-Induced Terminal Differentiation
- (2016) Katie A. Matatall et al. Cell Reports
- Systematic tracking of altered haematopoiesis during sporozoite-mediated malaria development reveals multiple response points
- (2016) Maria L. Vainieri et al. Open Biology
- IFNα-mediated remodeling of endothelial cells in the bone marrow niche
- (2016) Áine M. Prendergast et al. HAEMATOLOGICA
- Mesenchymal Stem Cells (MSC) Regulate Activation of Granulocyte-Like Myeloid Derived Suppressor Cells (G-MDSC) in Chronic Myeloid Leukemia Patients
- (2016) Cesarina Giallongo et al. PLoS One
- Granulocyte colony-stimulating factor reprograms bone marrow stromal cells to actively suppress B lymphopoiesis in mice
- (2015) R. B. Day et al. BLOOD
- Targeting the leukemia cell metabolism by the CPT1a inhibition: functional preclinical effects in leukemias
- (2015) M. R. Ricciardi et al. BLOOD
- Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia
- (2015) Alicia Cole et al. CANCER CELL
- CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphoblastic Leukemia
- (2015) Diana Passaro et al. CANCER CELL
- CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance
- (2015) Lauren A. Pitt et al. CANCER CELL
- Hypoxia-Activated Prodrug TH-302 Targets Hypoxic Bone Marrow Niches in Preclinical Leukemia Models
- (2015) J. Benito et al. CLINICAL CANCER RESEARCH
- Myeloid Cell-Derived Reactive Oxygen Species Externally Regulate the Proliferation of Myeloid Progenitors in Emergency Granulopoiesis
- (2015) Hyun-Jeong Kwak et al. IMMUNITY
- Vascular endothelial cell Toll-like receptor pathways in sepsis
- (2015) Samira Khakpour et al. Innate Immunity
- Macrophage-Lineage Cells Negatively Regulate the Hematopoietic Stem Cell Pool in Response to Interferon Gamma at Steady State and During Infection
- (2015) Amanda McCabe et al. STEM CELLS
- Cytotoxic activities of CD8+ T cells collaborate with macrophages to protect against blood-stage murine malaria
- (2015) Takashi Imai et al. eLife
- In vivo time-lapse imaging shows diverse niche engagement by quiescent and naturally activated hematopoietic stem cells
- (2014) N. M. Rashidi et al. BLOOD
- CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs
- (2014) R. Jitschin et al. BLOOD
- Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis
- (2014) S. Boettcher et al. BLOOD
- Consequences of irradiation on bone and marrow phenotypes, and its relation to disruption of hematopoietic precursors
- (2014) Danielle E. Green et al. BONE
- Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow
- (2014) Bo O. Zhou et al. Cell Stem Cell
- Cytotoxic CD8+ T Cells Stimulate Hematopoietic Progenitors by Promoting Cytokine Release from Bone Marrow Mesenchymal Stromal Cells
- (2014) Christian M. Schürch et al. Cell Stem Cell
- Osterix Marks Distinct Waves of Primitive and Definitive Stromal Progenitors during Bone Marrow Development
- (2014) Toshihide Mizoguchi et al. DEVELOPMENTAL CELL
- G-CSF regulates hematopoietic stem cell activity, in part, through activation of Toll-like receptor signaling
- (2014) L G Schuettpelz et al. LEUKEMIA
- PIM Kinases Are Essential for Chronic Lymphocytic Leukemia Cell Survival (PIM2/3) and CXCR4-Mediated Microenvironmental Interactions (PIM1)
- (2014) S. Decker et al. MOLECULAR CANCER THERAPEUTICS
- Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms
- (2014) Lorena Arranz et al. NATURE
- Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts
- (2014) Aruna Kode et al. NATURE
- Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
- (2014) Anjali P. Kusumbe et al. NATURE
- Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells
- (2014) Meng Zhao et al. NATURE MEDICINE
- Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
- (2014) Shannon L. Maude et al. NEW ENGLAND JOURNAL OF MEDICINE
- Myeloid Derived Suppressor Cells (MDSCs) Are Increased and Exert Immunosuppressive Activity Together with Polymorphonuclear Leukocytes (PMNs) in Chronic Myeloid Leukemia Patients
- (2014) Cesarina Giallongo et al. PLoS One
- Plasmodium falciparum transmission stages accumulate in the human bone marrow
- (2014) R. Joice et al. Science Translational Medicine
- Raman spectroscopy demonstrates prolonged alteration of bone chemical composition following extremity localized irradiation
