Article
Materials Science, Textiles
Sareh Abolhassani, Hamed Alipour, Aliakbar Alizadeh, Mohammad Mehdi Nemati, Hanieh Najafi, Omid Alavi
Summary: The study showed that PU-Gel nanofibrous membranes loaded with honey and ZnO-NPs exhibited excellent antibacterial properties against Staphylococcus aureus, Escherichia coli, and Bacillus subtilis. The addition of ZnO-NPs improved the mechanical properties of the membranes, while PU/Gel/H membranes had significant antibacterial effects on E-coli.
JOURNAL OF INDUSTRIAL TEXTILES
(2022)
Article
Biochemistry & Molecular Biology
Rawaiz Khan, Sajjad Haider, Muhammad Umar Aslam Khan, Adnan Haider, Saiful Izwan Abd Razak, Anwarul Hasan, Raees Khan, Mat Uzir Wahit
Summary: The development of advanced multifunctional wound dressings remains a major challenge. In this study, a novel multilayer electrospun nanofibers wound dressing based on diethylenetriamine (DETA) functionalized polyacrylonitrile (PAN), TiO2 nanoparticles (NPs) coating, and bioderived gelatin (Gel) was developed. The ML PAN-DETA-Ct-Gel membrane showed good surface roughness, porosity, and better wettability, and exhibited good cell morphology, proliferation, viability, and antibacterial activity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Materials Science, Multidisciplinary
Yasaman Ghiyasi, Esmaeil Salahi, Hamid Esfahani
Summary: This study investigates the synergy effect of Urtica dioica and ZnO nanoparticles on PCL scaffolds, finding that their incorporation significantly enhances the mechanical properties, antibacterial activity, and hydrophobicity of the scaffolds, while also positively impacting fibroblast cell cytotoxicity.
MATERIALS TODAY COMMUNICATIONS
(2021)
Article
Biochemistry & Molecular Biology
Yarong Lv, Zhongxun Yu, Chenxi Li, Jianwei Zhou, Xujin Lv, Jia Chen, Ming Wei, Jun Liu, Xiaomin Yu, Ce Wang, Ping Hu, Yong Liu
Summary: A series of gelatin-based nanofiber membranes with different curcumin contents were fabricated, showing excellent properties in physical, mechanical, and biocompatibility aspects, indicating the ability to inhibit bacteria and eliminate free radicals, making them promising materials for treating infected wounds.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Multidisciplinary
Manna Li, Zhaofeng Chen, Lixia Yang, Jiayu Li, Jiang Xu, Chao Chen, Qiong Wu, Mengmeng Yang, Tianlong Liu
Summary: An antibacterial coating containing GO/ZnO/Cu2O was successfully sprayed on glass fibers using hydrothermal synthesis and air spraying techniques. The coating exhibited excellent antibacterial properties and stability, with a 100% antibacterial rate against E. coli and S. aureus. The photochemical activity of the coating was significantly improved, which confirmed the photocatalytic/oxidative stress mechanism.
Article
Materials Science, Multidisciplinary
Quanhong Hu, Xingyi Wan, Shaobo Wang, Tian Huang, Xinyang Zhao, Chuyu Tang, Minjia Zheng, Xueyu Wang, Linlin Li
Summary: This study successfully constructed a Janus nanofiber dressing with comprehensive functions of bacterial killing, piezoelectric stimulation to promote fibroblast migration, and unidirectional liquid delivery for wound exudate removal. The Janus dressing, fabricated through layer-by-layer electrostatic spinning technology, exhibits ultrathin, flexible, breathable, and piezoelectric characteristics. Experimental results indicate that the Janus dressing not only drains excess wound exudate and kills local bacteria, but also generates dynamic piezopotential to accelerate wound healing on mice through fibroblast proliferation and migration, collagen deposition, angiogenesis, and re-epithelialization.
SCIENCE CHINA-MATERIALS
(2023)
Article
Materials Science, Textiles
E. San Martin-Martinez, R. Casanas-Pimentel, A. Almaguer-Flores, G. Prado-Prone, A. Garcia-Garcia, C. Landa-Solis, A. Hernandez-Rangel
Summary: The addition of curcumin to PCL-COL composite membranes enhances their mechanical properties and antibacterial effects, making them promising candidates for wound management. The degradation rate and wettability of the membranes are also suitable for skin tissue regeneration.
FIBERS AND POLYMERS
(2022)
Article
Materials Science, Textiles
Md. Abdus Shahid, Ayub Ali, Md. Nur Uddin, Sumon Miah, Syed Maminul Islam, Md. Mohebbullah, Mohammad Salman Ibna Jamal
Summary: A novel multicomponent nanofibrous mat containing polyvinyl alcohol, honey and Curcumin longa extract was successfully prepared, showing better moisture management properties and antibacterial activity. Characterization by scanning electron microscope, bacterial assay, moisture management tester, and FTIR revealed the presence of desired components and promising properties of the fabricated nanofibrous mats.
JOURNAL OF INDUSTRIAL TEXTILES
(2021)
Article
Pharmacology & Pharmacy
Naveed Ahmad, Muhammad Masood Ahmad, Nabil K. Alruwaili, Ziyad Awadh Alrowaili, Fadhel Ahmed Alomar, Sultan Akhtar, Omar Awad Alsaidan, Nabil A. Alhakamy, Ameeduzzafar Zafar, Mohammed Elmowafy, Mohammed H. Elkomy
Summary: This study investigated the application of Arabinoxylan-gelatin blended films as wound dressings for treating chronic wound infections. The results showed that these dressings have good drug release and antibacterial properties, making them suitable for wound protection.
Article
Chemistry, Multidisciplinary
Mingchao Sun, Shaojuan Chen, Peixue Ling, Jianwei Ma, Shaohua Wu
Summary: This study successfully fabricated methacrylated gelatin/poly(L-lactic acid) hybrid nanofiber mats and demonstrated their excellent hydrophilic properties and high water absorption capacity. The UV crosslinking process significantly improved the structural stability and mechanical properties of the nanofiber mats. Crosslinked nanofiber mats with higher MeGel content showed enhanced attachment, growth, and proliferation of human dermal fibroblasts.
Article
Pharmacology & Pharmacy
Gomaa El Fawal, Huoyan Hong, Xiumei Mo, Hongsheng Wang
Summary: The study prepared an antimicrobial and antioxidant scaffold (PCL/Gel/Oil) using electrospinning technique, demonstrating changes in fiber morphology and promising biocompatibility and antibacterial activity for wound dressing application.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Lanlan Wang, Dawei Li, Ying Shen, Feng Liu, Yuqi Zhou, Huiping Wu, Qingsheng Liu, Bingyao Deng
Summary: A novel wound dressing with antibacterial activity and good biocompatibility was developed in this study, showing promising application prospects in the field of medical care.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Nanoscience & Nanotechnology
Rong Chen, Zhiting Liu, Tingting Cui, Xiaoying Zhang, Cai-Feng Wang, Guo-Xing Li, Gefei Wang, Su Chen
Summary: This study presents a gel-nanofiber material that combines the advantages of hydrogels and nanofibers for wound healing. The material overcomes the limitations of low mechanical strength and self-adhesion in hydrogels and the inadequate healing environment created by nanofibers. The gel-nanofiber dressing exhibits high tensile strength, excellent air permeability, self-adhesion, and positive hydrophilicity. It demonstrates good cytocompatibility and antibacterial properties, leading to a high wound-healing rate and substantial granulation growth within a short time period.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Polymer Science
Paola Campa-Siqueiros, Tomas Jesus Madera-Santana, Jesus Fernando Ayala-Zavala, Jaime Lopez-Cervantes, Maria Monica Castillo-Ortega, Pedro Jesus Herrera-Franco, Patricia Quintana-Owen
Summary: Co-electrospun nanofibers of chitosan, polyvinyl alcohol, and eugenol were prepared and characterized, with gelatin as the shell layer. The nanofibers showed good mechanical properties and antimicrobial activity, making them suitable for wound dressings.
