Article
Biochemistry & Molecular Biology
Raziel Arturo Jimenez-Nava, Luis Gerardo Zepeda-Vallejo, Fortunata Santoyo-Tepole, Griselda Ma. Chavez-Camarillo, Eliseo Cristiani-Urbina
Summary: In this study, we successfully isolated and identified a yellow fluorescent compound excreted by the yeast Hyphopichia wangnamkhiaoensis as riboflavin, using RP-HPLC-DAD, H-1 NMR, and UV-Vis spectroscopy. The compound exhibited similar absorption wavelengths as flavins and had maximum excitation and emission wavelengths identical to riboflavin.
Article
Chemistry, Analytical
Siddheshwar Kisan Chauthe, Padmaja Sidduri, Manjunatha Reddy, Ramesh Sistla, Vijay Byri, Murali Dhararao Uttaravalli, Murali Botlagunta, Hemantha Kumar, Anuradha Gupta, Arun Kumar Gupta, Lakshmikant Bajpai, Muralidhararao Bagadi, Arvind Mathur
Summary: Due to drug resistance and tolerability, it is important to discover new compounds for HIV treatment. In this study, an intermediate compound SCMTDDA was synthesized and a simple and efficient HPLC method was developed to separate its interconvertible rotamers. The separation was further validated using NMR and DFT calculations.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2022)
Article
Chemistry, Analytical
Livia Oliveira Alves Ferreira, Szilard Molnar, Felipe Terra Martins, Pal Perjesi, Luiz Henrique Keng Queiroz, Caridad Noda-Perez
Summary: The study on symmetrical halogenated bischalcones (SHBCs) and their Michael addition reaction with reduced glutathione (GSH) revealed that the formation of adducts did not directly correlate with their cytotoxic effects on cancer cells.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Applied
Nerilson M. Lima, Teresinha J. A. S. Andrade, Dulce Helena S. Silva
Summary: The study identified sixteen compounds from Inga edulis leaves extract using dereplication strategy, including triterpenes, flavonoids, phenolic acids, and anthocyanins. The species showed strong antioxidant potential with phenolic compounds as major constituents. The techniques used in this study provided effective strategies for the early detection of active natural products from plant extracts.
NATURAL PRODUCT RESEARCH
(2022)
Article
Food Science & Technology
Leila Bandian, Mohhammad Moghaddam, Massoumeh Bahreini, Effat Vatankhah
Summary: This study evaluated the antibacterial effects of e-polylysine and plant extracts on Pseudomonas aeruginosa and Pectobacterium carotovorum. Results showed that e-polylysine and certain plant extracts could deform bacterial membranes, with varying minimum inhibitory concentration values.
Article
Pharmacology & Pharmacy
Marcin Janiaczyk, Anna Jelinska, Aneta Wozniak-Braszak, Pawel Bilski, Maria Popielarz-Brzezinska, Magdalena Wachowiak, Mikolaj Baranowski, Szymon Tomczak, Magdalena Ogrodowczyk
Summary: The ionizing radiation stability of the nonsteroidal anti-inflammatory drugs diclofenac and aceclofenac was investigated, and it was found that they exhibit high radiation stability within a certain dose range, making them suitable for sterilization. The study also observed the influence of radiation on molecular dynamics and structure.
Article
Environmental Sciences
Xiaolei Dong, Fanghao Yang, Xiaohui Xu, Feng Zhu, Guoxiang Liu, Fenghua Xu, Guang Chen, Can Cao, Lei Teng, Xiaoxia Li, Lin Wang, Bing Li
Summary: C-phycocyanin (C-PC) has been found to possess antioxidant properties and can protect GC-1 spg cells from oxidative stress damage induced by H2O2. This protective effect may be attributed to the antioxidation ability, reduction of ROS production, and regulation of cell necrosis signaling pathways.
ENVIRONMENTAL TOXICOLOGY
(2022)
Review
Cell Biology
Christoph Seger, Sonja Sturm
Summary: NMR spectroscopy is essential for determining the structural information of analytes from natural sources in liquid state. While mass spectrometry can differentiate and group biomarkers, the structural characterization often requires the use of NMR spectroscopy.
Article
Food Science & Technology
Xia Wu, Ying Liu, Jieqing Guo, Juanxia Wang, Meizhen Li, Youzhen Tan, Qifan Zheng, Yifan Feng
Summary: This study used advanced techniques to identify 43 elements and 29 metabolites in Pu-erh raw tea, providing a feasible and rapid method for distinguishing Pu-erh tea from different geographical origins.
JOURNAL OF FOOD SCIENCE
(2021)
Article
Food Science & Technology
Andrea Aleixandre, Mauro Gisbert, Jorge Sineiro, Ramon Moreira, Cristina M. Rosell
Summary: Seaweed extracts have strong antidiabetic properties, and ultrasound-assisted extraction and resin purification can enhance the inhibitory effects of the extracts on starch digestive enzymes, with better inhibition effect when preincubated with enzymes.
JOURNAL OF FOOD SCIENCE
(2022)
Article
Agricultural Engineering
Birgitta Narindri Rara Winayu, Hsin-Ta Hsueh, Hsin Chu
Summary: In this study, Thermosynechococcus sp. CL-1 (TCL-1) was successfully cultivated in a photobioreactor, resulting in high CO2 fixation rate and lipid content. TCL-1 also potentially produced abundant phycocyanin, dominated by C-phycocyanin, and the protective effect of 36% glucose solvent on phycocyanin was revealed.
BIORESOURCE TECHNOLOGY
(2022)
Article
Biochemical Research Methods
Joan Bergman, Lainey Harvill, Shawna Hawkins, Kurt Sladky, Sherry Cox
Summary: A simple high-performance liquid chromatography method for the determination of ceftazidime in plasma has been successfully developed. The method showed good precision and accuracy, with intra- and inter-assay variability for ceftazidime <12% and average recovery of 89%. This method could be applied to analyze small volume samples in clinical or research settings.
BIOMEDICAL CHROMATOGRAPHY
(2021)
Article
Biotechnology & Applied Microbiology
Julie Billy, Jeremy Pruvost, Olivier Lepine, Delphine Drouin, Olivier Goncalves
Summary: This study developed a reliable method to quantify C-phycocyanin, specifically for Aphanizomenon flos-aquae (AFA) samples. The commonly used spectrophotometric method tends to overestimate the amount of C-phycocyanin, so the aim was to adapt the method for AFA and account for variation in C-phycocyanin between different cyanobacteria species. High performance liquid chromatography (HPLC) was used as a reference method, and a new set of spectrophotometric quantification equations was obtained. This method has the potential to improve quantification methods for other types of phycocyanin, cyanobacteria, and compounds currently quantified by spectrophotometry.
JOURNAL OF APPLIED PHYCOLOGY
(2023)
Article
Chemistry, Analytical
Muhammad Sohail Anwar, Abad Khan, Ismail Khan, Saeed Ahmad Khan, Lateef Ahmad, Waqar Ahmad Kaleem, Ali Mahzari, Wafa Abdullah I. Al-Megrin, Ahmad Almatroudi, Khaled S. Allemailem, Fahim Ullah Khan
Summary: In this study, FTIR and HPLC were used for the identification and quantification of synthetic steroids adulterated in herbal products. The samples were extracted with methanol and quantified by HPLC using a mobile phase of methanol:water. The developed method proved to be simple, sensitive, and cost-effective for analyzing the studied steroids in dosage forms and body fluids.
MICROCHEMICAL JOURNAL
(2023)
Article
Fisheries
Hua Yang, Xueni Qiu, Yun Zhao, Yangfang Ye, Weiwei Song, Changkao Mu, Ronghua Li, Chunlin Wang
Summary: This study investigated the optimal anesthetic concentration for cuttlefish using NMR and HPLC analysis. They found that ethanol at 10-30 mL L-1 successfully anesthetized cuttlefish, with recovery observed after 60 minutes at 10 mL L-1 concentration. Cuttlefish also reached a sedative state below 5 mL L-1 ethanol, with a maximum exposure time of 270 minutes. The action of ethanol led to changes in neurotransmitter levels, with increased inhibitory neurotransmitters and decreased excitatory neurotransmitters observed.
Article
Biochemistry & Molecular Biology
S. Karthick Raja Namasivayam, L. Vigneshwaraprakash, K. Samrat, M. Kavisri, Meivelu Moovendhan, R. S. Arvind Bharani
Summary: Using natural and synthetic polymers as components, a core-shell nanocomposite was synthesized employing green science principles. The nanocomposite showed high stability and exhibited enhanced antibacterial activity against Pseudomonas aeruginosa. In addition, it demonstrated controlled and sustained drug release pattern and was found to be compatible with human keratinocytes.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2023)
Article
Environmental Sciences
M. Kavisri, Marykutty Abraham, Meivelu Moovendhan
Summary: This study focused on using phytoremediation technology from marine microalgae Dunaliella salina to remove fluoride ions from aqueous solution. The physical characteristics, functional groups, and surface microstructure of the microalgae were analyzed, and the removal of fluoride was optimized through various conditions and methods. The study showed that microalgae are a novel, low-cost, and effective bio-based method for the bioremediation of fluoride from water bodies and industrial wastewaters.
Article
Biochemistry & Molecular Biology
S. Karthick Raja Namasivayam, U. Karthika Pandian, Vani Chava, R. S. Arvind Bharani, M. Kavisri, Meivelu Moovendhan
Summary: In this study, the herbicidal activity of a chitosan nanocomposite containing fungal metabolites was investigated against the invasive water hyacinth. The synthesized nanocomposite showed significant herbicidal effects on the leaflets of water hyacinth, causing necrotic damage and functional changes. Ethyl acetate treatment demonstrated controlled release of the metabolites, while revealing no toxic effects on zebrafish embryonic development, indicating the biocompatibility of the nanocomposite.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Microbiology
Balaji Maddiboyina, Hari Krishna Vanamamalai, Harekrishna Roy, Ramaiah, Sivaraman Gandhi, M. Kavisri, Meivelu Moovendhan
Summary: Spirulina platensis is a blue-green, spiral- or bulb-shaped microalgae with high nutritional value. It has been used as a nutritional supplement for astronauts and has various pharmacological effects, such as antibacterial, anticancer, metalloprotective, immune-stimulating, and antioxidant activities.
JOURNAL OF BASIC MICROBIOLOGY
(2023)
Article
Energy & Fuels
S. Karthick Raja Namasivayam, Esther Haveela, K. Samra, R. S. Arvind Bharani, Sivaraj Sigamani, Ramachandran Srinivasan, M. Kavisri, Meivelu Moovendhan
Summary: The study investigated the enhanced cytotoxic effect of gold nanoparticle-loaded camptothecin on a breast cancer cell line. Camptothecin was isolated from Aspergillus niger biomass and loaded onto chemically synthesized gold nanoparticles, forming a nano-drug conjugate. The prepared nanoformulation showed significant anticancer activity against breast cancer cells.
BIOMASS CONVERSION AND BIOREFINERY
(2023)
Article
Biochemistry & Molecular Biology
Balaji Maddiboyina, Harekrishna Roy, Ramya Krishna Nakkala, Sivaraman Gandhi, M. Kavisri, Meivelu Moovendhan
Summary: Multidrug resistance in breast cancer and associated side effects of anticancer therapies are major obstacles in chemotherapy-based treatment. Biodegradable polymeric nano-based targeted drug delivery technologies have shown significant advantages in targeted local delivery with minimal off-target side effects. Therefore, there is a continuous need for the development of targeted nanomedicine systems for breast cancer treatment. This study aimed to develop poly (lactic-co-glycolic acid) nanoparticles loaded with raloxifene to improve oral bioavailability. The optimized formulation showed desirable particle size, polydispersity index, and drug entrapment efficiency, and demonstrated stability during storage.
CHEMICAL BIOLOGY & DRUG DESIGN
(2023)
Article
Microbiology
Mariadhas Valan Arasu, Ponnuswamy Vijayaraghavan, Naif Abdullah Al-Dhabi, Ki Choon Choi, Meivelu Moovendhan
Summary: The main objective of this study was to isolate T. gamsii RH4 strain from black gram rhizosphere and evaluate its growth-promoting and rot disease-protecting activities. The results showed that T. gamsii exhibited significant inhibition against wilt and rot disease and promoted the growth and yield of black gram. Therefore, this strain has the potential to improve biocontrol properties.
