The effect of inhibition of PP1 and TNFα signaling on pathogenesis of SARS coronavirus

Identification of Important Nodes in Directed Biological Networks: A Network Motif Approach

(2014) Pei Wang et al.   PLoS One

Pathogenic Influenza Viruses and Coronaviruses Utilize Similar and Contrasting Approaches To Control Interferon-Stimulated Gene Responses

(2014) V. D. Menachery et al.   mBio

Systems infection biology: a compartmentalized immune network of pig spleen challenged with Haemophilus parasuis

(2013) Ming Zhao et al.   BMC GENOMICS

A Systems Analysis Identifies a Feedforward Inflammatory Circuit Leading to Lethal Influenza Infection

(2013) Marlène Brandes et al.   CELL

Inhibition of NF- B-Mediated Inflammation in Severe Acute Respiratory Syndrome Coronavirus-Infected Mice Increases Survival

(2013) M. L. DeDiego et al.   JOURNAL OF VIROLOGY

Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Announcement of the Coronavirus Study Group

(2013) R. J. de Groot et al.   JOURNAL OF VIROLOGY

Mechanisms of Severe Acute Respiratory Syndrome Coronavirus-Induced Acute Lung Injury

(2013) L. E. Gralinski et al.   mBio

Cell Host Response to Infection with Novel Human Coronavirus EMC Predicts Potential Antivirals and Important Differences with SARS Coronavirus

(2013) L. Josset et al.   mBio

CXCL10-CXCR3 Enhances the Development of Neutrophil-mediated Fulminant Lung Injury of Viral and Nonviral Origin

(2012) Akihiko Ichikawa et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Topological analysis of protein co-abundance networks identifies novel host targets important for HCV infection and pathogenesis

(2012) Jason E McDermott et al.   BMC Systems Biology

Integration of disease-specific single nucleotide polymorphisms, expression quantitative trait loci and coexpression networks reveal novel candidate genes for type 2 diabetes

(2012) H. P. Kang et al.   DIABETOLOGIA

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Validation of Ifit1 as an Important Innate Immune Bottleneck

(2012) Jason E. McDermott et al.   PLoS One

Ten Years of Pathway Analysis: Current Approaches and Outstanding Challenges

(2012) Purvesh Khatri et al.   PLoS Computational Biology

Systems analysis of multiple regulator perturbations allows discovery of virulence factors in Salmonella

(2011) Hyunjin Yoon et al.   BMC Systems Biology

Systems Virology Identifies a Mitochondrial Fatty Acid Oxidation Enzyme, Dodecenoyl Coenzyme A Delta Isomerase, Required for Hepatitis C Virus Replication and Likely Pathogenesis

(2011) A. L. Rasmussen et al.   JOURNAL OF VIROLOGY

Host Regulatory Network Response to Infection with Highly Pathogenic H5N1 Avian Influenza Virus

(2011) C. Li et al.   JOURNAL OF VIROLOGY

A model of cyclic transcriptomic behavior in the cyanobacterium Cyanothece sp. ATCC 51142

(2011) Jason E. McDermott et al.   Molecular BioSystems

Controlling the Response: Predictive Modeling of a Highly Central, Pathogen-Targeted Core Response Module in Macrophage Activation

(2011) Jason E. McDermott et al.   PLoS One

Induction of TNF-α in human macrophages by avian and human influenza viruses

(2010) Yuwarat Monteerarat et al.   ARCHIVES OF VIROLOGY

SARS-CoV Pathogenesis Is Regulated by a STAT1 Dependent but a Type I, II and III Interferon Receptor Independent Mechanism

(2010) Matthew B. Frieman et al.   PLoS Pathogens

Weighted gene co-expression network analysis of the peripheral blood from Amyotrophic Lateral Sclerosis patients

(2009) Christiaan GJ Saris et al.   BMC GENOMICS

Cyclooxygenase-2 mediates hydrogen peroxide-induced wound repair in human endothelial cells

(2009) Sonia Eligini et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of Cellular Protein Phosphatase-1 (PP1) by Phosphorylation of the CPI-17 Family, C-kinase-activated PP1 Inhibitors

(2009) Masumi Eto   JOURNAL OF BIOLOGICAL CHEMISTRY

Bottlenecks and Hubs in Inferred Networks Are Important for Virulence in Salmonella typhimurium

(2009) Jason E. McDermott et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Cellular Immune Responses to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Infection in Senescent BALB/c Mice: CD4+ T Cells Are Important in Control of SARS-CoV Infection

(2009) J. Chen et al.   JOURNAL OF VIROLOGY

From Promiscuity to Precision: Protein Phosphatases Get a Makeover

(2009) David M. Virshup et al.   MOLECULAR CELL

Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1

(2008) Hui-Yan Li et al.   NATURE IMMUNOLOGY

MyD88 Is Required for Protection from Lethal Infection with a Mouse-Adapted SARS-CoV

(2008) Timothy Sheahan et al.   PLoS Pathogens

Quantitative systems-level determinants of human genes targeted by successful drugs

(2007) L. Yao et al.   GENOME RESEARCH