Modeling hormonal and inflammatory contributions to preterm and term labor using uterine temporal transcriptomics

Maternal and fetal roles in bacterially induced preterm labor in the mouse

(2016) Yana Filipovich et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Depletion of polymorphonuclear leukocytes has no effect on preterm delivery in a mouse model of Escherichia coli-induced labor

(2015) Yana Filipovich et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Specific Lipopolysaccharide Serotypes Induce Differential Maternal and Neonatal Inflammatory Responses in a Murine Model of Preterm Labor

(2015) Roberta Migale et al.   AMERICAN JOURNAL OF PATHOLOGY

Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition

(2015) Lu Gao et al.   JOURNAL OF CLINICAL INVESTIGATION

Global, regional, and national causes of child mortality in 2000–13, with projections to inform post-2015 priorities: an updated systematic analysis

(2015) Li Liu et al.   LANCET

Ovarian Steroid Hormone-Regulated Uterine Remodeling Occurs Independently of Macrophages in Mice1

(2014) Alison S. Care et al.   BIOLOGY OF REPRODUCTION

Activator protein 1 is a key terminal mediator of inflammation-induced preterm labor in mice

(2014) David A. MacIntyre et al.   FASEB JOURNAL

Decidual Neutrophil Infiltration Is Not Required for Preterm Birth in a Mouse Model of Infection-Induced Preterm Labor

(2014) S. F. Rinaldi et al.   JOURNAL OF IMMUNOLOGY

Diminished hERG K+ channel activity facilitates strong human labour contractions but is dysregulated in obese women

(2014) Helena C. Parkington et al.   Nature Communications

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Assessment of myometrial transcriptome changes associated with spontaneous human labour by high-throughput RNA-seq

(2013) Yi-Wah Chan et al.   EXPERIMENTAL PHYSIOLOGY

Lipopolysaccharide promotes contraction of uterine myocytes via activation of Rho/ROCK signaling pathways

(2013) James L. Hutchinson et al.   FASEB JOURNAL

Transcriptome interrogation of human myometrium identifies differentially expressed sense-antisense pairs of protein-coding and long non-coding RNA genes in spontaneous labor at term

(2013) Roberto Romero et al.   Journal of Maternal-Fetal & Neonatal Medicine

Software for Computing and Annotating Genomic Ranges

(2013) Michael Lawrence et al.   PLoS Computational Biology

Mice Deficient in Surfactant Protein A (SP-A) and SP-D or in TLR2 Manifest Delayed Parturition and Decreased Expression of Inflammatory and Contractile Genes

(2012) Alina P. Montalbano et al.   ENDOCRINOLOGY

Interactions between inflammatory signals and the progesterone receptor in regulating gene expression in pregnant human uterine myocytes

(2012) Yun Lee et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Myometrial immune cells contribute to term parturition, preterm labour and post-partum involution in mice

(2012) Oksana Shynlova et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Progesterone Receptor-A and -B Have Opposite Effects on Proinflammatory Gene Expression in Human Myometrial Cells: Implications for Progesterone Actions in Human Pregnancy and Parturition

(2012) Huiqing Tan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Prevention of preterm labour via the modulation of inflammatory pathways

(2012) David A. MacIntyre et al.   Journal of Maternal-Fetal & Neonatal Medicine

Longitudinal Analysis of Maternal Plasma Apolipoproteins in Pregnancy: A Targeted Proteomics Approach

(2012) Shannon K. Flood-Nichols et al.   MOLECULAR & CELLULAR PROTEOMICS

Nuclear Factor Kappa B Activation Occurs in the Amnion Prior to Labour Onset and Modulates the Expression of Numerous Labour Associated Genes

(2012) Sheri Lim et al.   PLoS One

The Molecular Mechanisms of Cervical Ripening Differ between Term and Preterm Birth

(2011) Roxane Holt et al.   ENDOCRINOLOGY

Mast cells reside in myometrium and cervix, but are dispensable in mice for successful pregnancy and labor

(2011) Fiona M Menzies et al.   IMMUNOLOGY AND CELL BIOLOGY

Intrauterine inflammation, insufficient to induce parturition, still evokes fetal and neonatal brain injury

(2011) Michal A. Elovitz et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Characterization of the transcriptome of chorioamniotic membranes at the site of rupture in spontaneous labor at term

(2010) Chia-Ling Nhan-Chang et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Preventing preterm birth: the past limitations and new potential of animal models

(2010) C. K. Ratajczak et al.   Disease Models & Mechanisms

Characterization of the myometrial transcriptome and biological pathways of spontaneous human labor at term

(2010) Pooja Mittal et al.   JOURNAL OF PERINATAL MEDICINE

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Preterm and Term Cervical Ripening in CD1 Mice (Mus musculus): Similar or Divergent Molecular Mechanisms?1

(2009) Juan M. Gonzalez et al.   BIOLOGY OF REPRODUCTION

Reduction in TRPC4 expression specifically attenuates G-protein coupled receptor-stimulated increases in intracellular calcium in human myometrial cells

(2009) Aida Ulloa et al.   CELL CALCIUM

The Cyclopentenone 15-Deoxy-Δ12,14-Prostaglandin J2Delays Lipopolysaccharide-Induced Preterm Delivery and Reduces Mortality in the Newborn Mouse

(2008) Grisha Pirianov et al.   ENDOCRINOLOGY

Epidemiology and causes of preterm birth

(2008) Robert L Goldenberg et al.   LANCET

Changes in global gene expression in rat myometrium in transition from late pregnancy to parturition

(2008) Gustavo Helguera et al.   PHYSIOLOGICAL GENOMICS