Diselenide-Pemetrexed Assemblies for Combined Cancer Immuno-, Radio-, and Chemotherapies

A Cisplatin-Loaded Immunochemotherapeutic Nanohybrid Bearing Immune Checkpoint Inhibitors for Enhanced Cervical Cancer Therapy

(2018) Na Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hybrid Nanoreactors Enable an Off-the-shelf Strategy for Concurrently Enhanced Chemo-immunotherapy

(2018) Yannan Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Semiconducting Polymer Nanoenzymes with Photothermic Activity for Enhanced Cancer Therapy

(2018) Jingchao Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanoparticle-mediated Immunogenic Cell Death Enables and Potentiates Cancer Immunotherapy

(2018) Xiaopin Duan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Combinatorial library of chalcogen-containing lipidoids for intracellular delivery of genome-editing proteins

(2018) Yamin Li et al.   BIOMATERIALS

In situ formed reactive oxygen species–responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy

(2018) Chao Wang et al.   Science Translational Medicine

Low-dose X-ray radiotherapy–radiodynamic therapy via nanoscale metal–organic frameworks enhances checkpoint blockade immunotherapy

(2018) Kuangda Lu et al.   Nature Biomedical Engineering

Recent Progresses in Phototherapy-Synergized Cancer Immunotherapy

(2018) Chee Wee Ng et al.   ADVANCED FUNCTIONAL MATERIALS

Selenium-Containing Polymers: Perspectives toward Diverse Applications in Both Adaptive and Biomedical Materials

(2018) Jiahao Xia et al.   MACROMOLECULES

Wavelength-Controlled Dynamic Metathesis: A Light-Driven Exchange Reaction between Disulfide and Diselenide Bonds

(2018) Fuqiang Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Precise nanomedicine for intelligent therapy of cancer

(2018) Huabing Chen et al.   Science China-Chemistry

Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy

(2018) Quanyin Hu et al.   Nature Biomedical Engineering

Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy

(2017) Yuanzeng Min et al.   Nature Nanotechnology

Rationale and evidence to combine radiation therapy and immunotherapy for cancer treatment

(2016) Dan Ishihara et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Reprogramming the immunological microenvironment through radiation and targeting Axl

(2016) Todd A. Aguilera et al.   Nature Communications

Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy

(2016) Qian Chen et al.   Nature Communications

Immune-modulating properties of ionizing radiation: rationale for the treatment of cancer by combination radiotherapy and immune checkpoint inhibitors

(2015) Anja Derer et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Advanced therapeutic approach for the treatment of malignant pleural mesothelioma via the intrapleural administration of liposomal pemetrexed

(2015) Hidenori Ando et al.   JOURNAL OF CONTROLLED RELEASE

Selenium/tellurium containing polymer materials in nanobiotechnology

(2015) Wei Cao et al.   Nano Today

Therapeutic approaches to enhance natural killer cell cytotoxicity against cancer: the force awakens

(2015) Richard W. Childs et al.   NATURE REVIEWS DRUG DISCOVERY

Modulation of radiochemoimmunotherapy-induced B16 melanoma cell death by the pan-caspase inhibitor zVAD-fmk induces anti-tumor immunity in a HMGB1-, nucleotide- and T-cell-dependent manner

(2015) N Werthmöller et al.   Cell Death & Disease

MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer

(2014) Thomas Powles et al.   NATURE

Selenium-Containing Polymers: Promising Biomaterials for Controlled Release and Enzyme Mimics

(2013) Huaping Xu et al.   ACCOUNTS OF CHEMICAL RESEARCH

γ-Ray-Responsive Supramolecular Hydrogel Based on a Diselenide-Containing Polymer and a Peptide

(2013) Wei Cao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Low-Dose Irradiation Programs Macrophage Differentiation to an iNOS+/M1 Phenotype that Orchestrates Effective T Cell Immunotherapy

(2013) Felix Klug et al.   CANCER CELL

Effect of Pemetrexed on Innate Immune Killer Cells and Adaptive Immune T Cells in Subjects With Adenocarcinoma of the Pancreas

(2012) Marcherie Davis et al.   JOURNAL OF IMMUNOTHERAPY

Reduced Folate Carrier Independent Internalization of PEGylated Pemetrexed: A Potential Nanomedicinal Approach for Breast Cancer Therapy

(2012) Mallaredy Vandana et al.   MOLECULAR PHARMACEUTICS

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Selenite Induces Posttranscriptional Blockade of HLA-E Expression and Sensitizes Tumor Cells to CD94/NKG2A-Positive NK Cells

(2011) M. Enqvist et al.   JOURNAL OF IMMUNOLOGY

Radiation-Sensitive Diselenide Block Co-polymer Micellar Aggregates: Toward the Combination of Radiotherapy and Chemotherapy

(2011) Ning Ma et al.   LANGMUIR

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

Dual Redox Responsive Assemblies Formed from Diselenide Block Copolymers

(2009) Ning Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY