Fork pausing complex engages topoisomerases at the replisome

Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner

(2019) Julien N. Bianco et al.   Nature Communications

Synergistic Coordination of Chromatin Torsional Mechanics and Topoisomerase Activity

(2019) Tung T. Le et al.   CELL

DNA polymerase ε-dependent modulation of the pausing property of the CMG helicase at the barrier

(2018) Kohji Hizume et al.   GENES & DEVELOPMENT

How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication

(2017) Joseph T.P. Yeeles et al.   MOLECULAR CELL

Regulation of DNA Replication through Natural  Impediments in the Eukaryotic Genome

(2017) Mariana Gadaleta et al.   Genes

Chromosome Duplication in Saccharomyces cerevisiae

(2016) S. P. Bell et al.   GENETICS

Roles of eukaryotic topoisomerases in transcription, replication and genomic stability

(2016) Yves Pommier et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

More than 10% of yeast genes are related to genome stability and influence cellular senescence via rDNA maintenance

(2016) Kimiko Saka et al.   NUCLEIC ACIDS RESEARCH

Budding Yeast Rif1 Controls Genome Integrity by Inhibiting rDNA Replication

(2016) Maksym Shyian et al.   PLoS Genetics

The Causes and Consequences of Topological Stress during DNA Replication

(2016) Andrea Keszthelyi et al.   Genes

ER–mitochondrial junctions can be bypassed by dominant mutations in the endosomal protein Vps13

(2015) Alexander B. Lang et al.   JOURNAL OF CELL BIOLOGY

Fork rotation and DNA precatenation are restricted during DNA replication to prevent chromosomal instability

(2015) Stephanie A. Schalbetter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Top2 and Sgs1-Top3 Act Redundantly to Ensure rDNA Replication Termination

(2015) Kamilla Mundbjerg et al.   PLoS Genetics

Tipin Functions in the Protection against Topoisomerase I Inhibitor

(2014) Yoshifumi Hosono et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reversible Top1 cleavage complexes are stabilized strand-specifically at the ribosomal replication fork barrier and contribute to ribosomal DNA stability

(2014) Claudia Krawczyk et al.   NUCLEIC ACIDS RESEARCH

HTSstation: A Web Application and Open-Access Libraries for High-Throughput Sequencing Data Analysis

(2014) Fabrice P. A. David et al.   PLoS One

The Escherichia coli Tus–Ter replication fork barrier causes site-specific DNA replication perturbation in yeast

(2014) Nicolai B. Larsen et al.   Nature Communications

Rif1 Controls DNA Replication Timing in Yeast through the PP1 Phosphatase Glc7

(2014) Stefano Mattarocci et al.   Cell Reports

Transcription-generated torsional stress destabilizes nucleosomes

(2013) Sheila S Teves et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Human Tim-Tipin complex affects the biochemical properties of the replicative DNA helicase and DNA polymerases

(2013) W.-H. Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An expanded tool kit for the auxin-inducible degron system in budding yeast

(2013) Magdalena Morawska et al.   YEAST

Replisome Stability at Defective DNA Replication Forks Is Independent of S Phase Checkpoint Kinases

(2012) Giacomo De Piccoli et al.   MOLECULAR CELL

Predicting the Functional Effect of Amino Acid Substitutions and Indels

(2012) Yongwook Choi et al.   PLoS One

Dynamics of DNA Supercoils

(2012) M. T. J. van Loenhout et al.   SCIENCE

Construction of Multidrug-Sensitive Yeast with High Sporulation Efficiency

(2011) Takumi CHINEN et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

The many facets of the Tim-Tipin protein families’ roles in chromosome biology

(2011) Ramsay J. McFarlane et al.   CELL CYCLE

Characterization of the activation domain of the Rad53 checkpoint kinase

(2010) Simona Fiorani et al.   CELL CYCLE

Discovery of Mutations in Saccharomyces cerevisiae by Pooled Linkage Analysis and Whole-Genome Sequencing

(2010) S. R. Birkeland et al.   GENETICS

Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage

(2010) R. J. D. Reid et al.   GENOME RESEARCH

The Intra-S Phase Checkpoint Protein Tof1 Collaborates with the Helicase Rrm3 and the F-box Protein Dia2 to Maintain Genome Stability inSaccharomyces cerevisiae

(2010) Narendra K. Bairwa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Csm3, Tof1, and Mrc1 Form a Heterotrimeric Mediator Complex That Associates with DNA Replication Forks

(2009) Masashige Bando et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Highly Transcribed RNA Polymerase II Genes Are Impediments to Replication Fork Progression in Saccharomyces cerevisiae

(2009) Anna Azvolinsky et al.   MOLECULAR CELL

The Anchor-Away Technique: Rapid, Conditional Establishment of Yeast Mutant Phenotypes

(2008) Hirohito Haruki et al.   MOLECULAR CELL

Topoisomerase II Inactivation Prevents the Completion of DNA Replication in Budding Yeast

(2008) Jonathan Baxter et al.   MOLECULAR CELL

Replication stalling at unstable inverted repeats: Interplay between DNA hairpins and fork stabilizing proteins

(2008) I. Voineagu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA