Selective deletion of MyD88 signaling in α-SMA positive cells ameliorates experimental intestinal fibrosis via post-transcriptional regulation

Flagellin-mediated activation of IL-33-ST2 signaling by a pathobiont promotes intestinal fibrosis

(2019) Jin Imai et al.   Mucosal Immunology

Additional Candida albicans administration enhances the severity of dextran sulfate solution induced colitis mouse model through leaky gut-enhanced systemic inflammation and gut-dysbiosis but attenuated by Lactobacillus rhamnosus L34

(2019) Wimonrat Panpetch et al.   Gut Microbes

Fibrosis in ulcerative colitis is directly linked to severity and chronicity of mucosal inflammation

(2018) I. O. Gordon et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

An expert consensus to standardise definitions, diagnosis and treatment targets for anti-fibrotic stricture therapies in Crohn's disease

(2018) F. Rieder et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome

(2018) Noam Jacob et al.   Mucosal Immunology

Mechanisms, Management, and Treatment of Fibrosis in Patients With Inflammatory Bowel Diseases

(2017) Florian Rieder et al.   GASTROENTEROLOGY

Highly Selective Targeting of Hepatic Stellate Cells for Liver Fibrosis Treatment Using a d-Enantiomeric Peptide Ligand of Fn14 Identified by Mirror-Image mRNA Display

(2017) Luying Huang et al.   MOLECULAR PHARMACEUTICS

The anti-microbial peptide TP359 attenuates inflammation in human lung cells infected with Pseudomonas aeruginosa via TLR5 and MAPK pathways

(2017) Ejovwoke F. Dosunmu et al.   PLoS One

Inhibition of MAPK and NF-κB signaling pathways alleviate carbon tetrachloride (CCl4)-induced liver fibrosis in Toll-like receptor 5 (TLR5) deficiency mice

(2016) Ming Shu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pretreatment and Treatment With L-Arginine Attenuate Weight Loss and Bacterial Translocation in Dextran Sulfate Sodium Colitis

(2016) Maria Emília Rabelo Andrade et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Toll-like receptor 5 deficiency attenuates interstitial cardiac fibrosis and dysfunction induced by pressure overload by inhibiting inflammation and the endothelial–mesenchymal transition

(2015) Yuan Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential

(2015) Daniel L. Worthley et al.   CELL

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Why weight? Modelling sample and observational level variability improves power in RNA-seq analyses

(2015) Ruijie Liu et al.   NUCLEIC ACIDS RESEARCH

Fibrosis in Ulcerative Colitis

(2014) Ilyssa O. Gordon et al.   INFLAMMATORY BOWEL DISEASES

Insulin-like Growth Factor-1 Increases Synthesis of Collagen Type I via Induction of the mRNA-binding Protein LARP6 Expression and Binding to the 5′ Stem-loop ofCOL1a1andCOL1a2mRNA

(2014) Christopher D. Blackstock et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Innate Immunity Mediated by TLR5 as a Novel Antiinflammatory Target for Cystic Fibrosis Lung Disease

(2014) C. J. Blohmke et al.   JOURNAL OF IMMUNOLOGY

TLR4 Activation Enhances the PD-L1–Mediated Tolerogenic Capacity of Colonic CD90+Stromal Cells

(2014) Ellen J. Beswick et al.   JOURNAL OF IMMUNOLOGY

The Selective Phosphodiesterase 4 Inhibitor Roflumilast and Phosphodiesterase 3/4 Inhibitor Pumafentrine Reduce Clinical Score and TNF Expression in Experimental Colitis in Mice

(2013) Florian Rieder et al.   PLoS One

Therapy for Fibrotic Diseases: Nearing the Starting Line

(2013) S. L. Friedman et al.   Science Translational Medicine

The Gut Microbiome in Intestinal Fibrosis: Environmental Protector or Provocateur?

(2013) F. Rieder   Science Translational Medicine

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Coding Region Polyadenylation Generates a Truncated tRNA Synthetase that Counters Translation Repression

(2012) Peng Yao et al.   CELL

Detecting differential usage of exons from RNA-seq data

(2012) S. Anders et al.   GENOME RESEARCH

Results of the 2nd scientific workshop of the ECCO (IV): Therapeutic strategies to enhance intestinal healing in inflammatory bowel disease

(2012) Alessandro Armuzzi et al.   Journal of Crohns & Colitis

The microbiome in wound repair and tissue fibrosis

(2012) Brittan S Scales et al.   JOURNAL OF PATHOLOGY

Comparative Metaproteomics and Diversity Analysis of Human Intestinal Microbiota Testifies for Its Temporal Stability and Expression of Core Functions

(2012) Carolin A. Kolmeder et al.   PLoS One

Inflammation-Induced Endothelial-to-Mesenchymal Transition

(2011) Florian Rieder et al.   AMERICAN JOURNAL OF PATHOLOGY

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Toll-like receptors

(2011) Eva Marie Y. Moresco et al.   CURRENT BIOLOGY

Novel engineered targeted interferon-gamma blocks hepatic fibrogenesis in mice

(2011) Ruchi Bansal et al.   HEPATOLOGY

Predictors of fibrostenotic Crohnʼs disease

(2011) Florian Rieder et al.   INFLAMMATORY BOWEL DISEASES

Intestinal fibrosis is reduced by early elimination of inflammation in a mouse model of IBD: Impact of a “Top-Down” approach to intestinal fibrosis in mice

(2011) Laura A. Johnson et al.   INFLAMMATORY BOWEL DISEASES

Bacterial lipopolysaccharide promotes profibrotic activation of intestinal fibroblasts

(2010) J. P. Burke et al.   BRITISH JOURNAL OF SURGERY

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Toll‐like receptors and adaptor molecules in liver disease: Update

(2008) Ekihiro Seki et al.   HEPATOLOGY

Insulin/TOR signaling in growth and homeostasis: A view from the fly world

(2008) Savraj S. Grewal   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY