Modulation of Klotho expression in injured muscle perturbs Wnt signalling and influences the rate of muscle growth

Klotho expression is a prerequisite for proper muscle stem cell function and regeneration of skeletal muscle

(2018) Hellen E. Ahrens et al.   Skeletal Muscle

Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration

(2018) A. Sahu et al.   Nature Communications

Macrophages escape Klotho gene silencing in the mdx mouse model of Duchenne muscular dystrophy and promote muscle growth and increase satellite cell numbers through a Klotho-mediated pathway

(2017) Michelle Wehling-Henricks et al.   HUMAN MOLECULAR GENETICS

Klotho suppresses the inflammatory responses and ameliorates cardiac dysfunction in aging endotoxemic mice

(2017) Haipeng Hui et al.   Oncotarget

New Insights into the Mechanism of Action of Soluble Klotho

(2017) George D. Dalton et al.   Frontiers in Endocrinology

Comparative Study of Injury Models for Studying Muscle Regeneration in Mice

(2016) David Hardy et al.   PLoS One

Principles and standards for reporting animal experiments inThe Journal of PhysiologyandExperimental Physiology

(2015) David Grundy   EXPERIMENTAL PHYSIOLOGY

Monocyte/Macrophage-derived IGF-1 Orchestrates Murine Skeletal Muscle Regeneration and Modulates Autocrine Polarization

(2015) Joanne Tonkin et al.   MOLECULAR THERAPY

Soluble Klotho Protects against Uremic Cardiomyopathy Independently of Fibroblast Growth Factor 23 and Phosphate

(2014) J. Xie et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inducible depletion of satellite cells in adult, sedentary mice impairs muscle regenerative capacity without affecting sarcopenia

(2014) Christopher S Fry et al.   NATURE MEDICINE

Decline in muscle strength and running endurance in klotho deficient C57BL/6 mice

(2013) Michael Phelps et al.   BIOGERONTOLOGY

Loss of Klotho Contributes to Kidney Injury by Derepression of Wnt/ -Catenin Signaling

(2013) L. Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

IL-10 Triggers Changes in Macrophage Phenotype That Promote Muscle Growth and Regeneration

(2012) B. Deng et al.   JOURNAL OF IMMUNOLOGY

Proinflammatory Macrophages Enhance the Regenerative Capacity of Human Myoblasts by Modifying Their Kinetics of Proliferation and Differentiation

(2012) Maximilien Bencze et al.   MOLECULAR THERAPY

Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration

(2011) R. Sambasivan et al.   DEVELOPMENT

An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration

(2011) C. Lepper et al.   DEVELOPMENT

A WNT/β-Catenin Signaling Activator, R-spondin, Plays Positive Regulatory Roles during Skeletal Myogenesis

(2011) Xiang Hua Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Klotho Inhibits Transforming Growth Factor-β1 (TGF-β1) Signaling and Suppresses Renal Fibrosis and Cancer Metastasis in Mice

(2011) Shigehiro Doi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p38/MKP-1–regulated AKT coordinates macrophage transitions and resolution of inflammation during tissue repair

(2011) Eusebio Perdiguero et al.   JOURNAL OF CELL BIOLOGY

Dynamics of muscle fibre growth during postnatal mouse development

(2010) Robert B White et al.   BMC DEVELOPMENTAL BIOLOGY

Autophagic-lysosomal pathway functions in the masseter and tongue muscles in the klotho mouse, a mouse model for aging

(2010) Ryo-hei Iida et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

Effect of nandrolone decanoate administration on recovery from bupivacaine-induced muscle injury

(2009) James P. White et al.   JOURNAL OF APPLIED PHYSIOLOGY

A Temporal Switch from Notch to Wnt Signaling in Muscle Stem Cells Is Necessary for Normal Adult Myogenesis

(2008) Andrew S. Brack et al.   Cell Stem Cell

Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy

(2008) S. A. Villalta et al.   HUMAN MOLECULAR GENETICS

 -Catenin Interacts with MyoD and Regulates Its Transcription Activity

(2008) C.-H. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY