标题
Nucleophosmin: from structure and function to disease development
作者
关键词
Nucleophosmin 1, DNA repair, Cancer, Apoptosis
出版物
BMC MOLECULAR BIOLOGY
Volume 17, Issue 1, Pages -
出版商
Springer Nature
发表日期
2016-08-24
DOI
10.1186/s12867-016-0073-9
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Benefit of high-dose daunorubicin in AML induction extends across cytogenetic and molecular groups
- (2016) M. R. Luskin et al. BLOOD
- Nucleophosmin Mutants Promote Adhesion, Migration and Invasion of Human Leukemia THP-1 Cells through MMPs Up-regulation via Ras/ERK MAPK Signaling
- (2016) Jingrong Xian et al. International Journal of Biological Sciences
- Repair Pathway Choices and Consequences at the Double-Strand Break
- (2016) Raphael Ceccaldi et al. TRENDS IN CELL BIOLOGY
- Implication of NPM1 phosphorylation and preclinical evaluation of the nucleoprotein antagonist N6L in prostate cancer
- (2016) Damien Destouches et al. Oncotarget
- 1-Benzyl-2-methyl-3-indolylmethylene barbituric acid derivatives: Anti-cancer agents that target nucleophosmin 1 (NPM1)
- (2015) Narsimha Reddy Penthala et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells
- (2015) M. P. Martelli et al. BLOOD
- Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells
- (2015) H. El Hajj et al. BLOOD
- Selective Toxicity of Investigational Ixazomib for Human Leukemia Cells Expressing Mutant Cytoplasmic NPM1: Role of Reactive Oxygen Species
- (2015) J. S. Garcia et al. CLINICAL CANCER RESEARCH
- Roles of mutagenic translesion synthesis in mammalian genome stability, health and disease
- (2015) Jacob G. Jansen et al. DNA REPAIR
- Inhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti-tumor properties
- (2015) Mattia Poletto et al. MOLECULAR CARCINOGENESIS
- Excess of NPM-ALK oncogenic signaling promotes cellular apoptosis and drug dependency
- (2015) M Ceccon et al. ONCOGENE
- NPM1 histone chaperone is upregulated in glioblastoma to promote cell survival and maintain nucleolar shape
- (2015) Karl Holmberg Olausson et al. Scientific Reports
- Expression and Prognostic Significance of APE1/Ref-1 and NPM1 Proteins in High-Grade Ovarian Serous Cancer
- (2014) Ambrogio P. Londero et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- Deregulated expression of Nucleophosmin 1 in gastric cancer and its clinicopathological implications
- (2014) Mariana Ferreira Leal et al. BMC GASTROENTEROLOGY
- Estrogen mediated expression of nucleophosmin 1 in human endometrial carcinoma clinical stages through estrogen receptor-α signaling
- (2014) Yunxiao Zhou et al. Cancer Cell International
- Insight in the multilevel regulation of NER
- (2014) Madelon Dijk et al. EXPERIMENTAL CELL RESEARCH
- Targeting Nucleophosmin 1 Represents a Rational Strategy for Radiation Sensitization
- (2014) Konjeti R. Sekhar et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Acute myeloid leukemia in patients older than 75: prognostic impact ofFLT3-ITDandNPM1mutations
- (2014) Pierre Hirsch et al. LEUKEMIA & LYMPHOMA
- Nucleophosmin modulates stability, activity, and nucleolar accumulation of base excision repair proteins
- (2014) Mattia Poletto et al. MOLECULAR BIOLOGY OF THE CELL
- Extrinsic Apoptosis Is Impeded by Direct Binding of the APL Fusion Protein NPM-RAR to TRADD
- (2014) A. Chattopadhyay et al. MOLECULAR CANCER RESEARCH
- NPM1 Silencing Reduces Tumour Growth and MAPK Signalling in Prostate Cancer Cells
- (2014) Gaëlle Loubeau et al. PLoS One
- Structural polymorphism in the N-terminal oligomerization domain of NPM1
- (2014) D. M. Mitrea et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of novel DNA-damage tolerance genes reveals regulation of translesion DNA synthesis by nucleophosmin
- (2014) Omer Ziv et al. Nature Communications
- CD133 and CD133-regulated nucleophosmin linked to 5-fluorouracil susceptibility in human colon cancer cell line SW620
- (2013) Kyung-Hee Kim et al. ELECTROPHORESIS
- Nucleophosmin 1, upregulated in adenomas and cancers of the colon, inhibits p53-mediated cellular senescence
- (2013) John C.T. Wong et al. INTERNATIONAL JOURNAL OF CANCER
- Role of cysteine 288 in nucleophosmin cytoplasmic mutations: sensitization to toxicity induced by arsenic trioxide and bortezomib
- (2013) M Huang et al. LEUKEMIA
- MutatedNPM1in patients with acute myeloid leukemia in remission and relapse
- (2013) Preetesh Jain et al. LEUKEMIA & LYMPHOMA
- Base Excision Repair
- (2013) H. E. Krokan et al. Cold Spring Harbor Perspectives in Biology
- Enhanced levels of double-strand DNA break repair proteins protect ovarian cancer cells against genotoxic stress-induced apoptosis
- (2013) Rajkumar Kalra et al. Journal of Ovarian Research
- Erythroid differentiation-associated gene interacts with NPM1 (nucleophosmin/B23) and increases its protein stability, resisting cell apoptosis
- (2012) Mei-Jiang Zhang et al. FEBS Journal
- Knockdown of NPM1 by RNA Interference Inhibits Cells Proliferation and Induces Apoptosis in Leukemic Cell Line
- (2012) Feng-Xian Qin et al. International Journal of Medical Sciences
- Nucleophosmin (NPM1/B23) Interacts with Activating Transcription Factor 5 (ATF5) Protein and Promotes Proteasome- and Caspase-dependent ATF5 Degradation in Hepatocellular Carcinoma Cells
- (2012) Xijun Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An Extensive Tumor Array Analysis Supports Tumor Suppressive Role for Nucleophosmin in Breast Cancer
- (2011) Piia-Riitta Karhemo et al. AMERICAN JOURNAL OF PATHOLOGY
- Crystal Structure and Function of Human Nucleoplasmin (Npm2): A Histone Chaperone in Oocytes and Embryos
- (2011) Olga Platonova et al. BIOCHEMISTRY
- The Multifunctional Protein Nucleophosmin (NPM1) Is a Human Linker Histone H1 Chaperone
- (2011) Shrikanth S. Gadad et al. BIOCHEMISTRY
- Nucleophosmin Delocalization in Thyroid Tumour Cells
- (2011) Annalisa Pianta et al. ENDOCRINE PATHOLOGY
- Integrative nucleophosmin mutation-associated microRNA and gene expression pattern analysis identifies novel microRNA - target gene interactions in acute myeloid leukemia
- (2011) A. C. Russ et al. HAEMATOLOGICA
- Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice
- (2011) George S Vassiliou et al. NATURE GENETICS
- Nucleophosmin is overexpressed in thyroid tumors
- (2010) Annalisa Pianta et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mutant nucleophosmin deregulates cell death and myeloid differentiation through excessive caspase-6 and -8 inhibition
- (2010) S. M. Leong et al. BLOOD
- Recruitment of Phosphorylated NPM1 to Sites of DNA Damage through RNF8-Dependent Ubiquitin Conjugates
- (2010) A. Koike et al. CANCER RESEARCH
- Understanding different functions of mammalian AP endonuclease (APE1) as a promising tool for cancer treatment
- (2010) Gianluca Tell et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Nucleophosmin, p53, and Ki-67 expression patterns on an oral squamous cell carcinoma tissue microarray
- (2010) Cláudia Malheiros Coutinho-Camillo et al. HUMAN PATHOLOGY
- Dephosphorylation of Nucleophosmin by PP1β Facilitates pRB Binding and Consequent E2F1-dependent DNA Repair
- (2010) Chiao Yun Lin et al. MOLECULAR BIOLOGY OF THE CELL
- Genomic instability — an evolving hallmark of cancer
- (2010) Simona Negrini et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model
- (2009) K. Cheng et al. BLOOD
- The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
- (2009) J. W. Vardiman et al. BLOOD
- Nucleophosmin Blocks Mitochondrial Localization of p53 and Apoptosis
- (2009) Sanjit Kumar Dhar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- GAGE, an Antiapoptotic Protein Binds and Modulates the Expression of Nucleophosmin/B23 and Interferon Regulatory Factor 1
- (2009) Rupinder K. Kular et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- APE1/Ref-1 Interacts with NPM1 within Nucleoli and Plays a Role in the rRNA Quality Control Process
- (2009) C. Vascotto et al. MOLECULAR AND CELLULAR BIOLOGY
- Anticancer peptide CIGB-300 binds to nucleophosmin/B23, impairs its CK2-mediated phosphorylation, and leads to apoptosis through its nucleolar disassembly activity
- (2009) Y. Perera et al. MOLECULAR CANCER THERAPEUTICS
- RNA aptamers interfering with nucleophosmin oligomerization induce apoptosis of cancer cells
- (2009) Y Jian et al. ONCOGENE
- Mechanism of Eukaryotic Homologous Recombination
- (2008) Joseph San Filippo et al. Annual Review of Biochemistry
- Depletion of nucleophosmin leads to distortion of nucleolar and nuclear structures in HeLa cells
- (2008) Mohammed Abdullahel Amin et al. BIOCHEMICAL JOURNAL
- Lysine 263 residue of NPM/B23 is essential for regulating ATP binding and B23 stability
- (2008) Joung Woo Choi et al. FEBS LETTERS
- Nucleophosmin is required for chromosome congression, proper mitotic spindle formation, and kinetochore-microtubule attachment in HeLa cells
- (2008) Mohammed Abdullahel Amin et al. FEBS LETTERS
- Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7γ
- (2008) Paola Bonetti et al. JOURNAL OF CELL BIOLOGY
- Transcription Regulation of the rRNA Gene by a Multifunctional Nucleolar Protein, B23/Nucleophosmin, through Its Histone Chaperone Activity
- (2008) K. Murano et al. MOLECULAR AND CELLULAR BIOLOGY
- NSC348884, a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis in human cancer cells
- (2008) W Qi et al. ONCOGENE
- Nuclear Akt interacts with B23/NPM and protects it from proteolytic cleavage, enhancing cell survival
- (2008) S. B. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now