Molecular dynamics simulation revealed binding of nucleotide inhibitors to ZIKV polymerase over 444 nanoseconds

Applications of computer-aided approaches in the development of hepatitis C antiviral agents

(2017) Aravindhan Ganesan et al.   Expert Opinion on Drug Discovery

Molecular modeling and docking revealed superiority of IDX-184 as HCV polymerase inhibitor

(2017) Abdo A Elfiky et al.   Future Virology

Quantitative structure-activity relationship and molecular docking revealed a potency of anti-hepatitis C virus drugs against human corona viruses

(2017) Abdo A. Elfiky et al.   JOURNAL OF MEDICAL VIROLOGY

Molecular detection of Zika virus in blood and RNA load determination during the French Polynesian outbreak

(2017) Didier Musso et al.   JOURNAL OF MEDICAL VIROLOGY

A structural view of the RNA-dependent RNA polymerases from the Flavivirus genus

(2017) Guoliang Lu et al.   VIRUS RESEARCH

The structure of Zika virus NS5 reveals a conserved domain conformation

(2017) Boxiao Wang et al.   Nature Communications

Crystal structure of full-lengthZika virusNS5 protein reveals a conformation similar toJapanese encephalitis virusNS5

(2017) Anup K. Upadhyay et al.   Acta Crystallographica Section F-Structural Biology Communications

Water Determines the Structure and Dynamics of Proteins

(2016) Marie-Claire Bellissent-Funel et al.   CHEMICAL REVIEWS

Zika virus outbreak and the case for building effective and sustainable rapid diagnostics laboratory capacity globally

(2016) Alimuddin Zumla et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Potential use of saliva samples to diagnose Zika virus infection

(2016) L.B. Tauro et al.   JOURNAL OF MEDICAL VIROLOGY

Zika viral polymerase inhibition using anti-HCV drugs both in market and under clinical trials

(2016) Abdo A. Elfiky   JOURNAL OF MEDICAL VIROLOGY

IDX-184 is a superior HCV direct-acting antiviral drug: a QSAR study

(2016) Abdo A. Elfiky et al.   MEDICINAL CHEMISTRY RESEARCH

Zika Virus Associated with Microcephaly

(2016) Jernej Mlakar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Theoretical Study on Modified Boceprevir Compounds as NS3 Protease Inhibitors

(2015) Noha A. Saleh et al.   Journal of Computational and Theoretical Nanoscience

2′-Methylguanosine Prodrug (IDX-184), Phosphoramidate Prodrug (Sofosbuvir), Diisobutyryl Prodrug (R7128) Are Better Than Their Parent Nucleotides and Ribavirin in Hepatitis C Virus Inhibition: A Molecular Modeling Study

(2015) Abdo A. Elfiky et al.   Journal of Computational and Theoretical Nanoscience

RNA-Dependent RNA Polymerases of Picornaviruses: From the Structure to Regulatory Mechanisms

(2015) Cristina Ferrer-Orta et al.   Viruses-Basel

Daclatasvir plus sofosbuvir for HCV infection: An oral combination therapy with high antiviral efficacy

(2014) Tarik Asselah   JOURNAL OF HEPATOLOGY

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

Sofosbuvir for the treatment of hepatitis C virus

(2013) Tarik Asselah   EXPERT OPINION ON PHARMACOTHERAPY

The Electronic and Quantitative Structure Activity Relationship Properties of Modified Telaprevir Compounds as HCV NS3 Protease Inhibitors

(2013) Noha A. Saleh et al.   Journal of Computational and Theoretical Nanoscience

Molecular Modeling Comparison of the Performance of NS5b Polymerase Inhibitor (PSI-7977) on Prevalent HCV Genotypes

(2013) Abdo A. Elfiky et al.   PROTEIN JOURNAL

Structural properties of metal-free apometallothioneins

(2012) Kelly L. Summers et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hexapeptide Functionality of Cellulose as NS3 Protease Inhibitors

(2012) Medhat Ibrahim et al.   Medicinal Chemistry

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Solvent accessible surface area approximations for rapid and accurate protein structure prediction

(2009) Elizabeth Durham et al.   JOURNAL OF MOLECULAR MODELING

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

Zika Virus Outbreak on Yap Island, Federated States of Micronesia

(2009) Mark R. Duffy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structural and electronic properties of new fullerene derivatives and their possible application as HIV-1 protease inhibitors

(2009) Medhat Ibrahim et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY