Recognition of the gluconeogenic enzyme, Pck1, via the Gid4 E3 ligase: An in silico perspective

N-degron and C-degron pathways of protein degradation

(2019) Alexander Varshavsky   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpression of PCK1 Gene Antagonizes Hepatocellular Carcinoma Through the Activation of Gluconeogenesis and Suppression of Glycolysis Pathways

(2018) Yufu Tang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Understanding the Pro/N-end rule pathway

(2018) David A. Dougan et al.   Nature Chemical Biology

Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway

(2018) Cheng Dong et al.   Nature Chemical Biology

HPEPDOCK: a web server for blind peptide–protein docking based on a hierarchical algorithm

(2018) Pei Zhou et al.   NUCLEIC ACIDS RESEARCH

Novel Guanosine Derivatives as Anti-HCV NS5b polymerase: A QSAR and Molecular Docking Study

(2018) Abdo A Elfiky   Medicinal Chemistry

Applications of computer-aided approaches in the development of hepatitis C antiviral agents

(2017) Aravindhan Ganesan et al.   Expert Opinion on Drug Discovery

Molecular modeling and docking revealed superiority of IDX-184 as HCV polymerase inhibitor

(2017) Abdo A Elfiky et al.   Future Virology

Zika virus: novel guanosine derivatives revealed strong binding and possible inhibition of the polymerase

(2017) Abdo A Elfiky   Future Virology

Molecular dynamics simulation revealed binding of nucleotide inhibitors to ZIKV polymerase over 444 nanoseconds

(2017) Abdo A. Elfiky et al.   JOURNAL OF MEDICAL VIROLOGY

Novel homozygous PCK1 mutation causing cytosolic phosphoenolpyruvate carboxykinase deficiency presenting as childhood hypoglycemia, an abnormal pattern of urine metabolites and liver dysfunction

(2017) Päivi Vieira et al.   MOLECULAR GENETICS AND METABOLISM

An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes

(2017) Shun-Jia Chen et al.   SCIENCE

Efficient conformational ensemble generation of protein-bound peptides

(2017) Yumeng Yan et al.   Journal of Cheminformatics

Zika viral polymerase inhibition using anti-HCV drugs both in market and under clinical trials

(2016) Abdo A. Elfiky   JOURNAL OF MEDICAL VIROLOGY

Cytosolic phosphoenolpyruvate carboxykinase deficiency presenting with acute liver failure following gastroenteritis

(2016) Saikat Santra et al.   MOLECULAR GENETICS AND METABOLISM

PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth

(2015) Emily D. Montal et al.   MOLECULAR CELL

PLIP: fully automated protein–ligand interaction profiler

(2015) Sebastian Salentin et al.   NUCLEIC ACIDS RESEARCH

The QSAR and docking calculations of fullerene derivatives as HIV-1 protease inhibitors

(2015) Noha A. Saleh   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics

(2013) Linn Fagerberg et al.   MOLECULAR & CELLULAR PROTEOMICS

The N-End Rule Pathway

(2012) Takafumi Tasaki et al.   Annual Review of Biochemistry

Hexapeptide Functionality of Cellulose as NS3 Protease Inhibitors

(2012) Medhat Ibrahim et al.   Medicinal Chemistry

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

HHblits: lightning-fast iterative protein sequence searching by HMM-HMM alignment

(2011) Michael Remmert et al.   NATURE METHODS

The N-end rule pathway and regulation by proteolysis

(2011) Alexander Varshavsky   PROTEIN SCIENCE