- (2013) Bo Gong et al. BONE
- Heparanase inhibits osteoblastogenesis and shifts bone marrow progenitor cell fate in myeloma bone disease
- (2013) Jian Ruan et al. BONE
- Adipocytes Cause Leukemia Cell Resistance to L-Asparaginase via Release of Glutamine
- (2013) E. A. Ehsanipour et al. CANCER RESEARCH
- Rhythmic Modulation of the Hematopoietic Niche through Neutrophil Clearance
- (2013) María Casanova-Acebes et al. CELL
- Deciphering Hematopoietic Stem Cells in Their Niches: A Critical Appraisal of Genetic Models, Lineage Tracing, and Imaging Strategies
- (2013) Chacko Joseph et al. Cell Stem Cell
- Myeloproliferative Neoplasia Remodels the Endosteal Bone Marrow Niche into a Self-Reinforcing Leukemic Niche
- (2013) Koen Schepers et al. Cell Stem Cell
- BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells
- (2013) Eleni D. Lagadinou et al. Cell Stem Cell
- Toxicity management for patients receiving novel T-cell engaging therapies
- (2013) David M. Barrett et al. CURRENT OPINION IN PEDIATRICS
- Bone marrow osteoblast vulnerability to chemotherapy
- (2013) Marieta Gencheva et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Induction of myelodysplasia by myeloid-derived suppressor cells
- (2013) Xianghong Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- Cytotoxic T cells induce proliferation of chronic myeloid leukemia stem cells by secreting interferon-γ
- (2013) Christian Schürch et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Insufficient stromal support in MDS results from molecular and functional deficits of mesenchymal stromal cells
- (2013) S Geyh et al. LEUKEMIA
- CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance
- (2013) Adam Greenbaum et al. NATURE
- Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches
- (2013) Lei Ding et al. NATURE
- Arteriolar niches maintain haematopoietic stem cell quiescence
- (2013) Yuya Kunisaki et al. NATURE
- Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration
- (2013) Daniel Lucas et al. NATURE MEDICINE
- Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia
- (2013) Stephan A. Grupp et al. NEW ENGLAND JOURNAL OF MEDICINE
- Tracking Single Cells in Live Animals Using a Photoconvertible Near-Infrared Cell Membrane Label
- (2013) Alicia L. Carlson et al. PLoS One
- Osterix-Cre Labeled Progenitor Cells Contribute to the Formation and Maintenance of the Bone Marrow Stroma
- (2013) Yaling Liu et al. PLoS One
- Endothelial Jagged-1 Is Necessary for Homeostatic and Regenerative Hematopoiesis
- (2013) Michael G. Poulos et al. Cell Reports
- FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation
- (2012) T. Itkin et al. BLOOD
- Demand-adapted regulation of early hematopoiesis in infection and inflammation
- (2012) H. Takizawa et al. BLOOD
- Altered Microenvironmental Regulation of Leukemic and Normal Stem Cells in Chronic Myelogenous Leukemia
- (2012) Bin Zhang et al. CANCER CELL
- Regulation of Hematopoietic Stem and Progenitor Cell Mobilization by Cholesterol Efflux Pathways
- (2012) Marit Westerterp et al. Cell Stem Cell
- Vascular endothelial growth factor signaling in acute myeloid leukemia
- (2012) Kim R. Kampen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Generation and characterization ofOsterix-Cherry reporter mice
- (2012) Sara Strecker et al. GENESIS
- Second Malignant Neoplasms: Assessment and Strategies for Risk Reduction
- (2012) Marie E. Wood et al. JOURNAL OF CLINICAL ONCOLOGY
- Stromal-derived IL-6 alters the balance of myeloerythroid progenitors during Toxoplasma gondii infection
- (2012) David B. Chou et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Multiple myeloma induces the immunosuppressive capacity of distinct myeloid-derived suppressor cell subpopulations in the bone marrow
- (2012) E Van Valckenborgh et al. LEUKEMIA
- Endothelial and perivascular cells maintain haematopoietic stem cells
- (2012) Lei Ding et al. NATURE
- Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia
- (2012) Wan Zhang et al. NATURE CELL BIOLOGY
- Increased T Regulatory Cells Are Associated with Adverse Clinical Features and Predict Progression in Multiple Myeloma
- (2012) Karthick Raja Muthu Raja et al. PLoS One
- Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia
- (2011) B. J. Frisch et al. BLOOD
- Bone Marrow Stroma-Secreted Cytokines Protect JAK2V617F-Mutated Cells from the Effects of a JAK2 Inhibitor
- (2011) T. Manshouri et al. CANCER RESEARCH
- Human Tumor Cells Killed by Anthracyclines Induce a Tumor-Specific Immune Response
- (2011) J. Fucikova et al. CANCER RESEARCH
- Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche
- (2011) Satoshi Yamazaki et al. CELL
- Bone Marrow Mesenchymal Stem and Progenitor Cells Induce Monocyte Emigration in Response to Circulating Toll-like Receptor Ligands
- (2011) Chao Shi et al. IMMUNITY
- Chronic Immune Stimulation Might Act As a Trigger for the Development of Acute Myeloid Leukemia or Myelodysplastic Syndromes
- (2011) Sigurdur Y. Kristinsson et al. JOURNAL OF CLINICAL ONCOLOGY
- Hemophagocytosis causes a consumptive anemia of inflammation
- (2011) Erin E. Zoller et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Bone marrow CD169+macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche
- (2011) Andrew Chow et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The serine/threonine kinase Pim-2 is a novel anti-apoptotic mediator in myeloma cells
- (2011) J Asano et al. LEUKEMIA
- In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche
- (2011) Joji Fujisaki et al. NATURE
- CXCL12 secretion by bone marrow stromal cells is dependent on cell contact and mediated by connexin-43 and connexin-45 gap junctions
- (2011) Amir Schajnovitz et al. NATURE IMMUNOLOGY
- Irradiation induces bone injury by damaging bone marrow microenvironment for stem cells
- (2011) X. Cao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice
- (2011) M. Michaud et al. SCIENCE
- Angiogenesis: A Target in Solid Tumors, Also in Leukemia?
- (2011) T. Schmidt et al. Hematology-American Society of Hematology Education Program
- Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs
- (2010) I. G. Winkler et al. BLOOD
- Intensive chemotherapy for acute myeloid leukemia differentially affects circulating TC1, TH1, TH17 and TREG cells
- (2010) Elisabeth Ersvaer et al. BMC IMMUNOLOGY
- Flk1-GFP BAC Tg Mice: An Animal Model for the Study of Blood Vessel Development
- (2010) Hiroyuki ISHITOBI et al. EXPERIMENTAL ANIMALS
- Autoimmunity and the risk of myeloproliferative neoplasms
- (2010) S. Y. Kristinsson et al. HAEMATOLOGICA
- Bone marrow mesenchymal stromal cells non-selectively protect chronic myeloid leukemia cells from imatinib-induced apoptosis via the CXCR4/CXCL12 axis
- (2010) F. Vianello et al. HAEMATOLOGICA
- Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection
- (2010) Megan T. Baldridge et al. NATURE
- Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
- (2010) Marc H. G. P. Raaijmakers et al. NATURE
- Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
- (2010) Simón Méndez-Ferrer et al. NATURE
- Calreticulin exposure on malignant blasts predicts a cellular anticancer immune response in patients with acute myeloid leukemia
- (2010) M Wemeau et al. Cell Death & Disease
- Genetic Control of Bone Formation
- (2009) Gerard Karsenty et al. Annual Review of Cell and Developmental Biology
- The leukemic stem cell niche: current concepts and therapeutic opportunities
- (2009) S. W. Lane et al. BLOOD
- Adipocytes Impair Leukemia Treatment in Mice
- (2009) J. W. Behan et al. CANCER RESEARCH
- Engraftment and Reconstitution of Hematopoiesis Is Dependent on VEGFR2-Mediated Regeneration of Sinusoidal Endothelial Cells
- (2009) Andrea T. Hooper et al. Cell Stem Cell
- Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment
- (2009) Olaia Naveiras et al. NATURE
- Total-Body Irradiation of Postpubertal Mice with137Cs Acutely Compromises the Microarchitecture of Cancellous Bone and Increases Osteoclasts
- (2009) Hisataka Kondo et al. RADIATION RESEARCH
- Myeloid-Derived Suppressor Cells Promote Cross-Tolerance in B-Cell Lymphoma by Expanding Regulatory T Cells
- (2008) P. Serafini et al. CANCER RESEARCH
- Efficient, inducible Cre-recombinase activation in vascular endothelium
- (2008) Suzanne Claxton et al. GENESIS
- Early Increase in Osteoclast Number in Mice after Whole-Body Irradiation with 2 Gy X Rays
- (2008) Jeffrey S. Willey et al. RADIATION RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More