Emerging role of primary heterogeneous nucleation in pharmaceutical crystallization

Heterogeneous Crystallization of Fenofibrate onto Pharmaceutical Excipients

(2018) Raquel Arribas Bueno et al.   CRYSTAL GROWTH & DESIGN

Surface-induced crystallization of pharmaceuticals and biopharmaceuticals: A review

(2018) Fiora Artusio et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A new polymorph of fenofibrate prepared by polymer-mediated crystallization

(2018) Xiangjun Shi et al.   JOURNAL OF CRYSTAL GROWTH

Successful Computationally Directed Templating of Metastable Pharmaceutical Polymorphs

(2018) David H. Case et al.   CRYSTAL GROWTH & DESIGN

Heterogeneous Crystallization Inside Microporous Polymer Particles as a Process Intensification Technology for the Manufacture of Drug Formulations

(2017) Jing Ling et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Influence of Process Parameters on the Heterogeneous Nucleation of Active Pharmaceutical Ingredients onto Excipients

(2017) Raquel Arribas Bueno et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Polymorphism in phenobarbital: discovery of a new polymorph and crystal structure of elusive form V

(2016) Saikat Roy et al.   CHEMICAL COMMUNICATIONS

Isomorphous template induced crystallisation: a robust method for the targeted crystallisation of computationally predicted metastable polymorphs

(2016) Vijay K. Srirambhatla et al.   CHEMICAL COMMUNICATIONS

Can computed crystal energy landscapes help understand pharmaceutical solids?

(2016) Sarah L. Price et al.   CHEMICAL COMMUNICATIONS

Design of Heterogeneous Nuclei for Lateral Crystallization via Uniaxial Assembly of Cellulose Nanocrystals

(2016) Zihao Lu et al.   CRYSTAL GROWTH & DESIGN

Utilization of Surface Equilibria for Controlling Heterogeneous Nucleation: Making the “Disappeared” Polymorph of 3-Aminobenzensulfonic Acid “Reappear”

(2016) Mitulkumar A. Patel et al.   CRYSTAL GROWTH & DESIGN

New Metastable Packing Polymorph of Donepezil Grown on Stable Polymorph Substrates

(2016) Yeojin Park et al.   CRYSTAL GROWTH & DESIGN

Disappearing Polymorphs Revisited

(2015) Dejan-Krešimir Bučar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Crystallization of acetaminophen on chitosan films blended with different acids

(2015) Hsinyun Hsu et al.   CHEMICAL ENGINEERING SCIENCE

Control of Heterogeneous Nucleation via Rationally Designed Biocompatible Polymer Surfaces with Nanoscale Features

(2015) Li Tan et al.   CRYSTAL GROWTH & DESIGN

A New Low Melting-Point Polymorph of Fenofibrate Prepared via Talc Induced Heterogeneous Nucleation

(2015) Pratchaya Tipduangta et al.   CRYSTAL GROWTH & DESIGN

Crystal growth of progesterone metastable and stable polymorphs by polymer induced herteronucleation (PIHn) method

(2015) Andrea Mariela Araya-Sibaja et al.   CRYSTAL RESEARCH AND TECHNOLOGY

Nanocrystal formation and polymorphism of glycine

(2015) Xiaochuan Yang et al.   CRYSTENGCOMM

Mechanism of generation of drug nanocrystals in celecoxib: mannitol nanocrystalline solid dispersion

(2015) Varun Bhatt et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Effect of Mannitol on Nucleation and Crystal Growth of Amorphous Flavonoids: Implications on the Formation of Nanocrystalline Solid Dispersion

(2015) Ganesh Shete et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Building solids inside nano-space: from confined amorphous through confined solvate to confined ‘metastable’ polymorph

(2015) K. P. Nartowski et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Combined crystal structure prediction and high-pressure crystallization in rational pharmaceutical polymorph screening

(2015) M. A. Neumann et al.   Nature Communications

Modernizing Pharmaceutical Manufacturing: from Batch to Continuous Production

(2015) Sau L. Lee et al.   Journal of Pharmaceutical Innovation

Heterogeneous nucleants for crystallogenesis and bioseparation

(2015) Umang V Shah et al.   Current Opinion in Chemical Engineering

Surface Mediated Structures: Stabilization of Metastable Polymorphs on the Example of Paracetamol

(2014) Heike M. A. Ehmann et al.   CRYSTAL GROWTH & DESIGN

Template-induced polymorphic selectivity: the effects of surface chemistry and solute concentration on carbamazepine crystallisation

(2014) Jose V. Parambil et al.   CRYSTENGCOMM

Thermodynamics of fenofibrate and solubility in pure organic solvents

(2014) Samuel Watterson et al.   FLUID PHASE EQUILIBRIA

Polymorphism in Paracetamol: Evidence of Additional Forms IV and V at High Pressure

