Novel relaxant effects of RPL554 on guinea pig tracheal smooth muscle contractility

Aberrant DNA Methylation of Phosphodiestarase 4D Alters Airway Smooth Muscle Cell Phenotypes

(2016) Amanda H. Y. Lin et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Concise Guide to PHARMACOLOGY 2015/16: Other ion channels

(2015) Stephen PH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors

(2015) Stephen PH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2015/16: Voltage-gated ion channels

(2015) Stephen PH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2015/16: Enzymes

(2015) Stephen PH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Experimental design and analysis and their reporting: new guidance for publication in BJP

(2015) Michael J Curtis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP

(2015) John C McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Tiotropium and olodaterol fixed-dose combinationversusmono-components in COPD (GOLD 2–4)

(2015) Roland Buhl et al.   EUROPEAN RESPIRATORY JOURNAL

The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands

(2015) Christopher Southan et al.   NUCLEIC ACIDS RESEARCH

Pharmacological characterization of the interaction between the dual phosphodiesterase (PDE) 3/4 inhibitor RPL554 and glycopyrronium on human isolated bronchi and small airways

(2015) Luigino Calzetta et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Emergency treatment of status asthmaticus with enoximone

(2014) J. Beute   BRITISH JOURNAL OF ANAESTHESIA

Current and novel bronchodilators in respiratory disease

(2013) Domenico Spina   CURRENT OPINION IN PULMONARY MEDICINE

A new class of bronchodilator improves lung function in COPD: a trial with GSK961081

(2013) Pascal L.M.L. Wielders et al.   EUROPEAN RESPIRATORY JOURNAL

Transcriptome sequencing (RNA-Seq) of human endobronchial biopsies: asthmaversuscontrols

(2013) Ching Yong Yick et al.   EUROPEAN RESPIRATORY JOURNAL

Bronchorelaxation of the human bronchi by CFTR activators

(2013) Caroline Norez et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Combination bronchodilator therapy in the management of chronic obstructive pulmonary disease

(2013) Donald P Tashkin et al.   RESPIRATORY RESEARCH

Efficacy and safety of RPL554, a dual PDE3 and PDE4 inhibitor, in healthy volunteers and in patients with asthma or chronic obstructive pulmonary disease: findings from four clinical trials

(2013) Lui G Franciosi et al.   Lancet Respiratory Medicine

Therapeutic Potential of ASP3258, a Selective Phosphodiesterase 4 Inhibitor, on Chronic Eosinophilic Airway Inflammation

(2012) Miki Kobayashi et al.   PHARMACOLOGY

Preclinical efficacy of THRX-200495, a dual pharmacology muscarinic receptor antagonist and β2-adrenoceptor agonist (MABA)

(2012) Alexander McNamara et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

β2-Agonist Induced cAMP Is Decreased in Asthmatic Airway Smooth Muscle Due to Increased PDE4D

(2011) Thomas Trian et al.   PLoS One

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials

(2009) Leonardo M Fabbri et al.   LANCET

A quantitative study to assess synergistic interactions between urotensin II and angiotensin II

(2008) Neil S. Lamarre et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A Major Functional Role for Phosphodiesterase 4D5 in Human Airway Smooth Muscle Cells

(2007) Charlotte K. Billington et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Supra-additive effects of tramadol and acetaminophen in a human pain model☆

(2007) Jörg Filitz et al.   PAIN