标题
Inhibiting DosRST as a new approach to tuberculosis therapy
作者
关键词
-
出版物
Future Medicinal Chemistry
Volume 12, Issue 5, Pages 457-467
出版商
Future Science Ltd
发表日期
2020-02-13
DOI
10.4155/fmc-2019-0263
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- A spectroelectrochemical investigation of the heme‐based sensor DevS from Mycobacterium tuberculosis : a redox versus oxygen sensor
- (2019) Giamwemberg A. Barreto et al. FEBS Journal
- Acid Fasting: Modulation of Mycobacterium tuberculosis Metabolism at Acidic pH
- (2019) Jacob J. Baker et al. TRENDS IN MICROBIOLOGY
- Inhibiting Mycobacterium tuberculosis DosRST signaling by targeting response regulator DNA binding and sensor kinase heme
- (2019) Huiqing Zheng et al. ACS Chemical Biology
- Exploration of the Effects of γ-Phosphate-Modified ATP Analogues on Histidine Kinase Autophosphorylation
- (2018) Olivia M. Chase et al. BIOCHEMISTRY
- Screening serine/threonine and tyrosine kinase inhibitors for histidine kinase inhibition
- (2018) Kaelyn E. Wilke et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Growth ofMycobacterium tuberculosisin vivo segregates with host macrophage metabolism and ontogeny
- (2018) Lu Huang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Disarming the virulence arsenal of Pseudomonas aeruginosa by blocking two-component system signaling
- (2018) Manibarsha Goswami et al. Chemical Science
- Lysine acetylation of DosR regulates the hypoxia response of Mycobacterium tuberculosis
- (2018) Hua Yang et al. Emerging Microbes & Infections
- Interplay of PhoP and DevR response regulators defines expression of the dormancy regulon in virulent Mycobacterium tuberculosis
- (2018) Atul Vashist et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Oxygen triggers signal transduction in the DevS (DosS) sensor of Mycobacterium tuberculosis by modulating the quaternary structure
- (2018) Josiane Bezerra da Silva Lobão et al. FEBS Journal
- Cognate sensor kinase-independent activation of Mycobacterium tuberculosis response regulator DevR (DosR) by acetyl phosphate: Implications in anti-mycobacterial drug design
- (2018) Saurabh Sharma et al. MOLECULAR MICROBIOLOGY
- Target DNA stabilizes Mycobacterium tuberculosis DevR/DosR phosphorylation by the full-length oxygen sensors DevS/DosS and DosT
- (2017) Eduardo H. S. Sousa et al. FEBS Journal
- Anaerobic Mycobacterium tuberculosis Cell Death Stems from Intracellular Acidification Mitigated by the DosR Regulon
- (2017) Matthew J. Reichlen et al. JOURNAL OF BACTERIOLOGY
- Small Molecules That Sabotage Bacterial Virulence
- (2017) Benjamin K. Johnson et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis
- (2017) Michael A. DeJesus et al. mBio
- Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform
- (2017) Jeremy M. Rock et al. Nature Microbiology
- Crystal structures of the CO and NO Bound DosS GAF-A domain and implications for DosS signaling in Mycobacterium tuberculosis
- (2016) Yarrow Madrona et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- DevS/DosS sensor is bifunctional and its phosphatase activity precludes aerobic DevR/DosR regulon expression inMycobacterium tuberculosis
- (2016) Kohinoor Kaur et al. FEBS Journal
- Unique Regulation of the DosR Regulon in the Beijing Lineage of Mycobacterium tuberculosis
- (2016) Pilar Domenech et al. JOURNAL OF BACTERIOLOGY
- Inhibitors of Mycobacterium tuberculosis DosRST signaling and persistence
- (2016) Huiqing Zheng et al. Nature Chemical Biology
- Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure
- (2016) Stephanus T Malherbe et al. NATURE MEDICINE
- Targeting multiple response regulators of Mycobacterium tuberculosis augments the host immune response to infection
- (2016) Srijon Kaushik Banerjee et al. Scientific Reports
- PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis
- (2016) Philana Ling Lin et al. PLoS Pathogens
- The DosR Regulon Modulates Adaptive Immunity and Is Essential forMycobacterium tuberculosisPersistence
- (2015) Smriti Mehra et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- DosS Is Required for the Complete Virulence ofMycobacterium tuberculosisin Mice with Classical Granulomatous Lesions
- (2015) Uma S. Gautam et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- A Sterilizing Tuberculosis Treatment Regimen Is Associated with Faster Clearance of Bacteria in Cavitary Lesions in Marmosets
- (2015) Laura E. Via et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- The Carbonic Anhydrase Inhibitor Ethoxzolamide Inhibits the Mycobacterium tuberculosis PhoPR Regulon and Esx-1 Secretion and Attenuates Virulence
- (2015) Benjamin K. Johnson et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- The two-component signalling networks ofMycobacterium tuberculosisdisplay extensive cross-talkin vitro
- (2015) Ruchi Agrawal et al. BIOCHEMICAL JOURNAL
- Mycobacterium tuberculosisResponse Regulators, DevR and NarL, Interactin Vivoand Co-regulate Gene Expression during Aerobic Nitrate Metabolism
- (2015) Vandana Malhotra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- In-Vivo Gene Signatures of Mycobacterium tuberculosis in C3HeB/FeJ Mice
- (2015) Uma Shankar Gautam et al. PLoS One
- The DNA-binding network of Mycobacterium tuberculosis
- (2015) Kyle J. Minch et al. Nature Communications
- Bacterial Histidine Kinases as Novel Antibacterial Drug Targets
- (2014) Agnieszka E. Bem et al. ACS Chemical Biology
- DevR (DosR) mimetic peptides impair transcriptional regulation and survival of Mycobacterium tuberculosis under hypoxia by inhibiting the autokinase activity of DevS sensor kinase
- (2014) Kohinoor Kaur et al. BMC MICROBIOLOGY
- Slow growth ofMycobacterium tuberculosisat acidic pH is regulated byphoPRand host-associated carbon sources
- (2014) Jacob J. Baker et al. MOLECULAR MICROBIOLOGY
- The Mycobacterium tuberculosis regulatory network and hypoxia
- (2013) James E. Galagan et al. NATURE
- Mycobacterium tuberculosis Responds to Chloride and pH as Synergistic Cues to the Immune Status of its Host Cell
- (2013) Shumin Tan et al. PLoS Pathogens
- A High-Throughput Screen To Identify Inhibitors of ATP Homeostasis in Non-replicating Mycobacterium tuberculosis
- (2012) Puiying A. Mak et al. ACS Chemical Biology
- DevR (DosR) binding peptide inhibits adaptation of Mycobacterium tuberculosis under hypoxia
- (2012) Sakshi Dhingra et al. FEMS MICROBIOLOGY LETTERS
- Blockage of the channel to heme by the E87 side chain in the GAF domain ofMycobacterium tuberculosisDosS confers the unique sensitivity of DosS to oxygen
- (2011) Ha Yeon Cho et al. FEBS LETTERS
- Mycobacterium tuberculosis and the intimate discourse of a chronic infection
- (2011) David G. Russell IMMUNOLOGICAL REVIEWS
- The prrAB Two-Component System Is Essential for Mycobacterium tuberculosis Viability and Is Induced under Nitrogen-Limiting Conditions
- (2011) S. E. Haydel et al. JOURNAL OF BACTERIOLOGY
- Mouse Model of Necrotic Tuberculosis Granulomas Develops Hypoxic Lesions
- (2011) Jamie Harper et al. JOURNAL OF INFECTIOUS DISEASES
- Adaptation to Environmental Stimuli within the Host: Two-Component Signal Transduction Systems of Mycobacterium tuberculosis
- (2011) D. J. Bretl et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- aprABC: a Mycobacterium tuberculosis complex-specific locus that modulates pH-driven adaptation to the macrophage phagosome
- (2011) Robert B. Abramovitch et al. MOLECULAR MICROBIOLOGY
- Metabolic Regulation of Mycobacterial Growth and Antibiotic Sensitivity
- (2011) Seung-Hun Baek et al. PLOS BIOLOGY
- Mycobacterium tuberculosis Uses Host Triacylglycerol to Accumulate Lipid Droplets and Acquires a Dormancy-Like Phenotype in Lipid-Loaded Macrophages
- (2011) Jaiyanth Daniel et al. PLoS Pathogens
- Convergence of Ser/Thr and Two-component Signaling to Coordinate Expression of the Dormancy Regulon inMycobacterium tuberculosis
- (2010) Joseph D. Chao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Anti-virulence strategies to combat bacteria-mediated disease
- (2010) David A. Rasko et al. NATURE REVIEWS DRUG DISCOVERY
- Mycobacterium tuberculosis Transcriptional Adaptation, Growth Arrest and Dormancy Phenotype Development Is Triggered by Vitamin C
- (2010) Neetu Kumra Taneja et al. PLoS One
- Biological Insights from Structures of Two-Component Proteins
- (2009) Rong Gao et al. Annual Review of Microbiology
- Unique Roles of DosT and DosS in DosR Regulon Induction and Mycobacterium tuberculosis Dormancy
- (2009) R. W. Honaker et al. INFECTION AND IMMUNITY
- The Mycobacterium tuberculosis DosR Regulon Assists in Metabolic Homeostasis and Enables Rapid Recovery from Nonrespiring Dormancy
- (2009) R. L. Leistikow et al. JOURNAL OF BACTERIOLOGY
- Structural Insight into the Heme-based Redox Sensing by DosS fromMycobacterium tuberculosis
- (2009) Ha Yeon Cho et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure-Based Design of DevR Inhibitor Active against NonreplicatingMycobacterium tuberculosis
- (2009) Rajesh Kumar Gupta et al. JOURNAL OF MEDICINAL CHEMISTRY
- Nutrient-starved, non-replicating Mycobacterium tuberculosis requires respiration, ATP synthase and isocitrate lyase for maintenance of ATP homeostasis and viability
- (2009) M. Gengenbacher et al. MICROBIOLOGY-SGM
- A Novel In Vitro Multiple-Stress Dormancy Model for Mycobacterium tuberculosis Generates a Lipid-Loaded, Drug-Tolerant, Dormant Pathogen
- (2009) Chirajyoti Deb et al. PLoS One
- The DosR regulon of M. tuberculosis and antibacterial tolerance
- (2009) I.L. Bartek et al. TUBERCULOSIS
- 2.3 Å X-ray Structure of the Heme-Bound GAF Domain of Sensory Histidine Kinase DosT ofMycobacterium tuberculosis†‡
- (2008) Larissa M. Podust et al. BIOCHEMISTRY
- Mycobacterium tuberculosis Senses Host-Derived Carbon Monoxide during Macrophage Infection
- (2008) Michael U. Shiloh et al. Cell Host & Microbe
- Role of the dosR-dosS Two-Component Regulatory System in Mycobacterium tuberculosis Virulence in Three Animal Models
- (2008) P. J. Converse et al. INFECTION AND IMMUNITY
- Heme Oxygenase-1-derived Carbon Monoxide Induces theMycobacterium tuberculosisDormancy Regulon
- (2008) Ashwani Kumar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Enduring Hypoxic Response of Mycobacterium tuberculosis
- (2008) Tige R. Rustad et al. PLoS One
- Targeting QseC Signaling and Virulence for Antibiotic Development
- (2008) D. A. Rasko et al. SCIENCE
- Cytological and Transcript Analyses Reveal Fat and Lazy Persister-Like Bacilli in Tuberculous Sputum
- (2008) Natalie J Garton et al. PLOS MEDICINE
- The biology and future prospects of antivirulence therapies
- (2007) Lynette Cegelski et al. NATURE REVIEWS MICROBIOLOGY
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