7-epi-Clusianone, a Multi-Targeting Natural Product with Potential Chemotherapeutic, Immune-Modulating, and Anti-Angiogenic Properties

A multi-targeting natural compound with growth inhibitory and anti-angiogenic properties re-sensitizes chemotherapy resistant cancer

(2019) Wesley F. Taylor et al.   PLoS One

Nicotinamide Augments the Anti-Inflammatory Properties of Resveratrol through PARP1 Activation

(2019) Maria Yanez et al.   Scientific Reports

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Modulation of Inflammatory Response to Implanted Biomaterials Using Natural Compounds

(2018) Maria Yanez et al.   CURRENT PHARMACEUTICAL DESIGN

Compound K Induces Endoplasmic Reticulum Stress and Apoptosis in Human Liver Cancer Cells by Regulating STAT3

(2018) Xuan Zhang et al.   MOLECULES

In vivo schistosomicidal activity of 7-epiclusianone and its quantification in the plasma of healthy and Schistosoma mansoni infected mice using UPLC-MS/MS

(2018) Aline Pereira Castro et al.   PHYTOMEDICINE

Current landscape and future of dual anti-CTLA4 and PD-1/PD-L1 blockade immunotherapy in cancer; lessons learned from clinical trials with melanoma and non-small cell lung cancer (NSCLC)

(2018) Young Kwang Chae et al.   Journal for ImmunoTherapy of Cancer

The role of the JAK/STAT signal pathway in rheumatoid arthritis

(2018) Charles J. Malemud   Therapeutic Advances in Musculoskeletal Disease

Cost Effectiveness of Chimeric Antigen Receptor T-Cell Therapy in Relapsed or Refractory Pediatric B-Cell Acute Lymphoblastic Leukemia

(2018) John K. Lin et al.   JOURNAL OF CLINICAL ONCOLOGY

Cytokine release syndrome: grading, modeling, and new therapy

(2018) Delong Liu et al.   Journal of Hematology & Oncology

Cytokines in clinical cancer immunotherapy

(2018) Pedro Berraondo et al.   BRITISH JOURNAL OF CANCER

Monoclonal antibodies in cancer immunotherapy

(2018) Ilgin Kimiz-Gebologlu et al.   MOLECULAR BIOLOGY REPORTS

Dendritic Cell Cancer Therapy: Vaccinating the Right Patient at the Right Time

(2018) Wouter W. van Willigen et al.   Frontiers in Immunology

The next generation of immunotherapy: keeping lung cancer in check

(2017) Ashwin Somasundaram et al.   Journal of Hematology & Oncology

Antibacterial Activity of 7-Epiclusianone and Its Novel Copper Metal Complex on Streptococcus spp. Isolated from Bovine Mastitis and Their Cytotoxicity in MAC-T Cells

(2017) Mariana de Barros et al.   MOLECULES

Wound Healing Potential of Chlorogenic Acid and Myricetin-3-O-β-Rhamnoside Isolated from Parrotia persica

(2017) Sara Moghadam et al.   MOLECULES

Current Challenges in Cancer Treatment

(2016) Jon Zugazagoitia et al.   CLINICAL THERAPEUTICS

Angiogenesis inhibitors as therapeutic agents in cancer: Challenges and future directions

(2016) Zhexuan Lin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Research review on the pharmacological effects of astragaloside IV

(2016) Lei Li et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Research Advances in the Intervention of Inflammation and Cancer by Active Ingredients of Traditional Chinese Medicine

(2016) Yinghong Huang et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Emodin Inhibits Breast Cancer Growth by Blocking the Tumor-Promoting Feedforward Loop between Cancer Cells and Macrophages

(2016) S. Iwanowycz et al.   MOLECULAR CANCER THERAPEUTICS

Driving CAR T-cells forward

(2016) Hollie J. Jackson et al.   Nature Reviews Clinical Oncology

Tumor-associated macrophages as an emerging target against tumors: Creating a new path from bench to bedside

(2015) Masahisa Jinushi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Anticancer activity of 7-epiclusianone, a benzophenone from Garcinia brasiliensis, in glioblastoma

(2015) Leilane Sales et al.   BMC Complementary and Alternative Medicine

Anti-inflammatory potential of saponins derived from cultured wild ginseng roots in lipopolysaccharide-stimulated RAW 264.7 macrophages

(2015) YU GYEONG-JIN et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

7-Epiclusianone, a Benzophenone Extracted from Garcinia brasiliensis (Clusiaceae), Induces Cell Cycle Arrest in G1/S Transition in A549 Cells

(2015) Marisa Ionta et al.   MOLECULES

Anti-tumor effect of emodin on gynecological cancer cells

(2015) Yaoxian Wang et al.   CELLULAR ONCOLOGY

Asymmetric, Stereodivergent Synthesis of (−)-Clusianone Utilizing a Biomimetic Cationic Cyclization

(2014) Jonathan H. Boyce et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Clusianone, a naturally occurring nemorosone regioisomer, uncouples rat liver mitochondria and induces HepG2 cell death

(2014) Felippe H.Z. Reis et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Curcumin in Combined Cancer Therapy

(2014) Koraljka Troselj et al.   CURRENT PHARMACEUTICAL DESIGN

Cancer wars: natural products strike back

(2014) Christine Basmadjian et al.   Frontiers in Chemistry

Strategies to Direct Angiogenesis within Scaffolds for Bone Tissue Engineering

(2013) Greg M. Harris et al.   CURRENT PHARMACEUTICAL DESIGN

Comparison of the cytotoxic effects of enantiopure PPAPs, including nemorosone and clusianone

(2012) Nigel S. Simpkins et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Antinociceptive and anti-inflammatory properties of 7-epiclusianone, a prenylated benzophenone from Garcinia brasiliensis

(2011) Flávia V. Santa-Cecília et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Antiproliferative effect of benzophenones and their influence on cathepsin activity

(2009) Ramiro Mendonça Murata et al.   PHYTOTHERAPY RESEARCH

Antimicrobial activity of Rheedia brasiliensis and 7-epiclusianone against Streptococcus mutans

(2008) L.S.B. Almeida et al.   PHYTOMEDICINE