Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy

Illuminating spatial A-to-I RNA editing signatures within the Drosophila brain

(2019) Anne L. Sapiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TAK 1 converts Sequestosome 1/p62 from an autophagy receptor to a signaling platform

(2019) Stephanie R Kehl et al.   EMBO REPORTS

Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission

(2018) Sven Truckenbrodt et al.   EMBO JOURNAL

ADAR2-mediated Q/R editing of GluK2 regulates kainate receptor upscaling in response to suppression of synaptic activity

(2018) Sonam Gurung et al.   JOURNAL OF CELL SCIENCE

Chaperone-mediated autophagy and endosomal microautophagy: Jointed by a chaperone

(2017) Kumsal Tekirdag et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ADAR RNA editing below the backbone

(2017) Liam Keegan et al.   RNA

The evolution and adaptation of A-to-I RNA editing

(2017) Arielle L. Yablonovitch et al.   PLoS Genetics

Selective endosomal microautophagy is starvation-inducible in Drosophila

(2016) Anindita Mukherjee et al.   Autophagy

TOR and paradigm change: cell growth is controlled

(2016) Michael N. Hall   MOLECULAR BIOLOGY OF THE CELL

ADARB1 catalyzes circadian A-to-I editing and regulates RNA rhythm

(2016) Hideki Terajima et al.   NATURE GENETICS

Memory-Relevant Mushroom Body Output Synapses Are Cholinergic

(2016) Oliver Barnstedt et al.   NEURON

ADAR-mediated RNA editing suppresses sleep by acting as a brake on glutamatergic synaptic plasticity

(2016) J. E. Robinson et al.   Nature Communications

Hsc70-4 Deforms Membranes to Promote Synaptic Protein Turnover by Endosomal Microautophagy

(2015) Valerie Uytterhoeven et al.   NEURON

A Voltage-Gated Calcium Channel Regulates Lysosomal Fusion with Endosomes and Autophagosomes and Is Required for Neuronal Homeostasis

(2015) Xuejun Tian et al.   PLOS BIOLOGY

Atg17/FIP200 localizes to perilysosomal Ref(2)P aggregates and promotes autophagy by activation of Atg1 inDrosophila

(2014) Péter Nagy et al.   Autophagy

Spatial Control of the TSC Complex Integrates Insulin and Nutrient Regulation of mTORC1 at the Lysosome

(2014) Suchithra Menon et al.   CELL

JAK/STAT pathway dysregulation in tumors: A Drosophila perspective

(2014) Marc Amoyel et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA

(2014) Niamh M. Mannion et al.   Cell Reports

A type I interferon signature identifies bilateral striatal necrosis due to mutations inADAR1

(2013) John H Livingston et al.   JOURNAL OF MEDICAL GENETICS

Genome-wide analysis of A-to-I RNA editing by single-molecule sequencing in Drosophila

(2013) Georges St Laurent et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The ADAR RNA editing enzyme controls neuronal excitability in Drosophila melanogaster

(2013) X. Li et al.   NUCLEIC ACIDS RESEARCH

Reciprocal regulation of A-to-I RNA editing and the vertebrate nervous system

(2013) Andrew C. Penn et al.   Frontiers in Neuroscience

Adar is essential for optimal presynaptic function

(2012) Carolina Maldonado et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

(2012) Gillian I Rice et al.   NATURE GENETICS

The Presynaptic Active Zone

(2012) Thomas C. Südhof   NEURON

Anaplastic Lymphoma Kinase Spares Organ Growth during Nutrient Restriction in Drosophila

(2011) Louise Y. Cheng et al.   CELL

p62 Is a Key Regulator of Nutrient Sensing in the mTORC1 Pathway

(2011) Angeles Duran et al.   MOLECULAR CELL

Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein

(2011) Balpreet Bhogal et al.   NATURE NEUROSCIENCE

Functional conservation in human and Drosophila of Metazoan ADAR2 involved in RNA editing: loss of ADAR1 in insects

(2011) Liam P. Keegan et al.   NUCLEIC ACIDS RESEARCH

A small pool of vesicles maintains synaptic activity in vivo

(2011) A. Denker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The reserve pool of synaptic vesicles acts as a buffer for proteins involved in synaptic vesicle recycling

(2011) A. Denker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy takes flight in Drosophila

(2010) Yu-Yun Chang et al.   FEBS LETTERS

Engineered Alterations in RNA Editing Modulate Complex Behavior inDrosophila

(2010) James E. C. Jepson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The developmental transcriptome of Drosophila melanogaster

(2010) Brenton R. Graveley et al.   NATURE

Autophagy Suppresses Tumorigenesis through Elimination of p62

(2009) Robin Mathew et al.   CELL

Ref(2)P, theDrosophila melanogasterhomologue of mammalian p62, is required for the formation of protein aggregates in adult brain

(2008) Ioannis P. Nezis et al.   JOURNAL OF CELL BIOLOGY