Modernizing Pharmaceutical Manufacturing: from Batch to Continuous Production

Understanding Pharmaceutical Quality by Design

(2014) Lawrence X. Yu et al.   AAPS Journal

Supervisory Control System for Monitoring a Pharmaceutical Hot Melt Extrusion Process

(2013) Daniel Markl et al.   AAPS PHARMSCITECH

Model-based design of a plant-wide control strategy for a continuous pharmaceutical plant

(2013) Richard Lakerveld et al.   AICHE JOURNAL

End-to-End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation

(2013) Salvatore Mascia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

System-wide hybrid MPC–PID control of a continuous pharmaceutical tablet manufacturing process via direct compaction

(2013) Ravendra Singh et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Residence time modeling of hot melt extrusion processes

(2013) Elena Reitz et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Inline monitoring and a PAT strategy for pharmaceutical hot melt extrusion

(2013) Patrick R. Wahl et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Development of a methodology to estimate error in the on-line measurements of blend uniformity in a continuous powder mixing process

(2013) Aditya U. Vanarase et al.   POWDER TECHNOLOGY

An integrated approach for dynamic flowsheet modeling and sensitivity analysis of a continuous tablet manufacturing process

(2012) Fani Boukouvala et al.   COMPUTERS & CHEMICAL ENGINEERING

A Plant-Wide Dynamic Model of a Continuous Pharmaceutical Process

(2012) Brahim Benyahia et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Continuous Flow Synthesis. A Pharma Perspective

(2012) Laia Malet-Sanz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Continuous Processing in the Manufacture of Active Pharmaceutical Ingredients and Finished Dosage Forms: An Industry Perspective

(2012) Peter Poechlauer et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Pharmaceutical Crystallization

(2011) Jie Chen et al.   CRYSTAL GROWTH & DESIGN

Economic Analysis of Integrated Continuous and Batch Pharmaceutical Manufacturing: A Case Study

(2011) Spencer D. Schaber et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Improving traceability in continuous processes using flow simulations

(2011) Björn Kvarnström et al.   PRODUCTION PLANNING & CONTROL

Characterizing continuous powder mixing using residence time distribution

(2010) Yijie Gao et al.   CHEMICAL ENGINEERING SCIENCE

Continuous flow multi-step organic synthesis

(2010) Damien Webb et al.   Chemical Science