Article
Pharmacology & Pharmacy
Laura Tamayo, Paula Santana, Juan C. Forero, Matias Leal, Nicolas Gonzalez, Mauricio Diaz, Nicolas Guiliani, Eugenio Hamm, Marcela Urzua
Summary: The prevalence of chronic and acute wounds presents a challenge for health systems globally. A new study has developed a wound dressing material that releases active agents to prevent infection and promote healing. The material effectively inhibits bacterial growth and promotes fibroblast cell proliferation, making it suitable for non-adherent wound dressings.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Chemistry, Multidisciplinary
Yu Chen, Weipeng Lu, Yanchuan Guo, Yi Zhu, Haojun Lu, Yuxiao Wu
Article
Biochemistry & Molecular Biology
Yu Chen, Yanli Ma, Weipeng Lu, Yanchuan Guo, Yi Zhu, Haojun Lu, Yeping Song
Article
Chemistry, Multidisciplinary
Yu Chen, Weipeng Lu, Yanchuan Guo, Yi Zhu, Haojun Lu, Yeping Song
APPLIED SCIENCES-BASEL
(2019)
Article
Chemistry, Multidisciplinary
Yu Chen, Weipeng Lu, Yanchuan Guo, Yi Zhu, Yeping Song
Article
Chemistry, Multidisciplinary
Yu Chen, Weipeng Lu, Yanchuan Guo, Yi Zhu, Yeping Song
Article
Nanoscience & Nanotechnology
Yi Zhu, Ling Lin, Yu Chen, Yeping Song, Weipeng Lu, Yanchuan Guo
ACS APPLIED MATERIALS & INTERFACES
(2020)
Article
Materials Science, Multidisciplinary
Yi Zhu, Qinghua Wang, Yu Chen, Yuntao Xie, Guohao Han, Shan Liu, Yeping Song, Weipeng Lu, Yanchuan Guo
Summary: In this study, a strategy of constructing hydrogel microspheres through microencapsulation was proposed to deliver living probiotics to intestinal inflammatory areas. The microspheres showed high encapsulation efficiency and responsive release. The encapsulated probiotics exhibited high viability, nontoxicity, and favorable biodegradability, promising their potential applications in targeted therapy for inflammatory bowel disease.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Yeping Song, Yi Zhu, Qinghua Wang, Xin Chen, Yu Chen, Guohao Han, Weipeng Lu, Yanchuan Guo
Summary: The advantages of an ideal hemostasis material for emergency rescue are significant in mitigating patient distress and minimizing threat to life. However, obtaining a single material with desirable properties such as safety, antibacterial activity, high efficiency, sufficient mechanical strength, and cost-effectiveness remains challenging.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Materials Science, Biomaterials
Yi Zhu, Ling Lin, Yuntao Xie, Qinghua Wang, Chenghong Gu, Yu Chen, Yeping Song, Guohao Han, Weipeng Lu, Yanchuan Guo
Summary: Inspired by mussel foot proteins, self-assembling confined PDA nanoparticles were used to construct an antibacterial hydrogel wound dressing. The dressing exhibited outstanding antibacterial activity against MRSA and potential applications in superbug-infected wound healing.
BIOMATERIALS SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Yu Chen, Weipeng Lu, Yanchuan Guo, Yuntao Xie, Yi Zhu, Yeping Song
Summary: Combining ROS-scavenging and antibacterial activities, multifunctional gelatin/chitosan composite microspheres effectively alleviate oxidative stress and bacterial invasion in chronic wounds. The gelatin/chitosan scaffold with good biocompatibility promotes cell proliferation.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Physical
Yi Zhu, Ling Lin, Yu Chen, Yeping Song, Weipeng Lu, Yanchuan Guo
Article
Chemistry, Multidisciplinary
Yi Zhu, Weipeng Lu, Yanchuan Guo, Yu Chen, Yuxiao Wu, Haojun Lu