Exotoxins from Staphylococcus aureus activate 5-lipoxygenase and induce leukotriene biosynthesis

Staphylococcal Osteomyelitis: Disease Progression, Treatment Challenges, and Future Directions

(2018) Nicola Kavanagh et al.   CLINICAL MICROBIOLOGY REVIEWS

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

(2018) Oliver Werz et al.   Nature Communications

Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase

(2017) Ulrike Garscha et al.   Scientific Reports

Time-resolved in situ assembly of the leukotriene-synthetic 5-lipoxygenase/5-lipoxygenase-activating protein complex in blood leukocytes

(2016) Jana Gerstmeier et al.   FASEB JOURNAL

Neutrophil swarming: an essential process of the neutrophil tissue response

(2016) Korbinian Kienle et al.   IMMUNOLOGICAL REVIEWS

Phenol-soluble modulin α4 mediates Staphylococcus aureus-associated vascular leakage by stimulating heparin-binding protein release from neutrophils

(2016) Lin li et al.   Scientific Reports

5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease

(2015) Olof Rådmark et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

CD13 mediates phagocytosis in human monocytic cells

(2015) Ileana Licona-Limón et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Pore-forming toxins: ancient, but never really out of fashion

(2015) Matteo Dal Peraro et al.   NATURE REVIEWS MICROBIOLOGY

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Sigma Factor SigB Is Crucial to Mediate Staphylococcus aureus Adaptation during Chronic Infections

(2015) Lorena Tuchscherr et al.   PLoS Pathogens

An experimental cell-based model for studying the cell biology and molecular pharmacology of 5-lipoxygenase-activating protein in leukotriene biosynthesis

(2014) Jana Gerstmeier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Selective Activation of Human Intestinal Mast Cells by Escherichia coli Hemolysin

(2014) S. Kramer et al.   JOURNAL OF IMMUNOLOGY

Neutrophils at work

(2014) William M Nauseef et al.   NATURE IMMUNOLOGY

Staphylococcal alpha-phenol soluble modulins contribute to neutrophil lysis after phagocytosis

(2013) B. G. J. Surewaard et al.   CELLULAR MICROBIOLOGY

An insight into pleiotropic regulators Agr and Sar: molecular probes paving the new way for antivirulent therapy

(2013) Rekha Arya et al.   Future Microbiology

The impact of α-toxin on host cell plasma membrane permeability and cytokine expression during human blood infection by CA-MRSA USA300

(2013) Tyler K. Nygaard et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Role of Pore-Forming Toxins in Bacterial Infectious Diseases

(2013) F. C. O. Los et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo

(2013) Tim Lämmermann et al.   NATURE

Phenol-soluble modulins and staphylococcal infection

(2013) Andreas Peschel et al.   NATURE REVIEWS MICROBIOLOGY

Cell targeting by the Staphylococcus aureus pore-forming toxins: it's not just about lipids

(2013) Ashley L. DuMont et al.   TRENDS IN MICROBIOLOGY

Pathogenic Pore-Forming Proteins: Function and Host Response

(2012) Mirko Bischofberger et al.   Cell Host & Microbe

The Stringent Response of Staphylococcus aureus and Its Impact on Survival after Phagocytosis through the Induction of Intracellular PSMs Expression

(2012) Tobias Geiger et al.   PLoS Pathogens

Involvement of red blood cells in the regulation of leukotriene synthesis in polymorphonuclear leucocytes upon interaction with Salmonella Typhimurium

(2011) EKATERINA A. GOLENKINA et al.   APMIS

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor

(2011) Solveigh C Koeberle et al.   Nature Chemical Biology

Human Formyl Peptide Receptor 2 Senses Highly Pathogenic Staphylococcus aureus

(2010) Dorothee Kretschmer et al.   Cell Host & Microbe

Subcutaneous Infection with S. aureus in Mice Reveals Association of Resistance with Influx of Neutrophils and Th2 Response

(2010) Nadine Nippe et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Community-associated meticillin-resistant Staphylococcus aureus

(2010) Frank R DeLeo et al.   LANCET

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Role of MAPK p38 in the cellular responses to pore-forming toxins

(2010) Helena Porta et al.   PEPTIDES

Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus  -hemolysin-mediated cellular injury

(2010) G. A. Wilke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Staphylococcus epidermidis Strategies to Avoid Killing by Human Neutrophils

(2010) Gordon Y. C. Cheung et al.   PLoS Pathogens

Staphylococcus aureus Panton-Valentine Leukocidin Is a Very Potent Cytotoxic Factor for Human Neutrophils

(2010) Bettina Löffler et al.   PLoS Pathogens

Discovery of virulence factors of pathogenic bacteria

(2008) Hsing-Ju Wu et al.   CURRENT OPINION IN CHEMICAL BIOLOGY