Acetate and Butyrate Improve β-cell Metabolism and Mitochondrial Respiration under Oxidative Stress

Interactions between Host PPARs and Gut Microbiota in Health and Disease

(2019) Arif Hasan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial fusion and maintenance of mitochondrial homeostasis in diabetic retinopathy

(2019) Arul J. Duraisamy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitofusin 2 Participates in Mitophagy and Mitochondrial Fusion Against Angiotensin II-Induced Cardiomyocyte Injury

(2019) Wenjun Xiong et al.   Frontiers in Physiology

The Short-Chain Fatty Acid Acetate in Body Weight Control and Insulin Sensitivity

(2019) Hernández et al.   Nutrients

Circulating but not faecal short-chain fatty acids are related to insulin sensitivity, lipolysis and GLP-1 concentrations in humans

(2019) Mattea Müller et al.   Scientific Reports

Impact of Dietary Fiber Consumption on Insulin Resistance and the Prevention of Type 2 Diabetes

(2018) Martin O Weickert et al.   JOURNAL OF NUTRITION

The prebiotic inulin improves substrate metabolism and promotes short-chain fatty acid production in overweight to obese men

(2018) Christina M. van der Beek et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Short chain fatty acids stimulate insulin secretion and reduce apoptosis in mouse and human islets in vitro: role of FFAR2

(2018) A. Pingitore et al.   DIABETES OBESITY & METABOLISM

Single-cell gene expression analysis reveals β-cell dysfunction and deficit mechanisms in type 2 diabetes

(2018) Lichun Ma et al.   BMC BIOINFORMATICS

Butyrate stimulates adipose lipolysis and mitochondrial oxidative phosphorylation through histone hyperacetylation-associated β3 -adrenergic receptor activation in high-fat diet-induced obese mice

(2017) Yimin Jia et al.   EXPERIMENTAL PHYSIOLOGY

Stimulation of vascularization of a subcutaneous scaffold applicable for pancreatic islet-transplantation enhances immediate post-transplant islet graft function but not long-term normoglycemia

(2017) Alexandra M. Smink et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Laminin and collagen IV inclusion in immunoisolating microcapsules reduces cytokine-mediated cell death in human pancreatic islets

(2017) L. Alberto Llacua et al.   Journal of Tissue Engineering and Regenerative Medicine

Microbiota-activated PPAR-γ signaling inhibits dysbiotic Enterobacteriaceae expansion

(2017) Mariana X. Byndloss et al.   SCIENCE

The Crosstalk between the Gut Microbiota and Mitochondria during Exercise

(2017) Allison Clark et al.   Frontiers in Physiology

A proliferative probiotic Bifidobacterium strain in the gut ameliorates progression of metabolic disorders via microbiota modulation and acetate elevation

(2017) Ryo Aoki et al.   Scientific Reports

Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight/obese men: a randomized crossover trial

(2017) Emanuel E. Canfora et al.   Scientific Reports

Challenges and issues with streptozotocin-induced diabetes – A clinically relevant animal model to understand the diabetes pathogenesis and evaluate therapeutics

(2016) Sameer N. Goyal et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Distal, not proximal, colonic acetate infusions promote fat oxidation and improve metabolic markers in overweight/obese men

(2016) C. M. van der Beek et al.   CLINICAL SCIENCE

The diet-derived short chain fatty acid propionate improves beta-cell function in humans and stimulates insulin secretion from human islets in vitro

(2016) Attilio Pingitore et al.   DIABETES OBESITY & METABOLISM

Short-Chain Fatty Acid Acetate Stimulates Adipogenesis and Mitochondrial Biogenesis via GPR43 in Brown Adipocytes

(2016) Jiamiao Hu et al.   ENDOCRINOLOGY

Recombinant Reg3β protein protects against streptozotocin-induced β-cell damage and diabetes

(2016) Chen Luo et al.   Scientific Reports

Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival

(2016) Stephanie R. Villa et al.   Scientific Reports

Short-chain fatty acids in control of body weight and insulin sensitivity

(2015) Emanuel E. Canfora et al.   Nature Reviews Endocrinology

Islet Oxygen Consumption Rate (OCR) Dose Predicts Insulin Independence in Clinical Islet Autotransplantation

(2015) Klearchos K. Papas et al.   PLoS One

FFAR3 modulates insulin secretion and global gene expression in mouse islets

(2015) Medha Priyadarshini et al.   Islets

Reconfigurable microfluidic hanging drop network for multi-tissue interaction and analysis

(2014) Olivier Frey et al.   Nature Communications

Effect of eating vegetables before carbohydrates on glucose excursions in patients with type 2 diabetes

(2013) Saeko Imai et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43

(2013) Ikuo Kimura et al.   Nature Communications

The Microbe-Derived Short Chain Fatty Acid Butyrate Targets miRNA-Dependent p21 Gene Expression in Human Colon Cancer

(2011) Shien Hu et al.   PLoS One

Mitochondrial fatty acid oxidation and oxidative stress: Lack of reverse electron transfer-associated production of reactive oxygen species

(2010) Peter Schönfeld et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Butyrate and other short-chain fatty acids as modulators of immunity: what relevance for health?

(2010) Kees Meijer et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids

(2010) Mohamed S. Zaibi et al.   FEBS LETTERS

Lack of TXNIP Protects Against Mitochondria-Mediated Apoptosis but Not Against Fatty Acid-Induced ER Stress-Mediated  -Cell Death

(2009) J. Chen et al.   DIABETES

Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice

(2009) Z. Gao et al.   DIABETES

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

Pancreatic Beta-Cell Purification by Altering FAD and NAD(P)H Metabolism

(2008) M. J. Smelt et al.   Experimental Diabetes Research