JOURNAL OF BASIC MICROBIOLOGY
(2023)
Review
Green & Sustainable Science & Technology
S. Karthick Raja Namasivayam, P. Prakash, Vishnupriya Babu, Eric Johnson Paul, R. S. Arvind Bharani, J. Aravind Kumar, M. Kavisri, Meivelu Moovendhan
Summary: This paper provides a comprehensive and accurate overview of nanocellulose acetate membrane technology in waste water treatment. The synthesis process of nanocellulose acetate membrane through electrospinning and its potential role in waste water remediation were discussed. Factors influencing the electrospinning process, efficacy testing methods and the role of water treatment process were described.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Environmental Sciences
M. Kavisri, Marykutty Abraham, S. Karthik Raja Namasivayam, J. Aravindkumar, D. Balaji, Ramamoorthy Sathishkumar, Sivaraj Sigamani, Ramachandran Srinivasan, Meivelu Moovendhan
Summary: The aim of this study was to investigate the efficiency, mechanism, and characterization of Chitosan biopolymers from cephalopods waste in removing cadmium. The extracted chitosan showed a high yield of 32% and contained high mineral, ash, and moisture content. Analysis using FT-IR revealed the presence of multiple active functional groups, while 1H NMR identified sugar signals in Chitosan. SEM analysis showed that Chitosan had a crystalline, rough surface with micropores, which played a key role in the adsorption process. Batch experiments indicated that pH, temperature, time, and dosage significantly influenced the Cd ion removal process, with the optimum conditions determined. Kinetics modeling showed that the Pseudo-second order model was more suitable for Cd removal. Chitosan's surface characteristics and functional groups were found to play a crucial role in the adsorption process, making it an environmentally friendly, cost-effective, and highly efficient sorbent for heavy metal removal in effluent treatment plants.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Review
Engineering, Environmental
S. Karthick Raja Namasivayam, Subramanian Srinivasan, Krishnappa Samrat, Bala Priyalakshmi, Ramkumar Dinesh Kumar, Arvind Bharani, Ramkumar Ganesh Kumar, M. Kavisri, Meivelu Moovendhan
Summary: This review provides an insight into the principles of nanotechnology for the formulation of plant-based rodenticides and how they can be developed to be superior to conventional rodent control programs. It discusses the selection of plant material, extraction of rodenticidal metabolites, and formulation of plant extracts as nanoparticles or other nanomaterials using green science or green technology principles. The review also emphasizes the importance of characterizing the nano-formulation, determining its efficacy, and assessing its stability and biocompatibility before practical application. Overall, this study highlights the potential of Nano Phyto rodenticides formulated by green nanotechnology for eco-friendly and effective rodent control.
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
(2023)
Article
Energy & Fuels
A. L. Francis, S. Karthick Raja Namasivayam, M. Kavisri, Meivelu Moovendhan
Summary: Metabolites derived from herbal plants have shown notable healing activity against various skin infection diseases. However, scientific validation is needed to determine the bioactive metabolites and their anti-microbial principles. In this study, the antimicrobial efficacy of metabolites from Rosa damascene and Citrus sinensis was evaluated. The ethanolic extracts exhibited potent antibacterial and antifungal activity, and showed high biocompatibility.
BIOMASS CONVERSION AND BIOREFINERY
(2023)
Article
Energy & Fuels
M. Lavanya, S. Karthick Raja Namasivayam, A. Praveena, S. Priyanka, M. Kavisri, Meivelu Moovendhan
Summary: Bioactive metabolites derived from medicinal plants or herbs have gained attention in biomedicine and pharmacotherapy. Polyherbal forms of plant-based medicine are believed to have greater effects and are commonly used in herbal-based products. This study investigates the anti-asthmatic activity of a herbal consortium including Euphorbia hirta, Aerva lanata linn, Solanum trilobatum, Leucas aspera, and Aegle marmelos using in silico approach. Results suggest the potential use of this herbal metabolite consortium as an effective biomedicine against asthma.
BIOMASS CONVERSION AND BIOREFINERY
(2023)
Article
Environmental Sciences
Velmurugan Puliankurichi Mookan, Rajesh Kumar Machakalai, Sundararajan Srinivasan, Sivaraj Sigamani, Prabhu Kolandhasamy, Palingamoorthy Gnanamoorthy, Meivelu Moovendhan, Ramachandran Srinivasan, Ashraf Atef Hatamleh, Munirah Abdullah AI-Dosary
Summary: The spatial concentration of heavy metals (Mn, Ni, Cu, Co, Zn, Cd, and Pb) was studied in coastal areas of Palk Bay, India. Pollution indices were calculated to evaluate the metal pollution in water and sediment, which indicated moderate contamination of sediment due to anthropogenic activities. Cadmium concentrations were the highest and positively correlated with anthropogenic sources.
MARINE POLLUTION BULLETIN
(2023)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)