Plant-produced chimeric virus-like particles - a new generation vaccine against African horse sickness

The immunogenicity of recombinant vaccines based on modified Vaccinia Ankara (MVA) viruses expressing African horse sickness virus VP2 antigens depends on the levels of expressed VP2 protein delivered to the host

(2018) Eva Calvo-Pinilla et al.   ANTIVIRAL RESEARCH

Dimethylformamide is a novel nitrilase inducer in Rhodococcus rhodochrous

(2018) V. P. Chhiba-Govindjee et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A field investigation of an African horse sickness outbreak in the controlled area of South Africa in 2016

(2018) John Duncan Grewar et al.   Transboundary and Emerging Diseases

A single dose of African horse sickness virus (AHSV) VP2 based vaccines provides complete clinical protection in a mouse model

(2018) Mine Aksular et al.   VACCINE

Immunogenicity of plant-produced African horse sickness virus-like particles: implications for a novel vaccine

(2017) Susan J. Dennis et al.   PLANT BIOTECHNOLOGY JOURNAL

Vaccination with recombinant Modified Vaccinia Ankara (MVA) viruses expressing single African horse sickness virus VP2 antigens induced cross-reactive virus neutralising antibodies (VNAb) in horses when administered in combination

(2017) Nicola Mary Manning et al.   VACCINE

Protective efficacy of multivalent replication-abortive vaccine strains in horses against African horse sickness virus challenge

(2017) Valeria Lulla et al.   VACCINE

Antibodies from plants for bionanomaterials

(2017) Gueven Edgue et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Synthetic plant virology for nanobiotechnology and nanomedicine

(2017) John F. C. Steele et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

The case for plant-made veterinary immunotherapeutics

(2016) Edward Topp et al.   BIOTECHNOLOGY ADVANCES

Molecular pharming — VLPs made in plants

(2016) Johanna Marsian et al.   CURRENT OPINION IN BIOTECHNOLOGY

Assembly of Replication-Incompetent African Horse Sickness Virus Particles: Rational Design of Vaccines for All Serotypes

(2016) Valeria Lulla et al.   JOURNAL OF VIROLOGY

Requirements and comparative analysis of reverse genetics for bluetongue virus (BTV) and African horse sickness virus (AHSV)

(2016) Piet A. van Rijn et al.   Virology Journal

Synthesis of empty african horse sickness virus particles

(2016) Sonja Maree et al.   VIRUS RESEARCH

VP2 Exchange and NS3/NS3a Deletion in African Horse Sickness Virus (AHSV) in Development of Disabled Infectious Single Animal Vaccine Candidates for AHSV

(2015) Sandra G. P. van de Water et al.   JOURNAL OF VIROLOGY

When plant virology metAgrobacterium: the rise of the deconstructed clones

(2015) Hadrien Peyret et al.   PLANT BIOTECHNOLOGY JOURNAL

Directed genetic modification of African horse sickness virus by reverse genetics

(2015) Elaine Vermaak et al.   SOUTH AFRICAN JOURNAL OF SCIENCE

Application of Bluetongue Disabled Infectious Single Animal (DISA) vaccine for different serotypes by VP2 exchange or incorporation of chimeric VP2

(2015) Femke Feenstra et al.   VACCINE

Immunogenicity of recombinant VP2 proteins of all nine serotypes of African horse sickness virus

(2014) Yuta Kanai et al.   VACCINE

Serological response of foals to polyvalent and monovalent live-attenuated African horse sickness virus vaccines

(2014) J.E. Crafford et al.   VACCINE

Vaccination of horses with a recombinant modified vaccinia Ankara virus (MVA) expressing African horse sickness (AHS) virus major capsid protein VP2 provides complete clinical protection against challenge

(2014) Berta Alberca et al.   VACCINE

Plant-based vaccines against viruses

(2014) Edward P Rybicki   Virology Journal

Comparative Evaluation of Recombinant Protein Production in Different Biofactories: The Green Perspective

(2014) Matilde Merlin et al.   Biomed Research International

Rapid Generation of Replication-Deficient Monovalent and Multivalent Vaccines for Bluetongue Virus: Protection against Virulent Virus Challenge in Cattle and Sheep

(2013) C. C. P. Celma et al.   JOURNAL OF VIROLOGY

A method for rapid production of heteromultimeric protein complexes in plants: assembly of protective bluetongue virus-like particles

(2013) Eva C. Thuenemann et al.   PLANT BIOTECHNOLOGY JOURNAL

Passive transfer and rate of decay of maternal antibody against African horse sickness virus in South African Thoroughbred foals

(2012) J. E. Crafford et al.   EQUINE VETERINARY JOURNAL

Structural Insight into African Horsesickness Virus Infection

(2012) V. Manole et al.   JOURNAL OF VIROLOGY

Risk of introducing African horse sickness virus into the Netherlands by international equine movements

(2012) C.J. de Vos et al.   PREVENTIVE VETERINARY MEDICINE

Virus-like particles as a highly efficient vaccine platform: Diversity of targets and production systems and advances in clinical development

(2012) Natasha Kushnir et al.   VACCINE

Bluetongue virus serotype 8 virus-like particles protect sheep against virulent virus infection as a single or multi-serotype cocktail immunogen

(2012) Meredith Stewart et al.   VACCINE

An African horse sickness virus serotype 4 recombinant canarypox virus vaccine elicits specific cell-mediated immune responses in horses

(2012) H. El Garch et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Recovery and purification of plant-made recombinant proteins

(2011) Lisa R. Wilken et al.   BIOTECHNOLOGY ADVANCES

Clinical development of plant-produced recombinant pharmaceuticals: Vaccines, antibodies and beyond

(2011) Vidadi Yusibov et al.   Human vaccines & immunotherapeutics

Generation of Replication-Defective Virus-Based Vaccines That Confer Full Protection in Sheep against Virulent Bluetongue Virus Challenge

(2011) E. Matsuo et al.   JOURNAL OF VIROLOGY

In vivo cross-protection to African horse sickness Serotypes 5 and 9 after vaccination with Serotypes 8 and 6

(2010) Beate F. von Teichman et al.   VACCINE

pEAQ: versatile expression vectors for easy and quick transient expression of heterologous proteins in plants

(2009) Frank Sainsbury et al.   PLANT BIOTECHNOLOGY JOURNAL

Protective immunization of horses with a recombinant canarypox virus vectored vaccine co-expressing genes encoding the outer capsid proteins of African horse sickness virus

(2009) Alan J. Guthrie et al.   VACCINE

Validation of a novel approach for the rapid production of immunogenic virus-like particles for bluetongue virus

(2009) M. Stewart et al.   VACCINE

The coming of age of virus-like particle vaccines

(2008) Gary T. Jennings et al.   BIOLOGICAL CHEMISTRY

Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure

(2008) Richard Strasser et al.   PLANT BIOTECHNOLOGY JOURNAL

Evaluation of the pathogenicity of African Horsesickness (AHS) isolates in vaccinated animals

(2008) Beate F. von Teichman et al.   VACCINE