(2014) Spencer J. Smith et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Self-Association during Heterogeneous Nucleation onto Well-Defined Templates

(2014) Samir A. Kulkarni et al.   LANGMUIR

Crystallization: Key thermodynamic, kinetic and hydrodynamic aspects

(2014) SREEPRIYA VEDANTAM et al.   SADHANA-ACADEMY PROCEEDINGS IN ENGINEERING SCIENCES

ICTAC Kinetics Committee recommendations for collecting experimental thermal analysis data for kinetic computations

(2014) Sergey Vyazovkin et al.   THERMOCHIMICA ACTA

A practical guide to pharmaceutical polymorph screening & selection

(2014) Eun Hee Lee   Asian Journal of Pharmaceutical Sciences

Morphology of Porous Hosts Directs Preferred Polymorph Formation and Influences Kinetics of Solid/Solid Transitions of Confined Pharmaceuticals

(2013) Gitte Graubner et al.   CRYSTAL GROWTH & DESIGN

Impact of Crystal Habit on Biopharmaceutical Performance of Celecoxib

(2013) Sameer R. Modi et al.   CRYSTAL GROWTH & DESIGN

Geometric Design of Heterogeneous Nucleation Sites on Biocompatible Surfaces

(2013) Vilmalí López-Mejías et al.   CRYSTAL GROWTH & DESIGN

Regulating Nucleation Kinetics through Molecular Interactions at the Polymer–Solute Interface

(2013) Efrem Curcio et al.   CRYSTAL GROWTH & DESIGN

Concomitant cocrystallization on engineered surfaces

(2013) Xingyi Shi et al.   CRYSTENGCOMM

On-line near infrared spectroscopy as a Process Analytical Technology (PAT) tool to control an industrial seeded API crystallization

(2013) C. Schaefer et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Templated Nucleation of Acetaminophen on Spherical Excipient Agglomerates

(2013) Justin L. Quon et al.   LANGMUIR

The curious case of (caffeine)·(benzoic acid): how heteronuclear seeding allowed the formation of an elusive cocrystal

(2013) Dejan-Krešimir Bučar et al.   Chemical Science

From Tailored Supports to Controlled Nucleation: Exploring Material Chemistry, Surface Nanostructure, and Wetting Regime Effects in Heterogeneous Nucleation of Organic Molecules

(2012) Gianluca Di Profio et al.   CRYSTAL GROWTH & DESIGN

Polymorph Control of Micro/Nano-Sized Mefenamic Acid Crystals on Patterned Self-Assembled Monolayer Islands

(2012) Xiaochuan Yang et al.   CRYSTAL GROWTH & DESIGN

Toward the Rational Design of Crystalline Surfaces for Heteroepitaxy: Role of Molecular Functionality

(2012) Keith Chadwick et al.   CRYSTAL GROWTH & DESIGN

Crystallisation of the orthorhombic form of acetaminophen: Combined effect of surface topography and chemistry

(2012) Thomas Delmas et al.   POWDER TECHNOLOGY

Morphology study of progesterone polymorphs prepared by polymer-induced heteronucleation (PIHn)

(2012) Andrea M. A. Araya-Sibaja et al.   SCANNING

Effects of Self-Assembled Monolayers on Selective Crystallization of Tolbutamide

(2011) Jinli Zhang et al.   CRYSTAL GROWTH & DESIGN

Polymorphic control by heterogeneous nucleation - A new method for selecting crystalline substrates

(2011) Keith Chadwick et al.   CRYSTENGCOMM

Surface Design for Controlled Crystallization: The Role of Surface Chemistry and Nanoscale Pores in Heterogeneous Nucleation

(2011) Ying Diao et al.   LANGMUIR

Pharmaceutical nanocrystals

(2011) George Duo Wang et al.   Current Opinion in Chemical Engineering

Epitaxy of a Structurally Related Compound on the (100) Faces of Flufenamic Acid Form I and III Single Crystals

(2010) Eun Hee Lee et al.   CRYSTAL GROWTH & DESIGN

Crystal Nucleation Rates from Probability Distributions of Induction Times

(2010) Shanfeng Jiang et al.   CRYSTAL GROWTH & DESIGN

The two-step mechanism of nucleation of crystals in solution

(2010) Peter G. Vekilov   Nanoscale

Nucleation of Crystals from Solution: Classical and Two-Step Models

(2009) Deniz Erdemir et al.   ACCOUNTS OF CHEMICAL RESEARCH

Crystallization of Metastable Polymorphs of Phenobarbital by Isomorphic Seeding†

(2009) Neslihan Zencirci et al.   CRYSTAL GROWTH & DESIGN

Monte Carlo Test of the Classical Theory for Heterogeneous Nucleation Barriers

(2009) David Winter et al.   PHYSICAL REVIEW LETTERS

Understanding the solid-state forms of fenofibrate – A spectroscopic and computational study

(2008) A HEINZ et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS