Single-cell analysis of RORα tracer mouse lung reveals ILC progenitors and effector ILC2 subsets

An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials

(2019) Wei Xu et al.   IMMUNITY

Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow

(2019) Jennifer A. Walker et al.   IMMUNITY

Tissue-Resident Group 2 Innate Lymphoid Cells Differentiate by Layered Ontogeny and In Situ Perinatal Priming

(2019) Christoph Schneider et al.   IMMUNITY

GITR cosignal in ILC2s controls allergic lung inflammation

(2018) Hiroyuki Nagashima et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense

(2018) Yuefeng Huang et al.   SCIENCE

Mysterious ILC2 tissue adaptation

(2018) Jinfang Zhu   NATURE IMMUNOLOGY

Tissue signals imprint ILC2 identity with anticipatory function

(2018) Roberto R. Ricardo-Gonzalez et al.   NATURE IMMUNOLOGY

Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency

(2017) Yannick Simoni et al.   IMMUNITY

Group 2 innate lymphoid cell activation in the neonatal lung drives type 2 immunity and allergen sensitization

(2017) Catherine A. Steer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

ILC2-modulated T cell–to-MDSC balance is associated with bladder cancer recurrence

(2017) Mathieu F. Chevalier et al.   JOURNAL OF CLINICAL INVESTIGATION

Immune checkpoints on innate lymphoid cells

(2017) Laura Chiossone et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PD-1 regulates KLRG1+group 2 innate lymphoid cells

(2017) Samuel Taylor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Development and differentiation of early innate lymphoid progenitors

(2017) Christelle Harly et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells

(2017) Simon Rauber et al.   NATURE MEDICINE

Alternative activation generates IL-10 producing type 2 innate lymphoid cells

(2017) Corey R. Seehus et al.   Nature Communications

Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis

(2017) Sara Trabanelli et al.   Nature Communications

First-Breath-Induced Type 2 Pathways Shape the Lung Immune Environment

(2017) Simona Saluzzo et al.   Cell Reports

The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome

(2016) Meital Gury-BenAri et al.   CELL

Perinatal Activation of the Interleukin-33 Pathway Promotes Type 2 Immunity in the Developing Lung

(2016) Ismé M. de Kleer et al.   IMMUNITY

Allergen-Experienced Group 2 Innate Lymphoid Cells Acquire Memory-like Properties and Enhance Allergic Lung Inflammation

(2016) Itziar Martinez-Gonzalez et al.   IMMUNITY

Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia

(2016) Steven G. Smith et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Synergistically increased ILC2 and Th9 cells in lung tissue jointly promote the pathological process of asthma in mice

(2016) XINYU YING et al.   Molecular Medicine Reports

IL-4-producing ILC2s are required for the differentiation of TH2 cells following Heligmosomoides polygyrus infection

(2016) V S Pelly et al.   Mucosal Immunology

Single-cell RNA-seq identifies a PD-1hi ILC progenitor and defines its development pathway

(2016) Yong Yu et al.   NATURE

The heterogeneity of human CD127+ innate lymphoid cells revealed by single-cell RNA sequencing

(2016) Åsa K Björklund et al.   NATURE IMMUNOLOGY

Single-cell analysis defines the divergence between the innate lymphoid cell lineage and lymphoid tissue–inducer cell lineage

(2016) Isabel E Ishizuka et al.   NATURE IMMUNOLOGY

A tissue checkpoint regulates type 2 immunity

(2016) Steven J Van Dyken et al.   NATURE IMMUNOLOGY

Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation

(2016) Laurel A Monticelli et al.   NATURE IMMUNOLOGY

Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis

(2016) Christoph S N Klose et al.   NATURE IMMUNOLOGY

Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs

(2016) Jonathan S Silver et al.   NATURE IMMUNOLOGY

Common-Lymphoid-Progenitor-Independent Pathways of Innate and T Lymphocyte Development

(2016) Maryam Ghaedi et al.   Cell Reports

Transcriptional Regulation of Innate and Adaptive Lymphocyte Lineages

(2015) Maria Elena De Obaldia et al.   Annual Review of Immunology

Defining cell types and states with single-cell genomics

(2015) Cole Trapnell   GENOME RESEARCH

ICOS:ICOS-Ligand Interaction Is Required for Type 2 Innate Lymphoid Cell Function, Homeostasis, and Induction of Airway Hyperreactivity

(2015) Hadi Maazi et al.   IMMUNITY

Interleukin-33 and Interferon-γ Counter-Regulate Group 2 Innate Lymphoid Cell Activation during Immune Perturbation

(2015) Ari B. Molofsky et al.   IMMUNITY

IL-18 Acts in Synergy with IL-7 To Promote Ex Vivo Expansion of T Lymphoid Progenitor Cells

(2015) Siva K. Gandhapudi et al.   JOURNAL OF IMMUNOLOGY

The biology of innate lymphoid cells

(2015) David Artis et al.   NATURE

Runx3 specifies lineage commitment of innate lymphoid cells

(2015) Takashi Ebihara et al.   NATURE IMMUNOLOGY

TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow

(2015) Qi Yang et al.   NATURE IMMUNOLOGY

The development of innate lymphoid cells requires TOX-dependent generation of a common innate lymphoid cell progenitor

(2015) Corey R Seehus et al.   NATURE IMMUNOLOGY

Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets

(2015) Michelle L Robinette et al.   NATURE IMMUNOLOGY

IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin–EGFR interactions

(2015) Laurel A. Monticelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tissue residency of innate lymphoid cells in lymphoid and nonlymphoid organs

(2015) G. Gasteiger et al.   SCIENCE

Innate lymphoid cells: A new paradigm in immunology

(2015) G. Eberl et al.   SCIENCE

Lung ILC2s link innate and adaptive responses in allergic inflammation

(2015) Itziar Martinez-Gonzalez et al.   TRENDS IN IMMUNOLOGY

Differentiation of Type 1 ILCs from a Common Progenitor to All Helper-like Innate Lymphoid Cell Lineages

(2014) Christoph S.N. Klose et al.   CELL

Development, Differentiation, and Diversity of Innate Lymphoid Cells

(2014) Andreas Diefenbach et al.   IMMUNITY

The Transcription Factor GATA3 Is Critical for the Development of All IL-7Rα-Expressing Innate Lymphoid Cells

(2014) Ryoji Yagi et al.   IMMUNITY

GATA-3 Function in Innate and Adaptive Immunity

(2014) Irma Tindemans et al.   IMMUNITY

Clock gene Per1 regulates the production of CCL2 and interleukin-6 through p38, JNK1 and NF-κB activation in spinal astrocytes

(2014) Tatsuhiko Sugimoto et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

A committed precursor to innate lymphoid cells

(2014) Michael G. Constantinides et al.   NATURE

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

IL-25-responsive, lineage-negative KLRG1hi cells are multipotential ‘inflammatory’ type 2 innate lymphoid cells

(2014) Yuefeng Huang et al.   NATURE IMMUNOLOGY

Type 2 innate lymphoid cells constitutively express arginase-I in the naïve and inflamed lung

(2013) Jennifer K. Bando et al.   JOURNAL OF LEUKOCYTE BIOLOGY

IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis

(2013) E. Hams et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Geniculocortical Input Drives Genetic Distinctions Between Primary and Higher-Order Visual Areas

(2013) S.-J. Chou et al.   SCIENCE

The Transcription Factor GATA3 Is Essential for the Function of Human Type 2 Innate Lymphoid Cells

(2012) Jenny Mjösberg et al.   IMMUNITY

The Transcription Factor GATA-3 Controls Cell Fate and Maintenance of Type 2 Innate Lymphoid Cells

(2012) Thomas Hoyler et al.   IMMUNITY

Lung Natural Helper Cells Are a Critical Source of Th2 Cell-Type Cytokines in Protease Allergen-Induced Airway Inflammation

(2012) Timotheus Y.F. Halim et al.   IMMUNITY

Retinoic-Acid-Receptor-Related Orphan Nuclear Receptor Alpha Is Required for Natural Helper Cell Development and Allergic Inflammation

(2012) Timotheus Y.F. Halim et al.   IMMUNITY

Transcription factor RORα is critical for nuocyte development

(2012) See Heng Wong et al.   NATURE IMMUNOLOGY

Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors

(2011) Kai Schledzewski et al.   JOURNAL OF CLINICAL INVESTIGATION

Interferon Regulatory Factor 2 Binding Protein 2 Is a New NFAT1 Partner and Represses Its Transcriptional Activity

(2011) F. R. G. Carneiro et al.   MOLECULAR AND CELLULAR BIOLOGY

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

(2011) Mourad Matmati et al.   NATURE GENETICS

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

(2011) Laurel A Monticelli et al.   NATURE IMMUNOLOGY

An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation

(2011) Christoph Wilhelm et al.   NATURE IMMUNOLOGY

IRF2BP2 is a skeletal and cardiac muscle-enriched ischemia-inducible activator of VEGFA expression

(2010) Allen C. T. Teng et al.   FASEB JOURNAL

Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development

(2009) M. A. Inlay et al.   GENES & DEVELOPMENT

The ligand-binding profile of HARE: hyaluronan and chondroitin sulfates A, C, and D bind to overlapping sites distinct from the sites for heparin, acetylated low-density lipoprotein, dermatan sulfate, and CS-E

(2008) E. N. Harris et al.   GLYCOBIOLOGY