Mass Activated Droplet Sorting (MADS) Enables High-Throughput Screening of Enzymatic Reactions at Nanoliter Scale

Activity-Based DNA-Encoded Library Screening

(2019) Wesley G. Cochrane et al.   ACS Combinatorial Science

Ultrahigh-throughput screening enables efficient single-round oxidase remodelling

(2019) Aaron Debon et al.   Nature Catalysis

An integrated chip-mass spectrometry and epifluorescence approach for online monitoring of bioactive metabolites from incubated Actinobacteria in picoliter droplets

(2018) Konstantin Wink et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

High-throughput multiplexed fluorescence-activated droplet sorting

(2018) Ouriel Caen et al.   Microsystems & Nanoengineering

Differential detection photothermal spectroscopy: towards ultra-fast and sensitive label-free detection in picoliter & femtoliter droplets

(2017) Richard M. Maceiczyk et al.   LAB ON A CHIP

An Integrated Microfluidic Processor for DNA-Encoded Combinatorial Library Functional Screening

(2017) Andrew B. MacConnell et al.   ACS Combinatorial Science

An on-chip imaging droplet-sorting system: a real-time shape recognition method to screen target cells in droplets with single cell resolution

(2017) Mathias Girault et al.   Scientific Reports

Ultrahigh-throughput–directed enzyme evolution by absorbance-activated droplet sorting (AADS)

(2016) Fabrice Gielen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient laboratory evolution of computationally designed enzymes with low starting activities using fluorescence-activated droplet sorting

(2016) Richard Obexer et al.   PROTEIN ENGINEERING DESIGN & SELECTION

High-throughput screening of filamentous fungi using nanoliter-range droplet-based microfluidics

(2016) Thomas Beneyton et al.   Scientific Reports

Fluorinated Pickering Emulsions with Nonadsorbing Interfaces for Droplet-based Enzymatic Assays

(2015) Ming Pan et al.   ANALYTICAL CHEMISTRY

Droplet Barcoding for Single-Cell Transcriptomics Applied to Embryonic Stem Cells

(2015) Allon M. Klein et al.   CELL

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Rapid, targeted and culture-free viral infectivity assay in drop-based microfluidics

(2015) Ye Tao et al.   LAB ON A CHIP

Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics

(2015) Pierre-Yves Colin et al.   Nature Communications

Enhanced and homogeneous oxygen availability during incubation of microfluidic droplets

(2015) Lisa Mahler et al.   RSC Advances

Fluorinated Pickering Emulsions Impede Interfacial Transport and Form Rigid Interface for the Growth of Anchorage-Dependent Cells

(2014) Ming Pan et al.   ACS Applied Materials & Interfaces

Droplet Electrospray Ionization Mass Spectrometry for High Throughput Screening for Enzyme Inhibitors

(2014) Shuwen Sun et al.   ANALYTICAL CHEMISTRY

High-Resolution Droplet-Based Fractionation of Nano-LC Separations onto Microarrays for MALDI-MS Analysis

(2014) Simon K. Küster et al.   ANALYTICAL CHEMISTRY

Droplet-Based Microfluidics Platform for Ultra-High-Throughput Bioprospecting of Cellulolytic Microorganisms

(2014) Majdi Najah et al.   CHEMISTRY & BIOLOGY

In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire

(2014) Brandon J DeKosky et al.   NATURE MEDICINE

Analytical detection techniques for droplet microfluidics—A review

(2013) Ying Zhu et al.   ANALYTICA CHIMICA ACTA

Sensitive, High Throughput Detection of Proteins in Individual, Surfactant-Stabilized Picoliter Droplets Using Nanoelectrospray Ionization Mass Spectrometry

(2013) Clive A. Smith et al.   ANALYTICAL CHEMISTRY

Interfacing Droplet Microfluidics with Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry: Label-Free Content Analysis of Single Droplets

(2013) Simon K. Küster et al.   ANALYTICAL CHEMISTRY

From tubes to drops: droplet-based microfluidics for ultrahigh-throughput biology

(2013) T M Tran et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

Real-time image processing for label-free enrichment of Actinobacteria cultivated in picolitre droplets

(2013) Emerson Zang et al.   LAB ON A CHIP

High-throughput screening for industrial enzyme production hosts by droplet microfluidics

(2013) Staffan L. Sjostrom et al.   LAB ON A CHIP

Label Free Screening of Enzyme Inhibitors at Femtomole Scale Using Segmented Flow Electrospray Ionization Mass Spectrometry

(2012) Shuwen Sun et al.   ANALYTICAL CHEMISTRY

Picoliter Cell Lysate Assays in Microfluidic Droplet Compartments for Directed Enzyme Evolution

(2012) Balint Kintses et al.   CHEMISTRY & BIOLOGY

Quantitative screening of genes regulating tryptophan hydroxylase transcription in Caenorhabditis elegans using microfluidics and an adaptive algorithm

(2012) Hyewon Lee et al.   Integrative Biology

Characterization of sensitivity and specificity in leaky droplet-based assays

(2012) Yunhan Chen et al.   LAB ON A CHIP

A completely in vitro ultrahigh-throughput droplet-based microfluidic screening system for protein engineering and directed evolution

(2012) Ali Fallah-Araghi et al.   LAB ON A CHIP

Dynamics of molecular transport by surfactants in emulsions

(2012) Yousr Skhiri et al.   Soft Matter

Quantitative Characterization of Individual Microdroplets using Surface-Enhanced Resonance Raman Scattering Spectroscopy

(2011) Christopher D. Syme et al.   ANALYTICAL CHEMISTRY

Sampling from Nanoliter Plugs via Asymmetrical Splitting of Segmented Flow

(2010) Jing Nie et al.   ANALYTICAL CHEMISTRY

Ultrahigh-throughput screening in drop-based microfluidics for directed evolution

(2010) J. J. Agresti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

(2010) C. K. Savile et al.   SCIENCE

Analysis of Samples Stored as Individual Plugs in a Capillary by Electrospray Ionization Mass Spectrometry

(2009) Jian Pei et al.   ANALYTICAL CHEMISTRY

Controlling the Retention of Small Molecules in Emulsion Microdroplets for Use in Cell-Based Assays

(2009) Fabienne Courtois et al.   ANALYTICAL CHEMISTRY

Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity

(2009) Jean-Christophe Baret et al.   LAB ON A CHIP